Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production L Lynch, M Nowak, B Varghese, J Clark, AE Hogan, V Toxavidis, SP Balk, ... Immunity 37 (3), 574-587, 2012 | 547 | 2012 |
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses X Michelet, L Dyck, A Hogan, RM Loftus, D Duquette, K Wei, S Beyaz, ... Nature immunology 19 (12), 1330-1340, 2018 | 491 | 2018 |
Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer D Wu, D Hu, H Chen, G Shi, IS Fetahu, F Wu, K Rabidou, R Fang, L Tan, ... Nature 559 (7715), 637-641, 2018 | 388 | 2018 |
Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue L Lynch, X Michelet, S Zhang, PJ Brennan, A Moseman, C Lester, ... Nature immunology 16 (1), 85-95, 2015 | 382 | 2015 |
Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue L Lynch, X Michelet, S Zhang, PJ Brennan, A Moseman, C Lester, ... Nature immunology 16 (1), 85, 2015 | 382 | 2015 |
Clinical anxiety, cortisol and interleukin-6: Evidence for specificity in emotion–biology relationships A O’Donovan, BM Hughes, GM Slavich, L Lynch, MT Cronin, C O’Farrelly, ... Brain, behavior, and immunity 24 (7), 1074-1077, 2010 | 337 | 2010 |
Srebp-controlled glucose metabolism is essential for NK cell functional responses N Assmann, KL O'Brien, RP Donnelly, L Dyck, V Zaiatz-Bittencourt, ... Nature immunology 18 (11), 1197-1206, 2017 | 310 | 2017 |
γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis AC Kohlgruber, ST Gal-Oz, NM LaMarche, M Shimazaki, D Duquette, ... Nature immunology 19 (5), 464-474, 2018 | 304 | 2018 |
Invariant NKT cells and CD1d+ cells amass in human omentum and are depleted in patients with cancer and obesity L Lynch, D O'Shea, DC Winter, J Geoghegan, DG Doherty, C O'Farrelly European journal of immunology 39 (7), 1893-1901, 2009 | 304 | 2009 |
Interplay between the immune system and adipose tissue in obesity MA Exley, L Hand, D O'Shea, L Lynch Journal of Endocrinology 223 (2), R41-R48, 2014 | 298 | 2014 |
Are Natural Killer Cells Protecting the Metabolically Healthy Obese Patient&quest LA Lynch, JM O'Connell, AK Kwasnik, TJ Cawood, C O'Farrelly, ... Obesity 17 (3), 601-605, 2008 | 288 | 2008 |
The relationship of omental and subcutaneous adipocyte size to metabolic disease in severe obesity J O'Connell, L Lynch, TJ Cawood, A Kwasnik, N Nolan, J Geoghegan, ... PloS one 5 (4), e9997, 2010 | 276 | 2010 |
Lactate-mediated acidification of tumor microenvironment induces apoptosis of liver-resident NK cells in colorectal liver metastasis C Harmon, MW Robinson, F Hand, D Almuaili, K Mentor, DD Houlihan, ... Cancer immunology research 7 (2), 335-346, 2019 | 233 | 2019 |
Glucagon-like peptide 1 analogue therapy directly modulates innate immune-mediated inflammation in individuals with type 2 diabetes mellitus AE Hogan, G Gaoatswe, L Lynch, MA Corrigan, C Woods, J O’Connell, ... Diabetologia 57 (4), 781-784, 2014 | 204 | 2014 |
Adipose Type One Innate Lymphoid Cells Regulate Macrophage Homeostasis through Targeted Cytotoxicity S Boulenouar, X Michelet, D Duquette, D Alvarez, AE Hogan, C Dold, ... Immunity 46 (2), 273-286, 2017 | 195 | 2017 |
Natural killer cells in obesity: impaired function and increased susceptibility to the effects of cigarette smoke D O'Shea, TJ Cawood, C O'Farrelly, L Lynch PloS one 5 (1), e8660, 2010 | 186 | 2010 |
Adipose tissue inflammation in the pathogenesis of type 2 diabetes A Kohlgruber, L Lynch Current diabetes reports 15 (11), 92, 2015 | 181 | 2015 |
iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy L Lynch, AE Hogan, D Duquette, C Lester, A Banks, K LeClair, DE Cohen, ... Cell Metabolism 24 (3), 510-519, 2016 | 179 | 2016 |
Altered distribution and increased IL-17 production by mucosal-associated invariant T cells in adult and childhood obesity E Carolan, LM Tobin, BA Mangan, M Corrigan, G Gaoatswe, G Byrne, ... The Journal of Immunology, 1402945, 2015 | 179 | 2015 |
Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis AE Hogan, AM Tobin, T Ahern, MA Corrigan, G Gaoatswe, R Jackson, ... Diabetologia 54 (11), 2745-2754, 2011 | 179 | 2011 |