Trends in GPCR drug discovery: new agents, targets and indications AS Hauser, MM Attwood, M Rask-Andersen, HB Schiöth, DE Gloriam Nature reviews Drug discovery 16 (12), 829-842, 2017 | 2387 | 2017 |
Trends in the exploitation of novel drug targets M Rask-Andersen, MS Almén, HB Schiöth Nature reviews Drug discovery 10 (8), 579-590, 2011 | 1040 | 2011 |
The druggable genome: evaluation of drug targets in clinical trials suggests major shifts in molecular class and indication M Rask-Andersen, S Masuram, HB Schiöth Annual review of pharmacology and toxicology 54 (1), 9-26, 2014 | 353 | 2014 |
Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease T Karlsson, M Rask-Andersen, G Pan, J Höglund, C Wadelius, WE Ek, ... Nature medicine 25 (9), 1390-1395, 2019 | 229 | 2019 |
Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects M Rask-Andersen, T Karlsson, WE Ek, Å Johansson Nature communications 10 (1), 339, 2019 | 210 | 2019 |
Advances in kinase targeting: current clinical use and clinical trials M Rask-Andersen, J Zhang, D Fabbro, HB Schiöth Trends in pharmacological sciences 35 (11), 604-620, 2014 | 209 | 2014 |
Gene-environment interaction study for BMI reveals interactions between genetic factors and physical activity, alcohol consumption and socioeconomic status M Rask-Andersen, T Karlsson, WE Ek, Å Johansson PLoS genetics 13 (9), e1006977, 2017 | 157 | 2017 |
Molecular mechanisms underlying anorexia nervosa: focus on human gene association studies and systems controlling food intake M Rask-Andersen, PK Olszewski, AS Levine, HB Schiöth Brain research reviews 62 (2), 147-164, 2010 | 150 | 2010 |
Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers S Voisin, MS Almén, GY Zheleznyakova, L Lundberg, S Zarei, S Castillo, ... Genome medicine 7, 1-16, 2015 | 147 | 2015 |
A debate on current eating disorder diagnoses in light of neurobiological findings: is it time for a spectrum model? SJ Brooks, M Rask-Andersen, C Benedict, HB Schiöth BMC psychiatry 12, 1-11, 2012 | 139 | 2012 |
Solute carriers as drug targets: current use, clinical trials and prospective M Rask-Andersen, S Masuram, R Fredriksson, HB Schiöth Molecular aspects of medicine 34 (2-3), 702-710, 2013 | 114 | 2013 |
Epigenome-wide association study reveals differential DNA methylation in individuals with a history of myocardial infarction M Rask-Andersen, D Martinsson, M Ahsan, S Enroth, WE Ek, ... Human molecular genetics 25 (21), 4739-4748, 2016 | 91 | 2016 |
Soluble ligands as drug targets MM Attwood, J Jonsson, M Rask-Andersen, HB Schiöth Nature Reviews Drug Discovery 19 (10), 695-710, 2020 | 80 | 2020 |
The relative contribution of DNA methylation and genetic variants on protein biomarkers for human diseases M Ahsan, WE Ek, M Rask-Andersen, T Karlsson, A Lind-Thomsen, ... PLoS genetics 13 (9), e1007005, 2017 | 77 | 2017 |
Improved power and precision with whole genome sequencing data in genome-wide association studies of inflammatory biomarkers J Höglund, N Rafati, M Rask-Andersen, S Enroth, T Karlsson, WE Ek, ... Scientific reports 9 (1), 16844, 2019 | 66 | 2019 |
Orphan drugs and their impact on pharmaceutical development MM Attwood, M Rask-Andersen, HB Schiöth Trends in pharmacological sciences 39 (6), 525-535, 2018 | 62 | 2018 |
Genetic and expression studies of SMN2 gene in Russian patients with spinal muscular atrophy type II and III GY Zheleznyakova, AV Kiselev, VG Vakharlovsky, M Rask-Andersen, ... BMC medical genetics 12, 1-9, 2011 | 56 | 2011 |
Determination of the obesity-associated gene variants within the entire FTO gene by ultra-deep targeted sequencing in obese and lean children M Sällman Almén, M Rask-Andersen, JA Jacobsson, A Ameur, I Kalnina, ... International journal of obesity 37 (3), 424-431, 2013 | 49 | 2013 |
Tea and coffee consumption in relation to DNA methylation in four European cohorts WE Ek, EW Tobi, M Ahsan, E Lampa, E Ponzi, SA Kyrtopoulos, ... Human molecular genetics 26 (16), 3221-3231, 2017 | 48 | 2017 |
Personality, lifestyle and job satisfaction: causal association between neuroticism and job satisfaction using Mendelian randomisation in the UK biobank cohort G Rukh, J Dang, G Olivo, DM Ciuculete, M Rask-Andersen, HB Schiöth Translational Psychiatry 10 (1), 11, 2020 | 40 | 2020 |