| Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1α inhibition FA Siddiqui, G Prakasam, S Chattopadhyay, AU Rehman, RA Padder, ... Scientific reports 8 (1), 8323, 2018 | 135 | 2018 |
| Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2 MA Iqbal, FA Siddiqui, V Gupta, S Chattopadhyay, P Gopinath, B Kumar, ... Molecular cancer 12, 1-12, 2013 | 106 | 2013 |
| Silibinin induces metabolic crisis in triple‐negative breast cancer cells by modulating EGFR‐MYC‐TXNIP axis: potential therapeutic implications MA Iqbal, S Chattopadhyay, FA Siddiqui, A Ur Rehman, S Siddiqui, ... The FEBS journal 288 (2), 471-485, 2021 | 42 | 2021 |
| PDE6D inhibitors with a new design principle selectively block K-Ras activity FA Siddiqui, C Alam, P Rosenqvist, M Ora, A Sabt, GB Manoharan, ... ACS omega 5 (1), 832-842, 2019 | 30 | 2019 |
| Missense mutations in pyruvate kinase M2 promote cancer metabolism, oxidative endurance, anchorage independence, and tumor growth in a dominant negative manner MA Iqbal, FA Siddiqui, N Chaman, V Gupta, B Kumar, P Gopinath, ... Journal of Biological Chemistry 289 (12), 8098-8105, 2014 | 28 | 2014 |
| Multiomics integrative analysis reveals antagonistic roles of CBX2 and CBX7 in metabolic reprogramming of breast cancer MA Iqbal, S Siddiqui, A Ur Rehman, FA Siddiqui, P Singh, B Kumar, ... Molecular oncology 15 (5), 1450-1465, 2021 | 26 | 2021 |
| ERK2-pyruvate kinase axis permits phorbol 12-myristate 13-acetate-induced megakaryocyte differentiation in K562 cells N Chaman, MA Iqbal, FA Siddiqui, P Gopinath, RNK Bamezai Journal of Biological Chemistry 290 (39), 23803-23815, 2015 | 17 | 2015 |
| A subset of flavaglines inhibits KRAS nanoclustering and activation H Yurugi, Y Zhuang, FA Siddiqui, H Liang, S Rosigkeit, Y Zeng, ... Journal of cell science 133 (12), jcs244111, 2020 | 15 | 2020 |
| Novel small molecule Hsp90/Cdc37 interface inhibitors indirectly target K-Ras-signaling FA Siddiqui, H Parkkola, V Vukic, C Oetken-Lindholm, A Jaiswal, ... Cancers 13 (4), 927, 2021 | 14 | 2021 |
| Medium-Throughput Detection of Hsp90/Cdc37 Protein–Protein Interaction Inhibitors Using a Split Renilla Luciferase-Based Assay FA Siddiqui, H Parkkola, GB Manoharan, D Abankwa SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (2), 195-206, 2020 | 13 | 2020 |
| Opposite feedback from mTORC1 to H-ras and K-ras4B downstream of SREBP1 IMD Posada, B Lectez, FA Siddiqui, C Oetken-Lindholm, M Sharma, ... Scientific Reports 7 (1), 8944, 2017 | 13 | 2017 |
| NRAS is unique among RAS proteins in requiring ICMT for trafficking to the plasma membrane IM Ahearn, F Siddiqui, D Abankwa, MR Philips Life Science Alliance 4 (5), 2021 | 11 | 2021 |
| Elaiophylin is a potent hsp90/cdc37 protein interface inhibitor with k-ras nanocluster selectivity FA Siddiqui, V Vukic, TA Salminen, D Abankwa Biomolecules 11 (6), 836, 2021 | 7 | 2021 |
| FLIM-FRET analysis of Ras nanoclustering and membrane-anchorage H Parkkola, FA Siddiqui, C Oetken-Lindholm, D Abankwa Ras Activity and Signaling: Methods and Protocols, 233-250, 2021 | 7 | 2021 |
| Development of Novel Drugs Targeting Chaperones of Oncogenic K-Ras FA Siddiqui Åbo Akademi-Åbo Akademi University, 2021 | | 2021 |
| ERK2-PYRUVATE KINASE AXIS PERMITS PMA-INDUCED MEGAKARYOCYTE DIFFERENTIATION IN K562 CELLS N Chaman, MA Iqbal, FA Siddiqui, P Gopinath, RNK Bamezai | | 2015 |
Gopinath PrakasamUT Southwestern Medical Center在 utsouthwestern.edu 的电子邮件经过验证
