| Writing of H3K4Me3 overcomes epigenetic silencing in a sustained but context-dependent manner D Cano-Rodriguez, RAF Gjaltema, LJ Jilderda, P Jellema, ... Nature communications 7 (1), 12284, 2016 | 275 | 2016 |
| Molecular insights into prolyl and lysyl hydroxylation of fibrillar collagens in health and disease RAF Gjaltema, RA Bank Critical reviews in biochemistry and molecular biology 52 (1), 74-95, 2017 | 160 | 2017 |
| Disentangling mechanisms involved in collagen pyridinoline cross-linking: The immunophilin FKBP65 is critical for dimerization of lysyl hydroxylase 2 RAF Gjaltema, MM van der Stoel, M Boersema, RA Bank Proceedings of the National Academy of Sciences 113 (26), 7142-7147, 2016 | 75 | 2016 |
| Procollagen lysyl hydroxylase 2 expression is regulated by an alternative downstream transforming growth factor β-1 activation mechanism RAF Gjaltema, S de Rond, MG Rots, RA Bank Journal of Biological Chemistry 290 (47), 28465-28476, 2015 | 73 | 2015 |
| HDAC1-3 inhibitor MS-275 enhances IL10 expression in RAW264.7 macrophages and reduces cigarette smoke-induced airway inflammation in mice NGJ Leus, T van den Bosch, PE van der Wouden, K Krist, ME Ourailidou, ... Scientific reports 7 (1), 45047, 2017 | 72 | 2017 |
| Enhancer of zeste homolog-2 (EZH2) methyltransferase regulates transgelin/smooth muscle-22α expression in endothelial cells in response to interleukin-1β and transforming … M Maleszewska, RAF Gjaltema, G Krenning, MC Harmsen Cellular signalling 27 (8), 1589-1596, 2015 | 68 | 2015 |
| Advances of epigenetic editing RAF Gjaltema, MG Rots Current opinion in chemical biology 57, 75-81, 2020 | 64 | 2020 |
| Targeted epigenetic editing of SPDEF reduces mucus production in lung epithelial cells J Song, D Cano-Rodriquez, M Winkle, RAF Gjaltema, D Goubert, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (3 …, 2017 | 55 | 2017 |
| Distal and proximal cis-regulatory elements sense X chromosome dosage and developmental state at the Xist locus RAF Gjaltema, T Schwämmle, P Kautz, M Robson, R Schöpflin, LR Lustig, ... Molecular Cell 82 (1), 190-208. e17, 2022 | 36 | 2022 |
| Ascorbic acid promotes a TGFβ1‐induced myofibroblast phenotype switch B Piersma, OY Wouters, S de Rond, M Boersema, RAF Gjaltema, ... Physiological reports 5 (17), e13324, 2017 | 36 | 2017 |
| CRISPR/dCas9 switch systems for temporal transcriptional control RAF Gjaltema, EG Schulz Epigenome Editing: Methods and Protocols, 167-185, 2018 | 25 | 2018 |
| Reciprocal regulation of endothelial–mesenchymal transition by MAPK7 and EZH2 in intimal hyperplasia and coronary artery disease B Vanchin, M Sol, RAF Gjaltema, M Brinker, B Kiers, AC Pereira, ... Scientific Reports 11 (1), 17764, 2021 | 11 | 2021 |
| CasTuner is a degron and CRISPR/Cas-based toolkit for analog tuning of endogenous gene expression G Noviello, RAF Gjaltema, EG Schulz Nature Communications 14 (1), 3225, 2023 | 10 | 2023 |
| KRAB-Induced Heterochromatin Effectively Silences PLOD2 Gene Expression in Somatic Cells and Is Resilient to TGFβ1 Activation RAF Gjaltema, D Goubert, C Huisman, C Pilar García Tobilla, M Koncz, ... International Journal of Molecular Sciences 21 (10), 3634, 2020 | 7 | 2020 |
| Reducing lysyl hydroxylase 2 expression in a fibrotic environment by introducing repressive epigenetic marks in the PLOD2 promoter RAF Gjaltema, C Huisman, MG Rots, RA Bank JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE 6, 98-98, 2012 | 3 | 2012 |
| Antisense transcription can induce expression memory via stable promoter repression V Mutzel, T Schwämmle, S Oeverdieck, L Librenjak, B Boesen, M Bothe, ... bioRxiv, 2024.03. 06.583761, 2024 | | 2024 |
| Modifications of collagen and chromatin in ECM-related disease: Uncovering therapeutic targets for fibrosis and cancer RAF Gjaltema | | 2016 |
| THE HISTONE DEACETYLASE INHIBITOR TRICHOSTATIN A MODULATES CYTOKINE PRODUCTION IN HUMAN B CELLS N Lepse, T Bijma, RAF Gjaltema, WH Abdulahad, P Heeringa THE REGULATORY AND EFFECTOR FUNCTIONS OF B CELLS IN ANCA-ASSOCIATED …, 2014 | | 2014 |
| GENE EXPRESSION REGULATION OF COLLAGEN LYSYL HYDROXYLASE 2: 030 R Gjaltema, M Rots, R Bank Wound Repair and Regeneration 19 (5), 2011 | | 2011 |
| YAP SYNERGIZES WITH THE TGFΒ/SMAD AXIS TO REGULATE PRO-FIBROTIC SIGNALING B Piersma, RAF Gjaltema, S de Rond, T Borghuis, NP Cavanzo, ... | | |
