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Michael Groll
Michael Groll
Professor of Biochemistry, TU Munich
在 tum.de 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
Structure of 20S proteasome from yeast at 2.4 Å resolution
M Groll, L Ditzel, J Löwe, D Stock, M Bochtler, HD Bartunik, R Huber
Nature 386 (6624), 463-471, 1997
29821997
A gated channel into the proteasome core particle
M Groll, M Bajorek, A Köhler, L Moroder, DM Rubin, R Huber, ...
Nature structural biology 7 (11), 1062-1067, 2000
10932000
The proteasome
M Bochtler, L Ditzel, M Groll, C Hartmann, R Huber
Annual review of biophysics and biomolecular structure 28 (1), 295-317, 1999
6741999
Crystal structure of the boronic acid-based proteasome inhibitor bortezomib in complex with the yeast 20S proteasome
M Groll, CR Berkers, HL Ploegh, H Ovaa
Structure 14 (3), 451-456, 2006
5892006
Immuno-and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity
EM Huber, M Basler, R Schwab, W Heinemeyer, CJ Kirk, M Groettrup, ...
Cell 148 (4), 727-738, 2012
5482012
20S proteasome and its inhibitors: crystallographic knowledge for drug development
L Borissenko, M Groll
Chemical reviews 107 (3), 687-717, 2007
5142007
Cleavage motifs of the yeast 20S proteasome β subunits deduced from digests of enolase 1
AK Nussbaum, TP Dick, W Keilholz, M Schirle, S Stevanović, K Dietz, ...
Proceedings of the National Academy of Sciences 95 (21), 12504-12509, 1998
4671998
Crystal structure of epoxomicin: 20S proteasome reveals a molecular basis for selectivity of α ‘, β ‘-epoxyketone proteasome inhibitors
M Groll, KB Kim, N Kairies, R Huber, CM Crews
Journal of the American Chemical Society 122 (6), 1237-1238, 2000
4042000
Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction
P Schreiner, X Chen, K Husnjak, L Randles, N Zhang, S Elsasser, ...
Nature 453 (7194), 548-552, 2008
4012008
The catalytic sites of 20S proteasomes and their role in subunit maturation: a mutational and crystallographic study
M Groll, W Heinemeyer, S Jäger, T Ullrich, M Bochtler, DH Wolf, R Huber
Proceedings of the National Academy of Sciences 96 (20), 10976-10983, 1999
3911999
Contribution of proteasomal β-subunits to the cleavage of peptide substrates analyzed with yeast mutants
TP Dick, AK Nussbaum, M Deeg, W Heinemeyer, M Groll, M Schirle, ...
Journal of Biological Chemistry 273 (40), 25637-25646, 1998
3801998
A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism
M Groll, B Schellenberg, AS Bachmann, CR Archer, R Huber, TK Powell, ...
Nature 452 (7188), 755-758, 2008
3722008
Crystal structures of salinosporamide A (NPI-0052) and B (NPI-0047) in complex with the 20S proteasome reveal important consequences of β-lactone ring opening and a mechanism …
M Groll, R Huber, BCM Potts
Journal of the American Chemical Society 128 (15), 5136-5141, 2006
3642006
Molecular machines for protein degradation
M Groll, M Bochtler, H Brandstetter, T Clausen, R Huber
Chembiochem 6 (2), 222-256, 2005
2892005
The 26S proteasome: assembly and function of a destructive machine
N Gallastegui, M Groll
Trends in biochemical sciences 35 (11), 634-642, 2010
2642010
Substrate access and processing by the 20S proteasome core particle
M Groll, R Huber
The international journal of biochemistry & cell biology 35 (5), 606-616, 2003
2632003
Marizomib, a proteasome inhibitor for all seasons: preclinical profile and a framework for clinical trials
B C Potts, M X Albitar, K C Anderson, S Baritaki, C Berkers, B Bonavida, ...
Current cancer drug targets 11 (3), 254-284, 2011
2602011
The architecture of functional modules in the Hsp90 co‐chaperone Sti1/Hop
AB Schmid, S Lagleder, MA Gräwert, A Röhl, F Hagn, SK Wandinger, ...
The EMBO journal 31 (6), 1506-1517, 2012
2572012
Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach
M Groll, R Huber
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1695 (1-3), 33-44, 2004
2552004
Mechanism and regulation of DNA-protein crosslink repair by the DNA-dependent metalloprotease SPRTN
J Stingele, R Bellelli, F Alte, G Hewitt, G Sarek, SL Maslen, SE Tsutakawa, ...
Molecular cell 64 (4), 688-703, 2016
2492016
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