| Structure of 20S proteasome from yeast at 2.4 Å resolution M Groll, L Ditzel, J Löwe, D Stock, M Bochtler, HD Bartunik, R Huber Nature 386 (6624), 463-471, 1997 | 2982 | 1997 |
| A gated channel into the proteasome core particle M Groll, M Bajorek, A Köhler, L Moroder, DM Rubin, R Huber, ... Nature structural biology 7 (11), 1062-1067, 2000 | 1093 | 2000 |
| The proteasome M Bochtler, L Ditzel, M Groll, C Hartmann, R Huber Annual review of biophysics and biomolecular structure 28 (1), 295-317, 1999 | 674 | 1999 |
| Crystal structure of the boronic acid-based proteasome inhibitor bortezomib in complex with the yeast 20S proteasome M Groll, CR Berkers, HL Ploegh, H Ovaa Structure 14 (3), 451-456, 2006 | 589 | 2006 |
| Immuno-and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity EM Huber, M Basler, R Schwab, W Heinemeyer, CJ Kirk, M Groettrup, ... Cell 148 (4), 727-738, 2012 | 548 | 2012 |
| 20S proteasome and its inhibitors: crystallographic knowledge for drug development L Borissenko, M Groll Chemical reviews 107 (3), 687-717, 2007 | 514 | 2007 |
| Cleavage motifs of the yeast 20S proteasome β subunits deduced from digests of enolase 1 AK Nussbaum, TP Dick, W Keilholz, M Schirle, S Stevanović, K Dietz, ... Proceedings of the National Academy of Sciences 95 (21), 12504-12509, 1998 | 467 | 1998 |
| Crystal structure of epoxomicin: 20S proteasome reveals a molecular basis for selectivity of α ‘, β ‘-epoxyketone proteasome inhibitors M Groll, KB Kim, N Kairies, R Huber, CM Crews Journal of the American Chemical Society 122 (6), 1237-1238, 2000 | 404 | 2000 |
| Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction P Schreiner, X Chen, K Husnjak, L Randles, N Zhang, S Elsasser, ... Nature 453 (7194), 548-552, 2008 | 401 | 2008 |
| The catalytic sites of 20S proteasomes and their role in subunit maturation: a mutational and crystallographic study M Groll, W Heinemeyer, S Jäger, T Ullrich, M Bochtler, DH Wolf, R Huber Proceedings of the National Academy of Sciences 96 (20), 10976-10983, 1999 | 391 | 1999 |
| Contribution of proteasomal β-subunits to the cleavage of peptide substrates analyzed with yeast mutants TP Dick, AK Nussbaum, M Deeg, W Heinemeyer, M Groll, M Schirle, ... Journal of Biological Chemistry 273 (40), 25637-25646, 1998 | 380 | 1998 |
| A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism M Groll, B Schellenberg, AS Bachmann, CR Archer, R Huber, TK Powell, ... Nature 452 (7188), 755-758, 2008 | 372 | 2008 |
| Crystal structures of salinosporamide A (NPI-0052) and B (NPI-0047) in complex with the 20S proteasome reveal important consequences of β-lactone ring opening and a mechanism … M Groll, R Huber, BCM Potts Journal of the American Chemical Society 128 (15), 5136-5141, 2006 | 364 | 2006 |
| Molecular machines for protein degradation M Groll, M Bochtler, H Brandstetter, T Clausen, R Huber Chembiochem 6 (2), 222-256, 2005 | 289 | 2005 |
| The 26S proteasome: assembly and function of a destructive machine N Gallastegui, M Groll Trends in biochemical sciences 35 (11), 634-642, 2010 | 264 | 2010 |
| Substrate access and processing by the 20S proteasome core particle M Groll, R Huber The international journal of biochemistry & cell biology 35 (5), 606-616, 2003 | 263 | 2003 |
| Marizomib, a proteasome inhibitor for all seasons: preclinical profile and a framework for clinical trials B C Potts, M X Albitar, K C Anderson, S Baritaki, C Berkers, B Bonavida, ... Current cancer drug targets 11 (3), 254-284, 2011 | 260 | 2011 |
| The architecture of functional modules in the Hsp90 co‐chaperone Sti1/Hop AB Schmid, S Lagleder, MA Gräwert, A Röhl, F Hagn, SK Wandinger, ... The EMBO journal 31 (6), 1506-1517, 2012 | 257 | 2012 |
| Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach M Groll, R Huber Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1695 (1-3), 33-44, 2004 | 255 | 2004 |
| Mechanism and regulation of DNA-protein crosslink repair by the DNA-dependent metalloprotease SPRTN J Stingele, R Bellelli, F Alte, G Hewitt, G Sarek, SL Maslen, SE Tsutakawa, ... Molecular cell 64 (4), 688-703, 2016 | 249 | 2016 |
