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Thomas Wieland
Thomas Wieland
Professor für Pharmakologie, Universität Heidelberg
在 uni-heidelberg.de 的电子邮件经过验证 - 首页
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Transcriptome and genome sequencing uncovers functional variation in humans
T Lappalainen, M Sammeth, MR Friedländer, PAC ‘t Hoen, J Monlong, ...
Nature 501 (7468), 506-511, 2013
20552013
The genetic architecture of type 2 diabetes
C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, ...
Nature 536 (7614), 41-47, 2016
12472016
Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study
A Rauch, D Wieczorek, E Graf, T Wieland, S Endele, T Schwarzmayr, ...
The Lancet 380 (9854), 1674-1682, 2012
12252012
Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia
A Freischmidt, T Wieland, B Richter, W Ruf, V Schaeffer, K Müller, ...
Nature neuroscience 18 (5), 631-636, 2015
8322015
Enhanced Sarcoplasmic Reticulum Ca2+ Leak and Increased Na+-Ca2+ Exchanger Function Underlie Delayed Afterdepolarizations in Patients With Chronic …
N Voigt, N Li, Q Wang, W Wang, AW Trafford, I Abu-Taha, Q Sun, ...
Circulation 125 (17), 2059-2070, 2012
6702012
A deep proteome and transcriptome abundance atlas of 29 healthy human tissues
D Wang, B Eraslan, T Wieland, B Hallström, T Hopf, DP Zolg, J Zecha, ...
Molecular systems biology 15 (2), e8503, 2019
6102019
ADP receptors of platelets and their inhibition
C Gachet
Thrombosis and haemostasis 86 (07), 222-232, 2001
5752001
Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension
F Beuschlein, S Boulkroun, A Osswald, T Wieland, HN Nielsen, ...
Nature genetics 45 (4), 440-444, 2013
5632013
Mutations in the deubiquitinase gene USP8 cause Cushing's disease
M Reincke, S Sbiera, A Hayakawa, M Theodoropoulou, A Osswald, ...
Nature genetics 47 (1), 31-38, 2015
5492015
Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling
M Felcht, R Luck, A Schering, P Seidel, K Srivastava, J Hu, A Bartol, ...
The Journal of clinical investigation 122 (6), 1991-2005, 2012
5052012
Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome
F Beuschlein, M Fassnacht, G Assié, D Calebiro, CA Stratakis, A Osswald, ...
New England Journal of Medicine 370 (11), 1019-1028, 2014
4102014
Calmodulin mutations associated with recurrent cardiac arrest in infants
L Crotti, CN Johnson, E Graf, GM De Ferrari, BF Cuneo, M Ovadia, ...
Circulation 127 (9), 1009-1017, 2013
4092013
How reliable are G-protein-coupled receptor antibodies?
MC Michel, T Wieland, G Tsujimoto
Naunyn-Schmiedeberg's archives of pharmacology 379, 385-388, 2009
3702009
Exome sequencing reveals de novo WDR45 mutations causing a phenotypically distinct, X-linked dominant form of NBIA
TB Haack, P Hogarth, MC Kruer, A Gregory, T Wieland, T Schwarzmayr, ...
The American journal of human genetics 91 (6), 1144-1149, 2012
3522012
Effect of predicted protein-truncating genetic variants on the human transcriptome
MA Rivas, M Pirinen, DF Conrad, M Lek, EK Tsang, KJ Karczewski, ...
Science 348 (6235), 666-669, 2015
3412015
Structure of Gαq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs
S Lutz, A Shankaranarayanan, C Coco, M Ridilla, MR Nance, C Vettel, ...
Science 318 (5858), 1923-1927, 2007
2712007
Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories
PAC 't Hoen, MR Friedländer, J Almlöf, M Sammeth, I Pulyakhina, ...
Nature biotechnology 31 (11), 1015-1022, 2013
2702013
Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy
J Winkelmann, L Lin, B Schormair, BR Kornum, J Faraco, G Plazzi, ...
Human molecular genetics 21 (10), 2205-2210, 2012
2642012
The guanine nucleotide exchange factor p63RhoGEF, a specific link between Gq/11-coupled receptor signaling and RhoA
S Lutz, A Freichel-Blomquist, Y Yang, U Rumenapp, KH Jakobs, ...
Journal of Biological Chemistry 280 (12), 11134-11139, 2005
2632005
Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease
C Kornblum, TJ Nicholls, TB Haack, S Schöler, V Peeva, K Danhauser, ...
Nature genetics 45 (2), 214-219, 2013
2582013
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