Gut microbiota functions: metabolism of nutrients and other food components I Rowland, G Gibson, A Heinken, K Scott, J Swann, I Thiele, K Tuohy European journal of nutrition 57, 1-24, 2018 | 2371 | 2018 |
Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v. 3.0 L Heirendt, S Arreckx, T Pfau, SN Mendoza, A Richelle, A Heinken, ... Nature protocols 14 (3), 639-702, 2019 | 1035 | 2019 |
Generation of genome-scale metabolic reconstructions for 773 members of the human gut microbiota S Magnúsdóttir, A Heinken, L Kutt, DA Ravcheev, E Bauer, A Noronha, ... Nature biotechnology 35 (1), 81-89, 2017 | 724 | 2017 |
Recon3D enables a three-dimensional view of gene variation in human metabolism E Brunk, S Sahoo, DC Zielinski, A Altunkaya, A Dräger, N Mih, F Gatto, ... Nature biotechnology 36 (3), 272-281, 2018 | 636 | 2018 |
The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease A Noronha, J Modamio, Y Jarosz, E Guerard, N Sompairac, G Preciat, ... Nucleic acids research 47 (D1), D614-D624, 2019 | 322 | 2019 |
Systematic assessment of secondary bile acid metabolism in gut microbes reveals distinct metabolic capabilities in inflammatory bowel disease A Heinken, DA Ravcheev, F Baldini, L Heirendt, RMT Fleming, I Thiele Microbiome 7, 1-18, 2019 | 249 | 2019 |
Systems-level characterization of a host-microbe metabolic symbiosis in the mammalian gut A Heinken, S Sahoo, RMT Fleming, I Thiele Gut microbes 4 (1), 28-40, 2013 | 249 | 2013 |
Functional metabolic map of Faecalibacterium prausnitzii, a beneficial human gut microbe A Heinken, MT Khan, G Paglia, DA Rodionov, HJM Harmsen, I Thiele Journal of bacteriology 196 (18), 3289-3302, 2014 | 225 | 2014 |
Personalized whole‐body models integrate metabolism, physiology, and the gut microbiome I Thiele, S Sahoo, A Heinken, J Hertel, L Heirendt, MK Aurich, ... Molecular systems biology 16 (5), e8982, 2020 | 159 | 2020 |
The gut microbial metabolite formate exacerbates colorectal cancer progression D Ternes, M Tsenkova, VI Pozdeev, M Meyers, E Koncina, S Atatri, ... Nature metabolism 4 (4), 458-475, 2022 | 134 | 2022 |
Metabolic network analysis reveals altered bile acid synthesis and metabolism in Alzheimer’s disease P Baloni, CC Funk, J Yan, JT Yurkovich, A Kueider-Paisley, K Nho, ... Cell Reports Medicine 1 (8), 2020 | 132 | 2020 |
The contribution of gut bacterial metabolites in the human immune signaling pathway of non-communicable diseases F Hosseinkhani, A Heinken, I Thiele, PW Lindenburg, AC Harms, ... Gut microbes 13 (1), 1882927, 2021 | 130 | 2021 |
Integrated analyses of microbiome and longitudinal metabolome data reveal microbial-host interactions on sulfur metabolism in Parkinson’s disease J Hertel, AC Harms, A Heinken, F Baldini, CC Thinnes, E Glaab, ... Cell reports 29 (7), 1767-1777. e8, 2019 | 130 | 2019 |
The Microbiome Modeling Toolbox: from microbial interactions to personalized microbial communities F Baldini, A Heinken, L Heirendt, S Magnusdottir, RMT Fleming, I Thiele Bioinformatics 35 (13), 2332-2334, 2019 | 130 | 2019 |
A systems biology approach to studying the role of microbes in human health I Thiele, A Heinken, RMT Fleming Current opinion in biotechnology 24 (1), 4-12, 2013 | 120 | 2013 |
Anoxic Conditions Promote Species-Specific Mutualism between Gut Microbes In Silico A Heinken, I Thiele Applied and environmental microbiology 81 (12), 4049-4061, 2015 | 116 | 2015 |
Systematic prediction of health-relevant human-microbial co-metabolism through a computational framework A Heinken, I Thiele Gut microbes 6 (2), 120-130, 2015 | 105 | 2015 |
Systems biology of host–microbe metabolomics A Heinken, I Thiele Wiley Interdisciplinary Reviews: Systems Biology and Medicine 7 (4), 195-219, 2015 | 94 | 2015 |
Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine A Heinken, J Hertel, G Acharya, DA Ravcheev, M Nyga, OE Okpala, ... Nature Biotechnology 41 (9), 1320-1331, 2023 | 92 | 2023 |
Integrated in vitro and in silico modeling delineates the molecular effects of a synbiotic regimen on colorectal-cancer-derived cells K Greenhalgh, J Ramiro-Garcia, A Heinken, P Ullmann, T Bintener, ... Cell reports 27 (5), 1621-1632. e9, 2019 | 70 | 2019 |