Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound VJN Bykov, N Issaeva, A Shilov, M Hultcrantz, E Pugacheva, P Chumakov, ... Nature medicine 8 (3), 282-288, 2002 | 1303 | 2002 |
HEF1-dependent Aurora A activation induces disassembly of the primary cilium EN Pugacheva, SA Jablonski, TR Hartman, EP Henske, EA Golemis Cell 129 (7), 1351-1363, 2007 | 972 | 2007 |
Primary cilia and the cell cycle OV Plotnikova, EN Pugacheva, EA Golemis Methods in cell biology 94, 137-160, 2009 | 275 | 2009 |
The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome EN Pugacheva, EA Golemis Nature cell biology 7 (10), 937-946, 2005 | 273 | 2005 |
HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells M Natarajan, JE Stewart, EA Golemis, EN Pugacheva, K Alexandropoulos, ... Oncogene 25 (12), 1721-1732, 2006 | 236 | 2006 |
Cell cycle–dependent ciliogenesis and cancer OV Plotnikova, EA Golemis, EN Pugacheva Cancer research 68 (7), 2058-2061, 2008 | 198 | 2008 |
Calmodulin activation of Aurora-A kinase (AURKA) is required during ciliary disassembly and in mitosis OV Plotnikova, AS Nikonova, YV Loskutov, PY Kozyulina, EN Pugacheva, ... Molecular biology of the cell 23 (14), 2658-2670, 2012 | 183 | 2012 |
NEDD9 promotes oncogenic signaling in mammary tumor development E Izumchenko, MK Singh, OV Plotnikova, N Tikhmyanova, JL Little, ... Cancer research 69 (18), 7198-7206, 2009 | 151 | 2009 |
Novel gain of function activity of p53 mutants: activation of the dUTPase gene expression leading to resistance to 5-fluorouracil EN Pugacheva, AV Ivanov, JE Kravchenko, BP Kopnin, AJ Levine, ... Oncogene 21 (30), 4595-4600, 2002 | 125 | 2002 |
KAP1 promotes proliferation and metastatic progression of breast cancer cells JB Addison, C Koontz, JH Fugett, CJ Creighton, D Chen, MK Farrugia, ... Cancer research 75 (2), 344-355, 2015 | 124 | 2015 |
Rapid calcium-dependent activation of Aurora-A kinase OV Plotnikova, EN Pugacheva, RL Dunbrack, EA Golemis Nature communications 1 (1), 64, 2010 | 97 | 2010 |
HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks EN Pugacheva, EA Golemis Cell Cycle 5 (4), 384-391, 2006 | 88 | 2006 |
Aurora A kinase activity influences calcium signaling in kidney cells OV Plotnikova, EA Golemis The Journal of cell biology 193 (6), 1021, 2011 | 82 | 2011 |
Interdependence of cell attachment and cell cycle signaling EN Pugacheva, F Roegiers, EA Golemis Current opinion in cell biology 18 (5), 507-515, 2006 | 79 | 2006 |
Deregulation of HEF1 impairs M-phase progression by disrupting the RhoA activation cycle D Dadke, M Jarnik, EN Pugacheva, MK Singh, EA Golemis Molecular biology of the cell 17 (3), 1204-1217, 2006 | 68 | 2006 |
Role for chondroitin sulfate glycosaminoglycan in NEDD9-mediated breast cancer cell growth J Iida, J Dorchak, R Clancy, J Slavik, R Ellsworth, Y Katagiri, ... Experimental cell research 330 (2), 358-370, 2015 | 61 | 2015 |
LPA signaling is regulated through the primary cilium: a novel target in glioblastoma YV Loskutov, CL Griffin, KM Marinak, A Bobko, NV Margaryan, ... Oncogene 37 (11), 1457-1471, 2018 | 54 | 2018 |
NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration J Zhong, JB Baquiran, N Bonakdar, J Lees, YW Ching, E Pugacheva, ... PloS one 7 (4), e35058, 2012 | 54 | 2012 |
AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis J Park, M Schlederer, M Schreiber, R Ice, O Merkel, M Bilban, S Hofbauer, ... Oncotarget 6 (24), 20697, 2015 | 48 | 2015 |
NEDD9 depletion destabilizes Aurora A kinase and heightens the efficacy of Aurora A inhibitors: implications for treatment of metastatic solid tumors RJ Ice, SL McLaughlin, RH Livengood, MV Culp, ER Eddy, AV Ivanov, ... Cancer research 73 (10), 3168-3180, 2013 | 47 | 2013 |