Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric … JN Kochenderfer, ME Dudley, SH Kassim, RPT Somerville, RO Carpenter, ... Journal of clinical oncology 33 (6), 540-549, 2015 | 1925 | 2015 |
Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia JA Fraietta, SF Lacey, EJ Orlando, I Pruteanu-Malinici, M Gohil, S Lundh, ... Nature medicine 24 (5), 563-571, 2018 | 1411 | 2018 |
A pilot trial using lymphocytes genetically engineered with an NY-ESO-1–reactive T-cell receptor: long-term follow-up and correlates with response PF Robbins, SH Kassim, TLN Tran, JS Crystal, RA Morgan, SA Feldman, ... Clinical Cancer Research 21 (5), 1019-1027, 2015 | 887 | 2015 |
Donor-derived CD19-targeted T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation JN Kochenderfer, ME Dudley, RO Carpenter, SH Kassim, JJ Rose, ... Blood, The Journal of the American Society of Hematology 122 (25), 4129-4139, 2013 | 702 | 2013 |
Tumor-infiltrating lymphocytes genetically engineered with an inducible gene encoding interleukin-12 for the immunotherapy of metastatic melanoma L Zhang, RA Morgan, JD Beane, Z Zheng, ME Dudley, SH Kassim, ... Clinical cancer research 21 (10), 2278-2288, 2015 | 392 | 2015 |
Characterization of age-related changes in natural killer cells during primary influenza infection in mice S Nogusa, BW Ritz, SH Kassim, SR Jennings, EM Gardner Mechanisms of ageing and development 129 (4), 223-230, 2008 | 147 | 2008 |
In vivo ablation of CD11c-positive dendritic cells increases susceptibility to herpes simplex virus type 1 infection and diminishes NK and T-cell responses SH Kassim, NK Rajasagi, X Zhao, R Chervenak, SR Jennings Journal of virology 80 (8), 3985-3993, 2006 | 146 | 2006 |
Single-cell multiplexed cytokine profiling of CD19 CAR-T cells reveals a diverse landscape of polyfunctional antigen-specific response Q Xue, E Bettini, P Paczkowski, C Ng, A Kaiser, T McConnell, O Kodrasi, ... Journal for immunotherapy of cancer 5, 1-16, 2017 | 121 | 2017 |
Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis SH Kassim, H Li, LH Vandenberghe, C Hinderer, P Bell, D Marchadier, ... PloS one 5 (10), e13424, 2010 | 98 | 2010 |
Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial … SH Kassim, H Li, P Bell, S Somanathan, W Lagor, F Jacobs, J Billheimer, ... Human gene therapy 24 (1), 19-26, 2013 | 90 | 2013 |
CD4+ T Cells Are Required for the Priming of CD8+ T Cells following Infection with Herpes Simplex Virus Type 1 NK Rajasagi, SH Kassim, CM Kollias, X Zhao, R Chervenak, SR Jennings Journal of virology 83 (10), 5256-5268, 2009 | 66 | 2009 |
Biodistribution of AAV8 vectors expressing human low-density lipoprotein receptor in a mouse model of homozygous familial hypercholesterolemia SJ Chen, J Sanmiguel, M Lock, D McMenamin, C Draper, MP Limberis, ... Human Gene Therapy Clinical Development 24 (4), 154-160, 2013 | 48 | 2013 |
Dendritic cells are required for optimal activation of natural killer functions following primary infection with herpes simplex virus type 1 SH Kassim, NK Rajasagi, BW Ritz, SB Pruett, EM Gardner, R Chervenak, ... Journal of virology 83 (7), 3175-3186, 2009 | 45 | 2009 |
Chimeric antigen receptor therapy characterization assays and uses thereof S Kassim, Q Xue US Patent App. 16/381,784, 2020 | 27 | 2020 |
The role of religion in the generation of suicide bombers SH Kassim Brief Treatment and crisis intervention 8 (2), 204, 2008 | 25 | 2008 |
Effective treatment of chemotherapy-refractory diffuse large B-cell lymphoma with autologous T cells genetically-engineered to express an anti-CD19 chimeric antigen receptor JN Kochenderfer, ME Dudley, SH Kassim, RO Carpenter, JC Yang, ... Blood 122 (21), 168, 2013 | 20 | 2013 |
Gene therapy for dyslipidemia: a review of gene replacement and gene inhibition strategies SH Kassim, JM Wilson, DJ Rader Clinical Lipidology 5 (6), 793-809, 2010 | 20 | 2010 |
Toward an integrated model of product characterization for CAR-T cell therapy drug development efforts S Kassim Immuno-oncology Insights, 2017 | 16 | 2017 |
Donor-derived anti-CD19 chimeric-antigen-receptor-expressing T cells cause regression of malignancy persisting after allogeneic hematopoietic stem cell transplantation JN Kochenderfer, ME Dudley, RO Carpenter, SH Kassim, JJ Rose, ... Blood 122 (21), 151, 2013 | 16 | 2013 |
Author Correction: Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia. JA Fraietta, SF Lacey, EJ Orlando, I Pruteanu-Malinici, M Gohil, S Lundh, ... Nature Medicine 27 (3), 561-562, 2021 | 15 | 2021 |