| Cholangiocarcinoma 2020: the next horizon in mechanisms and management JM Banales, JJG Marin, A Lamarca, PM Rodrigues, SA Khan, LR Roberts, ... Nature reviews Gastroenterology & hepatology 17 (9), 557-588, 2020 | 1632 | 2020 |
| Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia AI Masyuk, BQ Huang, CJ Ward, SA Gradilone, JM Banales, TV Masyuk, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 299 (4 …, 2010 | 336 | 2010 |
| Cholangiocyte cilia express TRPV4 and detect changes in luminal tonicity inducing bicarbonate secretion SA Gradilone, AI Masyuk, PL Splinter, JM Banales, BQ Huang, PS Tietz, ... Proceedings of the National Academy of Sciences 104 (48), 19138-19143, 2007 | 255 | 2007 |
| The water channel aquaporin-8 is mainly intracellular in rat hepatocytes, and its plasma membrane insertion is stimulated by cyclic AMP F Garcı́a, A Kierbel, MC Larocca, SA Gradilone, P Splinter, NF LaRusso, ... Journal of Biological Chemistry 276 (15), 12147-12152, 2001 | 247 | 2001 |
| HDAC6 inhibition restores ciliary expression and decreases tumor growth SA Gradilone, BN Radtke, PS Bogert, BQ Huang, GB Gajdos, ... Cancer research 73 (7), 2259-2270, 2013 | 234 | 2013 |
| Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors AI Masyuk, SA Gradilone, JM Banales, BQ Huang, TV Masyuk, SO Lee, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 295 (4 …, 2008 | 191 | 2008 |
| Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling AI Masyuk, BQ Huang, BN Radtke, GB Gajdos, PL Splinter, TV Masyuk, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 304 (11 …, 2013 | 166 | 2013 |
| The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD) JM Banales, TV Masyuk, SA Gradilone, AI Masyuk, JF Medina, ... Hepatology 49 (1), 160-174, 2009 | 139 | 2009 |
| Pasireotide is more effective than octreotide in reducing hepatorenal cystogenesis in rodents with polycystic kidney and liver diseases TV Masyuk, BN Radtke, AJ Stroope, JM Banales, SA Gradilone, B Huang, ... Hepatology 58 (1), 409-421, 2013 | 135 | 2013 |
| Glucagon induces the plasma membrane insertion of functional aquaporin-8 water channels in isolated rat hepatocytes SA Gradilone, F Garcıa, RC Huebert, PS Tietz, MC Larocca, A Kierbel, ... Hepatology 37 (6), 1435-1441, 2003 | 117 | 2003 |
| SOX17 regulates cholangiocyte differentiation and acts as a tumor suppressor in cholangiocarcinoma M Merino-Azpitarte, E Lozano, MJ Perugorria, A Esparza-Baquer, O Erice, ... Journal of hepatology 67 (1), 72-83, 2017 | 105 | 2017 |
| Activation of Trpv4 reduces the hyperproliferative phenotype of cystic cholangiocytes from an animal model of ARPKD SA Gradilone, TV Masyuk, BQ Huang, JM Banales, GL Lehmann, ... Gastroenterology 139 (1), 304-314. e2, 2010 | 103 | 2010 |
| Non-canonical Hedgehog signaling contributes to chemotaxis in cholangiocarcinoma N Razumilava, SA Gradilone, RL Smoot, JC Mertens, SF Bronk, AE Sirica, ... Journal of hepatology 60 (3), 599-605, 2014 | 94 | 2014 |
| Aquaporin water channels in central nervous system GL Lehmann, SA Gradilone, RA Marinelli Current neurovascular research 1 (4), 293-303, 2004 | 94 | 2004 |
| LPS induces the TNF-α-mediated downregulation of rat liver aquaporin-8: Role in sepsis-associated cholestasis GL Lehmann, FI Carreras, LR Soria, SA Gradilone, RA Marinelli American Journal of Physiology-Gastrointestinal and Liver Physiology 294 (2 …, 2008 | 93 | 2008 |
| Hepatic cystogenesis is associated with abnormal expression and location of ion transporters and water channels in an animal model of autosomal recessive polycystic kidney disease JM Banales, TV Masyuk, PS Bogert, BQ Huang, SA Gradilone, SO Lee, ... The American journal of pathology 173 (6), 1637-1646, 2008 | 88 | 2008 |
| Rat hepatocyte aquaporin‐8 water channels are down‐regulated in extrahepatic cholestasis FI Carreras, SA Gradilone, A Mazzone, F García, BQ Huang, JE Ochoa, ... Hepatology 37 (5), 1026-1033, 2003 | 87 | 2003 |
| The cholangiocyte primary cilium in health and disease AP Mansini, E Peixoto, KM Thelen, C Gaspari, S Jin, SA Gradilone Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (4 …, 2018 | 71 | 2018 |
| Role of histone deacetylases in carcinogenesis: potential role in cholangiocarcinoma K Pant, E Peixoto, S Richard, SA Gradilone Cells 9 (3), 780, 2020 | 68 | 2020 |
| MicroRNA (miR)‐433 and miR‐22 dysregulations induce histone‐deacetylase‐6 overexpression and ciliary loss in cholangiocarcinoma AP Mansini, MJ Lorenzo Pisarello, KM Thelen, M Cruz‐Reyes, E Peixoto, ... Hepatology 68 (2), 561-573, 2018 | 67 | 2018 |
