The role of mucus on drug transport and its potential to affect therapeutic outcomes X Murgia, B Loretz, O Hartwig, M Hittinger, CM Lehr Advanced drug delivery reviews 124, 82-97, 2018 | 264 | 2018 |
Size-limited penetration of nanoparticles into porcine respiratory mucus after aerosol deposition X Murgia, P Pawelzyk, UF Schaefer, C Wagner, N Willenbacher, CM Lehr Biomacromolecules 17 (4), 1536-1542, 2016 | 139 | 2016 |
Cannabidiol reduces brain damage and improves functional recovery after acute hypoxia-ischemia in newborn pigs H Lafuente, FJ Alvarez, MR Pazos, A Alvarez, MC Rey-Santano, V Mielgo, ... Pediatric research 70 (3), 272-277, 2011 | 116 | 2011 |
Challenges and strategies in drug delivery systems for treatment of pulmonary infections DK Ho, BLB Nichols, KJ Edgar, X Murgia, B Loretz, CM Lehr European journal of pharmaceutics and biopharmaceutics 144, 110-124, 2019 | 114 | 2019 |
Overcoming the pulmonary barrier: New insights to improve the efficiency of inhaled therapeutics X Murgia, C de Souza Carvalho, CM Lehr European Journal of Nanomedicine 6 (3), 157-169, 2014 | 66 | 2014 |
Kinetics of mRNA delivery and protein translation in dendritic cells using lipid-coated PLGA nanoparticles H Yasar, A Biehl, C De Rossi, M Koch, X Murgia, B Loretz, CM Lehr Journal of nanobiotechnology 16, 1-19, 2018 | 61 | 2018 |
Macro-and microrheological properties of mucus surrogates in comparison to native intestinal and pulmonary mucus BC Huck, O Hartwig, A Biehl, K Schwarzkopf, C Wagner, B Loretz, ... Biomacromolecules 20 (9), 3504-3512, 2019 | 55 | 2019 |
In vitro and in vivo comparison between poractant alfa and the new generation synthetic surfactant CHF5633 F Ricci, X Murgia, R Razzetti, N Pelizzi, F Salomone Pediatric research 81 (2), 369-375, 2017 | 53 | 2017 |
Human airway mucus alters susceptibility of Pseudomonas aeruginosa biofilms to tobramycin, but not colistin L Müller, X Murgia, L Siebenbürger, C Börger, K Schwarzkopf, K Sewald, ... Journal of Antimicrobial Chemotherapy 73 (10), 2762-2769, 2018 | 51 | 2018 |
Squalenyl hydrogen sulfate nanoparticles for simultaneous delivery of tobramycin and an alkylquinolone quorum sensing inhibitor enable the eradication of P. aeruginosa biofilm … DK Ho, X Murgia, C De Rossi, R Christmann, AG Hüfner de Mello Martins, ... Angewandte Chemie 132 (26), 10378-10382, 2020 | 48 | 2020 |
From bench to bedside: in vitro and in vivo evaluation of a neonate-focused nebulized surfactant delivery strategy F Bianco, F Ricci, C Catozzi, X Murgia, M Schlun, A Bucholski, U Hetzer, ... Respiratory research 20, 1-11, 2019 | 44 | 2019 |
A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms C Schütz, DK Ho, MM Hamed, AS Abdelsamie, T Röhrig, C Herr, AM Kany, ... Advanced Science 8 (12), 2004369, 2021 | 42 | 2021 |
Aerosol drug delivery to spontaneously-breathing preterm neonates: lessons learned F Bianco, F Salomone, I Milesi, X Murgia, S Bonelli, E Pasini, R Dellacà, ... Respiratory Research 22, 1-31, 2021 | 41 | 2021 |
Farnesylated glycol chitosan as a platform for drug delivery: Synthesis, characterization, and investigation of mucus–particle interactions DK Ho, S Frisch, A Biehl, E Terriac, C De Rossi, K Schwarzkopf, ... Biomacromolecules 19 (8), 3489-3501, 2018 | 40 | 2018 |
Acute and sustained effects of aerosolized vs. bolus surfactant therapy in premature lambs with respiratory distress syndrome C Rey-Santano, VE Mielgo, L Andres, E Ruiz-del-Yerro, A Valls-i-Soler, ... Pediatric ReseaRCh 73 (5), 639-646, 2013 | 40 | 2013 |
In vitro and in vivo characterization of poractant alfa supplemented with budesonide for safe and effective intratracheal administration F Ricci, C Catozzi, F Ravanetti, X Murgia, F D'Aló, N Macchidani, E Sgarbi, ... Pediatric research 82 (6), 1056-1063, 2017 | 38 | 2017 |
Modelling the bronchial barrier in pulmonary drug delivery: a human bronchial epithelial cell line supplemented with human tracheal mucus X Murgia, H Yasar, C Carvalho-Wodarz, B Loretz, S Gordon, ... European Journal of Pharmaceutics and Biopharmaceutics 118, 79-88, 2017 | 38 | 2017 |
Tracing molecular and structural changes upon mucolysis with N-acetyl cysteine in human airway mucus B Vukosavljevic, X Murgia, K Schwarzkopf, UF Schaefer, CM Lehr, ... International Journal of Pharmaceutics 533 (2), 373-376, 2017 | 31 | 2017 |
In Vitro Model of the Gram-Negative Bacterial Cell Envelope for Investigation of Anti-Infective Permeation Kinetics F Graef, R Richter, V Fetz, X Murgia, C De Rossi, N Schneider-Daum, ... ACS infectious diseases 4 (8), 1188-1196, 2018 | 27 | 2018 |
Cerebral and lung effects of a new generation synthetic surfactant with SP‐B and SP‐C analogs in preterm lambs C Rey‐Santano, VE Mielgo, X Murgia, MA Gomez‐Solaetxe, F Salomone, ... Pediatric pulmonology 52 (7), 929-938, 2017 | 27 | 2017 |