| Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation R Nagase, D Inoue, A Pastore, T Fujino, HA Hou, N Yamasaki, S Goyama, ... Journal of Experimental Medicine 215 (6), 1729-1747, 2018 | 145 | 2018 |
| The role of ASXL1 in hematopoiesis and myeloid malignancies S Asada, T Fujino, S Goyama, T Kitamura Cellular and molecular life sciences 76, 2511-2523, 2019 | 116 | 2019 |
| Mutant ASXL1 cooperates with BAP1 to promote myeloid leukaemogenesis S Asada, S Goyama, D Inoue, S Shikata, R Takeda, T Fukushima, ... Nature communications 9 (1), 2733, 2018 | 114 | 2018 |
| Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway T Fujino, S Goyama, Y Sugiura, D Inoue, S Asada, S Yamasaki, ... Nature communications 12 (1), 1826, 2021 | 73 | 2021 |
| Clonal hematopoiesis and associated diseases: A review of recent findings S Asada, T Kitamura Cancer science 112 (10), 3962-3971, 2021 | 61 | 2021 |
| Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia Y Hayashi, S Goyama, XX Liu, M Tamura, S Asada, Y Tanaka, ... Nature communications 10 (1), 4869, 2019 | 44 | 2019 |
| Discrimination of dormant and active hematopoietic stem cells by G0 marker reveals dormancy regulation by cytoplasmic calcium T Fukushima, Y Tanaka, FK Hamey, CH Chang, T Oki, S Asada, ... Cell Reports 29 (12), 4144-4158. e7, 2019 | 37 | 2019 |
| Aberrant histone modifications induced by mutant ASXL1 in myeloid neoplasms S Asada, T Kitamura International Journal of Hematology 110, 179-186, 2019 | 32 | 2019 |
| The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1–RUNX1T1 T Yonezawa, H Takahashi, S Shikata, X Liu, M Tamura, S Asada, ... Journal of Biological Chemistry 292 (30), 12528-12541, 2017 | 23 | 2017 |
| A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells K Yamamoto, S Goyama, S Asada, T Fujino, T Yonezawa, N Sato, ... Cell reports 36 (8), 2021 | 19 | 2021 |
| CHIP‐associated mutant ASXL1 in blood cells promotes solid tumor progression X Liu, N Sato, Y Shimosato, TW Wang, T Denda, YH Chang, T Yabushita, ... Cancer Science 113 (4), 1182-1194, 2022 | 18 | 2022 |
| MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis Y Hayashi, KC Kawabata, Y Tanaka, Y Uehara, Y Mabuchi, K Murakami, ... Cell reports 39 (6), 2022 | 17 | 2022 |
| Eliminating chronic myeloid leukemia stem cells by IRAK1/4 inhibitors Y Tanaka, R Takeda, T Fukushima, K Mikami, S Tsuchiya, M Tamura, ... Nature Communications 13 (1), 271, 2022 | 17 | 2022 |
| Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia T Isobe, M Takagi, A Sato-Otsubo, A Nishimura, G Nagae, C Yamagishi, ... Nature communications 13 (1), 4501, 2022 | 15 | 2022 |
| HHEX promotes myeloid transformation in cooperation with mutant ASXL1 R Takeda, S Asada, SJ Park, A Yokoyama, HJ Becker, A Kanai, ... Blood, The Journal of the American Society of Hematology 136 (14), 1670-1684, 2020 | 15 | 2020 |
| Opposing effects of acute versus chronic inhibition of p53 on decitabine’s efficacy in myeloid neoplasms M Tamura, T Yonezawa, X Liu, S Asada, Y Hayashi, T Fukuyama, ... Scientific Reports 9 (1), 8171, 2019 | 11 | 2019 |
| Novel working hypothesis for pathogenesis of hematological malignancies: combination of mutations-induced cellular phenotypes determines the disease (cMIP-DD) T Kitamura, N Watanabe-Okochi, Y Enomoto, F Nakahara, T Oki, ... The journal of biochemistry 159 (1), 17-25, 2016 | 11 | 2016 |
| IMPDH inhibition activates TLR‐VCAM1 pathway and suppresses the development of MLL‐fusion leukemia X Liu, N Sato, T Yabushita, J Li, Y Jia, M Tamura, S Asada, T Fujino, ... EMBO Molecular Medicine 15 (1), e15631, 2023 | 10 | 2023 |
| High expression of ABCG2 induced by EZH2 disruption has pivotal roles in MDS pathogenesis KC Kawabata, Y Hayashi, D Inoue, H Meguro, H Sakurai, T Fukuyama, ... Leukemia 32 (2), 419-428, 2018 | 10 | 2018 |
| Mechanisms involved in hematopoietic stem cell aging T Fujino, S Asada, S Goyama, T Kitamura Cellular and Molecular Life Sciences 79 (9), 473, 2022 | 8 | 2022 |
