A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities T Klymenko, B Papp, W Fischle, T Köcher, M Schelder, C Fritsch, B Wild, ... Genes & development 20 (9), 1110-1122, 2006 | 498 | 2006 |
Pcl‐PRC2 is needed to generate high levels of H3‐K27 trimethylation at Polycomb target genes M Nekrasov, T Klymenko, S Fraterman, B Papp, K Oktaba, T Köcher, ... The EMBO journal 26 (18), 4078-4088, 2007 | 329 | 2007 |
The histone methyltransferases Trithorax and Ash1 prevent transcriptional silencing by Polycomb group proteins T Klymenko, J Müller EMBO reports 5 (4), 373-377, 2004 | 316 | 2004 |
Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cells A Ivanov, SA Beers, CA Walshe, J Honeychurch, W Alduaij, KL Cox, ... The Journal of clinical investigation 119 (8), 2143-2159, 2009 | 234 | 2009 |
NXF1/p15 heterodimers are essential for mRNA nuclear export in Drosophila A HEROLD, T KLYMENKO, E IZAURRALDE Rna 7 (12), 1768-1780, 2001 | 226 | 2001 |
Up-regulation of the embryonic self-renewal network through reversible polyploidy in irradiated p53-mutant tumour cells K Salmina, E Jankevics, A Huna, D Perminov, I Radovica, T Klymenko, ... Experimental cell research 316 (13), 2099-2112, 2010 | 127 | 2010 |
RNA-Seq analysis of differentiated keratinocytes reveals a massive response to late events during human papillomavirus 16 infection, including loss of epithelial barrier function T Klymenko, Q Gu, I Herbert, A Stevenson, V Iliev, G Watkins, C Pollock, ... Journal of virology 91 (24), 10.1128/jvi. 01001-17, 2017 | 55 | 2017 |
Human papillomavirus E2 regulates SRSF3 (SRp20) to promote capsid protein expression in infected differentiated keratinocytes T Klymenko, H Hernandez-Lopez, AI MacDonald, JM Bodily, SV Graham Journal of Virology 90 (10), 5047-5058, 2016 | 40 | 2016 |
The novel Bcl-2 inhibitor ABT-737 is more effective in hypoxia and is able to reverse hypoxia-induced drug resistance in neuroblastoma cells T Klymenko, M Brandenburg, C Morrow, C Dive, G Makin Molecular cancer therapeutics 10 (12), 2373-2383, 2011 | 39 | 2011 |
Structure of an atypical Tudor domain in the Drosophila Polycomblike protein A Friberg, A Oddone, T Klymenko, J Müller, M Sattler Protein Science 19 (10), 1906-1916, 2010 | 28 | 2010 |
Lamin B1 regulates somatic mutations and progression of B-cell malignancies T Klymenko, J Bloehdorn, J Bahlo, S Robrecht, G Akylzhanova, K Cox, ... Leukemia 32 (2), 364-375, 2018 | 22 | 2018 |
Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia J Bloehdorn, A Braun, A Taylor-Weiner, BMC Jebaraj, S Robrecht, ... Nature Communications 12 (1), 5395, 2021 | 20 | 2021 |
Natural NS3 resistance polymorphisms occur frequently prior to treatment in HIV-positive patients with acute hepatitis C M Leggewie, VB Sreenu, T Abdelrahman, ECM Leitch, GS Wilkie, ... Aids 27 (15), 2485-2488, 2013 | 18 | 2013 |
Human papillomavirus gene expression is controlled by host cell splicing factors T Klymenko, SV Graham Biochemical Society Transactions 40 (4), 773-777, 2012 | 17 | 2012 |
Generation of monoclonal antibody targeting fibroblast growth factor receptor 3 O Gorbenko, G Ovcharenko, T Klymenko, O Zhyvoloup, N Gaman, ... Hybridoma 28 (4), 295-300, 2009 | 17 | 2009 |
Rituximab and obinutuzumab differentially hijack the B cell receptor and NOTCH1 signaling pathways J Edelmann, AD Dokal, E Vilventhraraja, K Holzmann, D Britton, ... Iscience 24 (2), 2021 | 14 | 2021 |
Preclinical efficacy of the bioreductive alkylating agent RH1 against paediatric tumours D Hussein, SV Holt, KE Brookes, T Klymenko, JK Adamski, A Hogg, ... British journal of cancer 101 (1), 55-63, 2009 | 13 | 2009 |
Reduction of Mitochondrial Membrane Potential Leads to Enhancement of Type-II CD20-Antibody Cytotoxicity in Diffuse Large B-Cell Lymphoma E Vilventhraraja, T Klymenko, J Edelmann, J Gribben, A Ivanov Blood 128 (22), 1763, 2016 | 2 | 2016 |
Stromal cell inhibition of anti-CD20 antibody mediated killing of B-cell malignancies E Fagnano, S Pendharkar, M Colton, PN Jones, MC Sallan, T Klymenko, ... Frontiers in Cell and Developmental Biology 11, 1270398, 2023 | 1 | 2023 |
Multiplatform Profiling Characterizes Functional Networks in Genomically Stable and Instable Chronic Lymphocytic Leukemia J Bloehdorn, A Braun, BMC Jebaraj, A Taylor-Weiner, S Robrecht, ... Blood 136, 12-13, 2020 | | 2020 |