| Subclone-specific microenvironmental impact and drug response in refractory multiple myeloma revealed by single‐cell transcriptomics SM Tirier, JP Mallm, S Steiger, AM Poos, MHS Awwad, N Giesen, ... Nature Communications 12 (1), 6960, 2021 | 85 | 2021 |
| The pre-existing T cell landscape determines the response to bispecific T cell engagers in multiple myeloma patients MJ Friedrich, P Neri, N Kehl, J Michel, S Steiger, M Kilian, N Leblay, ... Cancer Cell 41 (4), 711-725. e6, 2023 | 76 | 2023 |
| Pheno-seq–linking visual features and gene expression in 3D cell culture systems SM Tirier, J Park, F Preußer, L Amrhein, Z Gu, S Steiger, JP Mallm, ... Scientific reports 9 (1), 12367, 2019 | 22 | 2019 |
| Resolving therapy resistance mechanisms in multiple myeloma by multiomics subclone analysis AM Poos, N Prokoph, MJ Przybilla, JP Mallm, S Steiger, I Seufert, L John, ... Blood 142 (19), 1633-1646, 2023 | 14 | 2023 |
| Local emergence and decline of a SARS-CoV-2 variant with mutations L452R and N501Y in the spike protein JP Mallm, C Bundschuh, H Kim, N Weidner, S Steiger, I Lander, K Börner, ... Medrxiv, 2021.04. 27.21254849, 2021 | 14 | 2021 |
| Resolving the spatial architecture of myeloma and its microenvironment at the single-cell level L John, AM Poos, A Brobeil, C Schinke, S Huhn, N Prokoph, R Lutz, ... Nature Communications 14 (1), 5011, 2023 | 9 | 2023 |
| Dissection of gastric homeostasis in vivo facilitates permanent capture of isthmus-like stem cells in vitro AJ Huebner, RA Gorelov, R Deviatiiarov, S Demharter, T Kull, RM Walsh, ... Nature Cell Biology 25 (3), 390-403, 2023 | 7 | 2023 |
| IgE type multiple myeloma exhibits hypermutated phenotype and tumor reactive T cells N Kehl, M Kilian, J Michel, TR Wagner, S Uhrig, A Brobeil, LS Sester, ... Journal for Immunotherapy of Cancer 10 (10), 2022 | 6 | 2022 |
| Bone marrow immune signatures in multiple myeloma are linked to tumor heterogeneity and treatment outcome S Steiger, R Lutz, N Prokoph, S Palit, SM Tirier, P Reichert, A Baumann, ... Blood 140 (Supplement 1), 2083-2085, 2022 | 4 | 2022 |
| The spatial heterogeneity in newly diagnosed multiple myeloma patients-from sub-clonal architecture to the immune microenvironment L John, A Poos, SM Tirier, JP Mallm, N Prokoph, A Brobeil, R Lutz, ... Blood 138, 729, 2021 | 3 | 2021 |
| pagoda2: A package for analyzing and interactively exploring large single-cell RNA-seq datasets N Barkas, B Joyce, P Kharchenko, S Steiger, J Fan, K Slowikowski GitHub https://github. com/hms-dbmi/pagoda2, 2018 | 3 | 2018 |
| Evolution of SARS-CoV-2 in the Rhine-Neckar/Heidelberg Region 01/2021–07/2023 C Bundschuh, N Weidner, J Klein, T Rausch, N Azevedo, A Telzerow, ... Infection, Genetics and Evolution 119, 105577, 2024 | 2 | 2024 |
| OAB-002: The preexisting T cell landscape determines response to T cell-engagers therapy in multiple myeloma M Friedrich, N Kehl, P Neri, J Michel, N Leblay, R Maity, M Kilian, H Lee, ... Clinical Lymphoma Myeloma and Leukemia 22, S1-S2, 2022 | 1 | 2022 |
| Identification of tumor-reactive T cell receptors through functional single cell interaction analyses for personalized T cell therapy TR Wagner, N Kehl, S Steiger, M Kilian, B Schönfelder, T Boschert, ... Cancer Research 84 (6_Supplement), 14-14, 2024 | | 2024 |
| Tumor Reactive T Cells Reside in the Bone Marrow and Are Associated with Clinical Response to Hematological Malignancies TR Wagner, N Kehl, S Steiger, M Kilian, K Foster, T Boschert, ... Blood 142, 4074, 2023 | | 2023 |
| Progenitor-like cell type of an MLL-EDC4 fusion in acute myeloid leukemia LC Schuster, AP Syed, SM Tirier, S Steiger, I Seufert, H Becker, ... Blood Advances 7 (22), 7079-7083, 2023 | | 2023 |
| P-220 Discovery of tumor-reactive T cell receptors by functional single cell interaction analyses in patients with newly diagnosed multiple myeloma T Wagner, N Kehl, S Steiger, M Kilian, T Boschert, K Lindner, ... Clinical Lymphoma Myeloma and Leukemia 23, S156, 2023 | | 2023 |
| OA-23 Resolving therapy resistance mechanisms in multiple myeloma by multi-omics subclone analysis A Poos, N Prokoph, M Przybilla, JP Mallm, S Steiger, I Seufert, L John, ... Clinical Lymphoma Myeloma and Leukemia 23, S14-S15, 2023 | | 2023 |
| Discovery of Tumor Reactive T Cell Receptors in Newly Diagnosed Multiple Myeloma M Friedrich, N Kehl, S Steiger, TR Wagner, K Lindner, M Kilian, J Michel, ... Blood 140 (Supplement 1), 604-605, 2022 | | 2022 |
| Single-Cell Multi-Omics Reveal Longitudinal Dynamics of Clonal Architecture and Microenvironment Interactions in Relapsed-Refractory Myeloma AM Poos, N Prokoph, MJ Przybilla, JP Mallm, S Steiger, I Lander, L John, ... Blood 140 (Supplement 1), 9987-9988, 2022 | | 2022 |
Marc S. RaabDeutsches Krebsforschungszentrum在 dkfz-heidelberg.de 的电子邮件经过验证
