Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice M Komatsu, S Waguri, M Koike, Y Sou, T Ueno, T Hara, N Mizushima, ... Cell 131 (6), 1149-1163, 2007 | 2391 | 2007 |
A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans A Kitamura, Y Maekawa, H Uehara, K Izumi, I Kawachi, M Nishizawa, ... The Journal of clinical investigation 121 (10), 4150-4160, 2011 | 326 | 2011 |
A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes J Hamazaki, S Iemura, T Natsume, H Yashiroda, K Tanaka, S Murata The EMBO journal 25 (19), 4524-4536, 2006 | 296 | 2006 |
Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process A Tonoki, E Kuranaga, T Tomioka, J Hamazaki, S Murata, K Tanaka, ... Molecular and cellular biology 29 (4), 1095-1106, 2009 | 295 | 2009 |
Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones T Kaneko, J Hamazaki, S Iemura, K Sasaki, K Furuyama, T Natsume, ... Cell 137 (5), 914-925, 2009 | 226 | 2009 |
The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction S Koizumi, T Irie, S Hirayama, Y Sakurai, H Yashiroda, I Naguro, H Ichijo, ... Elife 5, e18357, 2016 | 185 | 2016 |
17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse K Tokui, H Adachi, M Waza, M Katsuno, M Minamiyama, H Doi, K Tanaka, ... Human molecular genetics 18 (5), 898-910, 2009 | 137 | 2009 |
Rpn10-mediated degradation of ubiquitinated proteins is essential for mouse development J Hamazaki, K Sasaki, H Kawahara, S Hisanaga, K Tanaka, S Murata Molecular and cellular biology 27 (19), 6629-6638, 2007 | 120 | 2007 |
Crystal structure of the de-ubiquitinating enzyme UCH37 (human UCH-L5) catalytic domain K Nishio, SW Kim, K Kawai, T Mizushima, T Yamane, J Hamazaki, ... Biochemical and biophysical research communications 390 (3), 855-860, 2009 | 82 | 2009 |
Redundant roles of Rpn10 and Rpn13 in recognition of ubiquitinated proteins and cellular homeostasis J Hamazaki, S Hirayama, S Murata PLoS genetics 11 (7), e1005401, 2015 | 81 | 2015 |
Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets X Lu, U Nowicka, V Sridharan, F Liu, L Randles, D Hymel, M Dyba, ... Nature communications 8 (1), 15540, 2017 | 78 | 2017 |
Characterization of the testis-specific proteasome subunit α4s in mammals H Uechi, J Hamazaki, S Murata Journal of biological chemistry 289 (18), 12365-12374, 2014 | 56 | 2014 |
Foxn1-β5t transcriptional axis controls CD8+ T-cell production in the thymus MM Uddin, I Ohigashi, R Motosugi, T Nakayama, M Sakata, J Hamazaki, ... Nature communications 8 (1), 14419, 2017 | 52 | 2017 |
PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis K Sasaki, J Hamazaki, M Koike, Y Hirano, M Komatsu, Y Uchiyama, ... Molecular and cellular biology, 2010 | 50 | 2010 |
NRF3-POMP-20S proteasome assembly axis promotes cancer development via ubiquitin-independent proteolysis of p53 and retinoblastoma protein T Waku, N Nakamura, M Koji, H Watanabe, H Katoh, C Tatsumi, ... Molecular and cellular biology 40 (10), e00597-19, 2020 | 39 | 2020 |
Transcriptional regulation of the 26S proteasome by Nrf1 S Koizumi, J Hamazaki, S Murata Proceedings of the Japan Academy, Series B 94 (8), 325-336, 2018 | 39 | 2018 |
Sirt1-deficiency causes defective protein quality control T Tomita, J Hamazaki, S Hirayama, MW McBurney, H Yashiroda, ... Scientific reports 5 (1), 12613, 2015 | 37 | 2015 |
Trans-omics impact of thymoproteasome in cortical thymic epithelial cells I Ohigashi, Y Tanaka, K Kondo, S Fujimori, H Kondo, AC Palin, ... Cell reports 29 (9), 2901-2916. e6, 2019 | 36 | 2019 |
ER-resident transcription factor Nrf1 regulates proteasome expression and beyond J Hamazaki, S Murata International journal of molecular sciences 21 (10), 3683, 2020 | 35 | 2020 |
Mouse zygote-specific proteasome assembly chaperone important for maternal-to-zygotic transition SW Shin, N Shimizu, M Tokoro, S Nishikawa, Y Hatanaka, M Anzai, ... Biology Open 2 (2), 170-182, 2012 | 35 | 2012 |