Non-covalent SARS-CoV-2 Mpro inhibitors developed from in silico screen hits GG Rossetti, MA Ossorio, S Rempel, A Kratzel, VS Dionellis, S Barriot, ... Scientific reports 12 (1), 2505, 2022 | 51 | 2022 |
Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells FJ Groelly, RA Dagg, M Petropoulos, GG Rossetti, B Prasad, ... Molecular Cell 82 (18), 3382-3397. e7, 2022 | 27 | 2022 |
RAD51 protects human cells from transcription-replication conflicts R Bhowmick, M Lerdrup, SA Gadi, GG Rossetti, MI Singh, Y Liu, ... Molecular Cell 82 (18), 3366-3381. e9, 2022 | 23 | 2022 |
Transcription–replication conflicts underlie sensitivity to PARP inhibitors M Petropoulos, A Karamichali, GG Rossetti, A Freudenmann, LG Iacovino, ... Nature 628 (8007), 433-441, 2024 | 16 | 2024 |
CMT2A harboring mitofusin 2 mutation with optic nerve atrophy and normal visual acuity S Guerriero, F D’Oria, G Rossetti, RA Favale, S Zoccolella, G Alessio, ... International medical case reports journal, 41-45, 2020 | 12 | 2020 |
A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells RA Dagg, G Zonderland, EP Lombardi, GG Rossetti, FJ Groelly, S Barroso, ... Nature Communications 12 (1), 4919, 2021 | 9 | 2021 |
Genomic instability profiles at the single cell level in mouse colorectal cancers of defined genotypes VS Dionellis, M Norkin, A Karamichali, GG Rossetti, J Huelsken, ... Cancers 13 (6), 1267, 2021 | 5 | 2021 |
Draining the FEN1s for cancer therapy GG Rossetti, SK Sotiriou, TD Halazonetis Proceedings of the National Academy of Sciences 117 (36), 21849-21850, 2020 | 1 | 2020 |
FoRx-06-428 is a novel PARG inhibitor with potent anti-tumor efficacy in preclinical cancer models O Querolle, U Lücking, L Iacovino, A Freudenmann, G Rossetti, M Gysin, ... Cancer Research 84 (6_Supplement), 3366-3366, 2024 | | 2024 |
Transcription–replication conflicts underlie sensitivity to PARP inhibitors SKSTDH Michalis Petropoulos, Angeliki Karamichali, Giacomo G. Rossetti ... DOI: 10.1038/s41586-024-07217-2, 2024 | | 2024 |
Insights into DNA Damage in Regenerating Young and Aged Mouse Livers A Asensio Aldave, N Dommann, G Rossetti, A Karamichali, V Dionellis, ... British Journal of Surgery 110 (Supplement_5), znad178. 007, 2023 | | 2023 |
DNA damage generated by transcription-replication conflicts explains the synthetic lethality of PARP inhibitors with homologous recombination deficiency TD Halazonetis, M Petropoulos, GG Rossetti, A Karamichali, ... Cancer Research 83 (7_Supplement), 1566-1566, 2023 | | 2023 |