CpG islands influence chromatin structure via the CpG-binding protein Cfp1 JP Thomson, PJ Skene, J Selfridge, T Clouaire, J Guy, S Webb, ARW Kerr, ... Nature 464 (7291), 1082-1086, 2010 | 766 | 2010 |
Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration A Raven, WY Lu, TY Man, S Ferreira-Gonzalez, E O’Duibhir, BJ Dwyer, ... Nature 547 (7663), 350-354, 2017 | 492 | 2017 |
Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems CE Nestor, R Ottaviano, D Reinhardt, HA Cruickshanks, HK Mjoseng, ... Genome biology 16, 1-17, 2015 | 187 | 2015 |
Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions A Cole, Thomson, Meehan Genome Biology, 2017 | 178 | 2017 |
Neutrophils fuel effective immune responses through gluconeogenesis and glycogenesis P Sadiku, JA Willson, EM Ryan, D Sammut, P Coelho, ER Watts, ... Cell metabolism 33 (2), 411-423. e4, 2021 | 128 | 2021 |
Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver JP Thomson, JM Hunter, H Lempiäinen, A Müller, R Terranova, JG Moggs, ... Nucleic acids research 41 (11), 5639-5654, 2013 | 97 | 2013 |
DNA methylation directs polycomb-dependent 3D genome re-organization in naive pluripotency K McLaughlin, IM Flyamer, JP Thomson, HK Mjoseng, R Shukla, ... Cell Reports 29 (7), 1974-1985. e6, 2019 | 94 | 2019 |
Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome JP Thomson, H Lempiäinen, JA Hackett, CE Nestor, A Müller, F Bolognani, ... Genome biology 13, 1-17, 2012 | 90 | 2012 |
Loss of Tet1-associated 5-hydroxymethylcytosine is concomitant with aberrant promoter hypermethylation in liver cancer JP Thomson, R Ottaviano, EB Unterberger, H Lempiäinen, A Muller, ... Cancer research 76 (10), 3097-3108, 2016 | 88 | 2016 |
Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome RL Hollis, JP Thomson, B Stanley, M Churchman, AM Meynert, T Rye, ... Nature communications 11 (1), 4995, 2020 | 85 | 2020 |
Identification of Dlk1-Dio3 Imprinted Gene Cluster Noncoding RNAs as Novel Candidate Biomarkers for Liver Tumor Promotion H Lempiäinen, P Couttet, F Bolognani, A Mueller, V Dubost, R Luisier, ... Toxicological sciences 131 (2), 375-386, 2013 | 79 | 2013 |
Hypoxia determines survival outcomes of bacterial infection through HIF-1α–dependent reprogramming of leukocyte metabolism AAR Thompson, RS Dickinson, F Murphy, JP Thomson, HM Marriott, ... Science Immunology 2 (8), eaal2861, 2017 | 75 | 2017 |
Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors R Luisier, H Lempiäinen, N Scherbichler, A Braeuning, M Geissler, ... Toxicological Sciences 139 (2), 501-511, 2014 | 73 | 2014 |
Epigenetic profiles as defined signatures of xenobiotic exposure JP Thomson, JG Moggs, CR Wolf, RR Meehan Mutation Research/Genetic Toxicology and Environmental Mutagenesis 764, 3-9, 2014 | 65 | 2014 |
Epigenetic modification of the PD-1 (Pdcd1) promoter in effector CD4+ T cells tolerized by peptide immunotherapy RC McPherson, JE Konkel, CT Prendergast, JP Thomson, R Ottaviano, ... elife 3, e03416, 2014 | 64 | 2014 |
DNA methylation as a genomic marker of exposure to chemical and environmental agents RR Meehan, JP Thomson, A Lentini, CE Nestor, S Pennings Current opinion in chemical biology 45, 48-56, 2018 | 63 | 2018 |
5-hydroxymethylcytosine profiling as an indicator of cellular state A Laird, JP Thomson, DJ Harrison, RR Meehan Epigenomics 5 (6), 655-669, 2013 | 63 | 2013 |
Comparative analysis of affinity-based 5-hydroxymethylation enrichment techniques JP Thomson, JM Hunter, CE Nestor, DS Dunican, R Terranova, JG Moggs, ... Nucleic acids research 41 (22), e206-e206, 2013 | 62 | 2013 |
The application of genome-wide 5-hydroxymethylcytosine studies in cancer research JP Thomson, RR Meehan Epigenomics 9 (1), 77-91, 2017 | 56 | 2017 |
CpG island chromatin is shaped by recruitment of ZF-CxxC proteins NP Blackledge, JP Thomson, PJ Skene Cold Spring Harbor perspectives in biology 5 (11), a018648, 2013 | 55 | 2013 |