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Pedro Martin-Acosta
Pedro Martin-Acosta
Open Lab Scientist (TCOLF/GSK)
在 gsk.com 的电子邮件经过验证
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Kinetically guided radical-based synthesis of C(sp3)−C(sp3) linkages on DNA
J Wang, H Lundberg, S Asai, P Martín-Acosta, JS Chen, S Brown, ...
Proceedings of the National Academy of Sciences 115 (28), E6404-E6410, 2018
1502018
PROTACs to address the challenges facing small molecule inhibitors
P Martín-Acosta, X Xiao
European journal of medicinal chemistry 210, 112993, 2021
982021
Microwave-Assisted Organocatalytic Intramolecular Knoevenagel/Hetero Diels–Alder Reaction with O-(Arylpropynyloxy)-Salicylaldehydes: Synthesis of Polycyclic …
P Martín-Acosta, G Feresin, A Tapia, A Estévez-Braun
The Journal of Organic Chemistry 81 (20), 9738-9756, 2016
392016
Domino synthesis of embelin derivatives with antibacterial activity
R Peña, P Martín, GE Feresin, A Tapia, F Machín, A Estévez-Braun
Journal of natural products 79 (4), 970-977, 2016
312016
A new family of densely functionalized fused-benzoquinones as potent human protein kinase CK2 inhibitors
P Martin-Acosta, S Haider, A Amesty, D Aichele, J Jose, A Estévez-Braun
European Journal of Medicinal Chemistry 144, 410-423, 2018
212018
Design, synthesis and biological evaluation of new embelin derivatives as CK2 inhibitors
S Oramas-Royo, S Haidar, A Amesty, P Martin-Acosta, G Feresin, A Tapia, ...
Bioorganic Chemistry 95, 103520, 2020
152020
JKST6, a novel multikinase modulator of the BCR-ABL1/STAT5 signaling pathway that potentiates direct BCR-ABL1 inhibition and overcomes imatinib resistance in chronic …
H Aranda-Tavío, C Recio, P Martín-Acosta, M Guerra-Rodríguez, ...
Biomedicine & Pharmacotherapy 144, 112330, 2021
102021
5-Ethynylarylnaphthalimides as antitumor agents: Synthesis and biological evaluation
P Quintana-Espinoza, P Martin-Acosta, Á Amesty, P Martin-Rodriguez, ...
Bioorganic & Medicinal Chemistry 25 (6), 1976-1983, 2017
92017
Synthesis of Quinoline and Dihydroquinoline Embelin Derivatives as Cardioprotective Agents
P Martín-Acosta, I Cuadrado, L González-Cofrade, R Pestano, ...
Journal of Natural Products 86 (2), 317-329, 2023
72023
Modular Synthesis and Antiproliferative Activity of New Dihydro-1H-pyrazolo[1,3-b]pyridine Embelin Derivatives
P Martín-Acosta, Á Amesty, M Guerra-Rodríguez, B Guerra, ...
Pharmaceuticals 14 (10), 1026, 2021
72021
A clickable photoaffinity probe of betulinic acid identifies tropomyosin as a target
P Martín-Acosta, Q Meng, J Klimek, AP Reddy, L David, SK Petrie, BX Li, ...
Acta Pharmaceutica Sinica B 12 (5), 2406-2416, 2022
62022
Efficient multicomponent synthesis of diverse antibacterial embelin-privileged structure conjugates
P Martín-Acosta, R Peña, G Feresin, A Tapia, I Lorenzo-Castrillejo, ...
Molecules 25 (14), 3290, 2020
42020
Mechanistic insights into the activation of ester prodrugs of 666-15
F Xie, P Martín-Acosta, BX Li, X Xiao
Bioorganic & medicinal chemistry letters 30 (19), 127455, 2020
32020
Síntesis dominó de compuestos quinónicos con potencial actividad frente a dianas de interés farmacológico
P Martín Acosta
Síntesis dominó de compuestos quinónicos con potencial actividad frente a …, 2019
22019
Síntesis dominó de compuestos quinónicos con potencial actividad frente a dianas de interés farmacológico
PM Acosta
Universidad de La Laguna, 2019
2019
Design, synthesis and biological evaluation of new embelin derivatives as CK2 Inhibitors
AM Estévez Braun, SM Oramas-Royo, S Haidar, ÁE Amesty Arrieta, ...
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