| 11β-hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5α-reductase yielding 11β-hydroxy-5α-androstanedione AC Swart, L Schloms, KH Storbeck, LM Bloem, T du Toit, JL Quanson, ... The Journal of steroid biochemistry and molecular biology 138, 132-142, 2013 | 109 | 2013 |
| Profiling adrenal 11β-hydroxyandrostenedione metabolites in prostate cancer cells, tissue and plasma: UPC2-MS/MS quantification of 11β-hydroxytestosterone, 11keto-testosterone … T du Toit, LM Bloem, JL Quanson, R Ehlers, AM Serafin, AC Swart The Journal of steroid biochemistry and molecular biology 166, 54-67, 2017 | 78 | 2017 |
| Basics of androgen synthesis and action RN Elzenaty, T du Toit, CE Flück Best Practice & Research Clinical Endocrinology & Metabolism, 101665, 2022 | 62 | 2022 |
| Advances in the analytical methodologies: Profiling steroids in familiar pathways-challenging dogmas LM Bloem, KH Storbeck, P Swart, T du Toit, L Schloms, AC Swart The Journal of steroid biochemistry and molecular biology 153, 80-92, 2015 | 59 | 2015 |
| The 11β-hydroxysteroid dehydrogenase isoforms: pivotal catalytic activities yield potent C11-oxy C19 steroids with 11βHSD2 favouring 11-ketotestosterone, 11-ketoandrostenedione … R Gent, T du Toit, LM Bloem, AC Swart The Journal of Steroid Biochemistry and Molecular Biology 189, 116-126, 2019 | 38 | 2019 |
| Inefficient UGT-conjugation of adrenal 11β-hydroxyandrostenedione metabolites highlights C11-oxy C19 steroids as the predominant androgens in prostate cancer T du Toit, AC Swart Molecular and cellular endocrinology 461, 265-276, 2018 | 37 | 2018 |
| A high-throughput UPC2-MS/MS method for the separation and quantification of C19 and C21 steroids and their C11-oxy steroid metabolites in the classical, alternative, backdoor … T du Toit, MA Stander, AC Swart Journal of Chromatography B 1080, 71-81, 2018 | 28 | 2018 |
| The 11β-hydroxyandrostenedione pathway and C11-oxy C21 backdoor pathway are active in benign prostatic hyperplasia yielding 11keto-testosterone and 11keto-progesterone T du Toit, AC Swart The Journal of Steroid Biochemistry and Molecular Biology 196, 105497, 2020 | 26 | 2020 |
| Back where it belongs: 11β-hydroxyandrostenedione compels the re-assessment of C11-oxy androgens in steroidogenesis L Barnard, T du Toit, AC Swart Molecular and Cellular Endocrinology 525, 111189, 2021 | 21 | 2021 |
| Falsely elevated plasma testosterone concentrations in neonates: importance of LC-MS/MS measurements HM Hamer, MJJ Finken, AE Van Herwaarden, T Du Toit, AC Swart, ... Clinical Chemistry and Laboratory Medicine (CCLM) 56 (6), e141-e143, 2018 | 21 | 2018 |
| What’s in a whisker? High-throughput analysis of twenty-eight C19 and C21 steroids in mammalian whiskers by ultra-performance convergence chromatography-tandem mass spectrometry N Lübcker, LM Bloem, T Du Toit, P Swart, PJN de Bruyn, AC Swart, ... Journal of Chromatography B 1141, 122028, 2020 | 20 | 2020 |
| Steroid hormone analysis of adolescents and young women with polycystic ovarian syndrome and adrenocortical dysfunction using UPC 2-MS/MS AC Swart, T du Toit, E Gourgari, M Kidd, M Keil, FR Faucz, CA Stratakis Pediatric research 89 (1), 118-126, 2021 | 16 | 2021 |
| Parallel targeted and non-targeted quantitative analysis of steroids in human serum and peritoneal fluid by liquid chromatography high-resolution mass spectrometry T Andrieu, T Du Toit, B Vogt, MD Mueller, M Groessl Analytical and bioanalytical chemistry 414 (25), 7461-7472, 2022 | 13 | 2022 |
| Development and function of the fetal adrenal E Pignatti, T Du Toit, CE Flück Reviews in endocrine and metabolic disorders 24 (1), 5-21, 2023 | 12 | 2023 |
| Analysis of 52 C19 and C21 steroids by UPC2-MS/MS: Characterising the C11-oxy steroid metabolome in serum T du Toit, D van Rooyen, MA Stander, SL Atkin, AC Swart Journal of Chromatography B 1152, 122243, 2020 | 11 | 2020 |
| Turning the spotlight on the C11-oxy androgens in human fetal development T du Toit, AC Swart The Journal of Steroid Biochemistry and Molecular Biology 212, 105946, 2021 | 9 | 2021 |
| 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17, 20-lyase to produce … R Gent, T du Toit, AC Swart The Journal of Steroid Biochemistry and Molecular Biology 191, 105369, 2019 | 9 | 2019 |
| C11-oxy C19 and C11-oxy C21 steroids in neonates: UPC2-MS/MS quantification of plasma 11β-hydroxyandrostenedione, 11-ketotestosterone and 11-ketoprogesterone T du Toit, MJJ Finken, HM Hamer, AC Heijboer, AC Swart Steroids 138, 1-5, 2018 | 9 | 2018 |
| The metabolic fate and receptor interaction of 16α-hydroxyprogesterone and its 5α-reduced metabolite, 16α-hydroxy-dihydroprogesterone D van Rooyen, T du Toit, R Louw-du Toit, D Africander, P Swart, AC Swart Molecular and cellular endocrinology 441, 86-98, 2017 | 7 | 2017 |
| Androstenedione Is the Preferred Substrate for Cytochrome P450 11β-hydroxylase Leading to the Production of 11β-Hydroxyandrostenedione in the Adrenal Gland ID Barbier, R Gent, T Du Toit, AC Swart Journal of the Endocrine Society 5 (Suppl 1), A65, 2021 | 4 | 2021 |
