Use of CRISPR/Cas ribonucleoproteins for high throughput gene editing of induced pluripotent stem cells Q Wang, S Chear, K Wing, D Stellon, MTN Tran, J Talbot, A Pébay, ... Methods 194, 18-29, 2021 | 8 | 2021 |
Lysosomal alterations and decreased electrophysiological activity in CLN3 disease patient-derived cortical neurons S Chear, S Perry, R Wilson, A Bindoff, J Talbot, TL Ware, A Grubman, ... Disease Models & Mechanisms 15 (12), dmm049651, 2022 | 6 | 2022 |
CRISPR/Cas-mediated knock-in of genetically encoded fluorescent biosensors into the AAVS1 locus of human-induced pluripotent stem cells D Stellon, MTN Tran, J Talbot, S Chear, MKNM Khalid, A Pébay, ... Induced Pluripotent Stem Cells and Human Disease: Methods and Protocols, 379-398, 2021 | 6 | 2021 |
Image-based quantitation of kainic acid-induced excitotoxicity as a model of neurodegeneration in human iPSC-derived neurons J Talbot, S Chear, A Phipps, A Pébay, AW Hewitt, JC Vickers, AE King, ... Induced Pluripotent Stem Cells and Human Disease: Methods and Protocols, 187-207, 2021 | 4 | 2021 |
Bioactivity profiles of cytoprotective short-chain quinones Z Feng, M Nadikudi, KL Woolley, AL Hemasa, S Chear, JA Smith, ... Molecules 26 (5), 1382, 2021 | 2 | 2021 |
Genetic and cellular basis of impaired phagocytosis and photoreceptor degeneration in CLN3 disease J Han, S Chear, J Talbot, V Swier, C Booth, C Reuben-Thomas, S Dalvi, ... bioRxiv, 2024.06. 09.597388, 2024 | | 2024 |
Investigating photoreceptor outer segment phagocytosis by retinal pigment epithelium in CLN3-Batten J Han, KA White, S Chear, J Talbot, W Spencer, CI Thomas, VS Mosher, ... Investigative Ophthalmology & Visual Science 63 (7), 2442–F0386-2442–F0386, 2022 | | 2022 |
Lysosomal alterations and decreased electrophysiological activity in CLN3 disease (966 bp deletion, E295K) patient-derived cortical neurons S Chear, S Perry, R Wilson, A Bindoff, J Talbot, TL Ware, A Grubman, ... bioRxiv, 2022.04. 28.489465, 2022 | | 2022 |
A patient-specific stem cell model of Batten disease S Chear University Of Tasmania, 2022 | | 2022 |