Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR AC Calkin, P Tontonoz Nature reviews Molecular cell biology 13 (4), 213-224, 2012 | 805 | 2012 |
Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail D Brasacchio, J Okabe, C Tikellis, A Balcerczyk, P George, EK Baker, ... Diabetes 58 (5), 1229-1236, 2009 | 601 | 2009 |
Receptor for advanced glycation end products (RAGE) deficiency attenuates the development of atherosclerosis in diabetes A Soro-Paavonen, AMD Watson, J Li, K Paavonen, A Koitka, AC Calkin, ... Diabetes 57 (9), 2461-2469, 2008 | 498 | 2008 |
Liver x receptor signaling pathways and atherosclerosis AC Calkin, P Tontonoz Arteriosclerosis, thrombosis, and vascular biology 30 (8), 1513-1518, 2010 | 365 | 2010 |
Lack of the antioxidant enzyme glutathione peroxidase-1 accelerates atherosclerosis in diabetic apolipoprotein E–deficient mice P Lewis, N Stefanovic, J Pete, AC Calkin, S Giunti, V Thallas-Bonke, ... Circulation 115 (16), 2178-2187, 2007 | 268 | 2007 |
Reconstituted High-Density Lipoprotein Attenuates Platelet Function in Individuals With Type 2 Diabetes Mellitus by Promoting Cholesterol Efflux AC Calkin, BG Drew, A Ono, SJ Duffy, MV Gordon, SM Schoenwaelder, ... Circulation 120 (21), 2095-2104, 2009 | 252 | 2009 |
FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption BL Clifford, LR Sedgeman, KJ Williams, P Morand, A Cheng, KE Jarrett, ... Cell metabolism 33 (8), 1671-1684. e4, 2021 | 227 | 2021 |
Reactive oxygen species can provide atheroprotection via NOX4-dependent inhibition of inflammation and vascular remodeling SP Gray, E Di Marco, K Kennedy, P Chew, J Okabe, A El-Osta, AC Calkin, ... Arteriosclerosis, thrombosis, and vascular biology 36 (2), 295-307, 2016 | 190 | 2016 |
Rosiglitazone attenuates atherosclerosis in a model of insulin insufficiency independent of its metabolic effects AC Calkin, JM Forbes, CM Smith, M Lassila, ME Cooper, ... Arteriosclerosis, thrombosis, and vascular biology 25 (9), 1903-1909, 2005 | 179 | 2005 |
Accelerated nephropathy in diabetic apolipoprotein e-knockout mouse: role of advanced glycation end products M Lassila, KK Seah, TJ Allen, V Thallas, MC Thomas, R Candido, ... Journal of the American Society of Nephrology 15 (8), 2125-2138, 2004 | 162 | 2004 |
Imatinib attenuates diabetic nephropathy in apolipoprotein E-knockout mice M Lassila, K Jandeleit-Dahm, KK Seah, CM Smith, AC Calkin, TJ Allen, ... Journal of the American Society of Nephrology 16 (2), 363-373, 2005 | 143 | 2005 |
PPAR-α and-γ agonists attenuate diabetic kidney disease in the apolipoprotein E knockout mouse AC Calkin, S Giunti, KA Jandeleit-Dahm, TJ Allen, ME Cooper, ... Nephrology Dialysis Transplantation 21 (9), 2399-2405, 2006 | 133 | 2006 |
An integrative systems genetic analysis of mammalian lipid metabolism BL Parker, AC Calkin, MM Seldin, MF Keating, EJ Tarling, P Yang, ... Nature 567 (7747), 187-193, 2019 | 117 | 2019 |
Gemfibrozil decreases atherosclerosis in experimental diabetes in association with a reduction in oxidative stress and inflammation AC Calkin, ME Cooper, KA Jandeleit-Dahm, TJ Allen Diabetologia 49, 766-774, 2006 | 100 | 2006 |
The IDOL–UBE2D complex mediates sterol-dependent degradation of the LDL receptor L Zhang, L Fairall, BT Goult, AC Calkin, C Hong, CJ Millard, P Tontonoz, ... Genes & development 25 (12), 1262-1274, 2011 | 96 | 2011 |
Delayed intervention with AGE inhibitors attenuates the progression of diabetes-accelerated atherosclerosis in diabetic apolipoprotein E knockout mice AMD Watson, A Soro-Paavonen, K Sheehy, J Li, AC Calkin, A Koitka, ... Diabetologia 54, 681-689, 2011 | 87 | 2011 |
Estrogen receptor (ER) α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression BG Drew, H Hamidi, Z Zhou, CJ Villanueva, SA Krum, AC Calkin, ... Journal of Biological Chemistry 290 (9), 5566-5581, 2015 | 78 | 2015 |
The HMG-CoA reductase inhibitor rosuvastatin and the angiotensin receptor antagonist candesartan attenuate atherosclerosis in an apolipoprotein E-deficient mouse model of … AC Calkin, S Giunti, KJ Sheehy, C Chew, V Boolell, YS Rajaram, ... Diabetologia 51, 1731-1740, 2008 | 76 | 2008 |
Lipid metabolism and its implications for type 1 diabetes-associated cardiomyopathy RH Ritchie, EJ Zerenturk, D Prakoso, AC Calkin Journal of molecular endocrinology 58 (4), R225-R240, 2017 | 74 | 2017 |
FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors AC Calkin, BT Goult, L Zhang, L Fairall, C Hong, JWR Schwabe, ... Proceedings of the National Academy of Sciences 108 (50), 20107-20112, 2011 | 70 | 2011 |