| Biocatalytic reductions and chemical versatility of the old yellow enzyme family of flavoprotein oxidoreductases HS Toogood, JM Gardiner, NS Scrutton ChemCatChem 2 (8), 892-914, 2010 | 326 | 2010 |
| Discovery, characterization, engineering, and applications of ene-reductases for industrial biocatalysis HS Toogood, NS Scrutton ACS catalysis 8 (4), 3532-3549, 2018 | 228 | 2018 |
| New developments in ‘ene’-reductase catalysed biological hydrogenations HS Toogood, NS Scrutton Current opinion in chemical biology 19, 107-115, 2014 | 157 | 2014 |
| Calcium-mediated thermostability in the subtilisin superfamily: the crystal structure of Bacillus Ak. 1 protease at 1.8 Å resolution CA Smith, HS Toogood, HM Baker, RM Daniel, EN Baker Journal of molecular biology 294 (4), 1027-1040, 1999 | 145 | 1999 |
| Biocatalysis with thermostable enzymes: structure and properties of a thermophilic ‘ene’‐reductase related to old yellow enzyme BV Adalbjörnsson, HS Toogood, A Fryszkowska, CR Pudney, TA Jowitt, ... ChemBioChem 11 (2), 197-207, 2010 | 138 | 2010 |
| Asymmetric reduction of activated alkenes by pentaerythritol tetranitrate reductase: specificity and control of stereochemical outcome by reaction optimisation A Fryszkowska, H Toogood, M Sakuma, JM Gardiner, GM Stephens, ... Advanced synthesis & catalysis 351 (17), 2976-2990, 2009 | 137 | 2009 |
| Flavocytochrome P450 BM3: an update on structure and mechanism of a biotechnologically important enzyme AJ Warman, O Roitel, R Neeli, HM Girvan, HE Seward, SA Murray, ... Biochemical Society Transactions 33 (4), 747-753, 2005 | 134 | 2005 |
| Dynamics driving function− new insights from electron transferring flavoproteins and partner complexes HS Toogood, D Leys, NS Scrutton The FEBS journal 274 (21), 5481-5504, 2007 | 131 | 2007 |
| Structure‐based insight into the asymmetric bioreduction of the C C double bond of α, β‐unsaturated nitroalkenes by pentaerythritol tetranitrate reductase HS Toogood, A Fryszkowska, V Hare, K Fisher, A Roujeinikova, D Leys, ... Advanced synthesis & catalysis 350 (17), 2789-2803, 2008 | 103 | 2008 |
| Extensive domain motion and electron transfer in the human electron transferring flavoprotein· medium chain acyl-CoA dehydrogenase complex HS Toogood, A Van Thiel, J Basran, MJ Sutcliffe, NS Scrutton, D Leys Journal of Biological Chemistry 279 (31), 32904-32912, 2004 | 103 | 2004 |
| Machine Learning of Designed Translational Control Allows Predictive Pathway Optimization in Escherichia coli AJ Jervis, P Carbonell, M Vinaixa, MS Dunstan, KA Hollywood, ... ACS synthetic biology 8 (1), 127-136, 2018 | 93 | 2018 |
| Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets: new heme ligation states influence conformational equilibria in … HM Girvan, HE Seward, HS Toogood, MR Cheesman, D Leys, AW Munro Journal of Biological Chemistry 282 (1), 564-572, 2007 | 92 | 2007 |
| Low carbon strategies for sustainable bio-alkane gas production and renewable energy M Amer, EZ Wojcik, C Sun, R Hoeven, JMX Hughes, M Faulkner, ... Energy & Environmental Science 13 (6), 1818-1831, 2020 | 90 | 2020 |
| Cysteine activation is an inherent in vitro property of prolyl-tRNA synthetases I Ahel, C Stathopoulos, A Ambrogelly, A Sauerwald, H Toogood, ... Journal of Biological Chemistry 277 (38), 34743-34748, 2002 | 88 | 2002 |
| Enzymatic Menthol Production: One-Pot Approach Using Engineered Escherichia coli HS Toogood, AN Cheallaigh, S Tait, DJ Mansell, A Jervis, A Lygidakis, ... ACS Synthetic Biology 4 (10), 1112-1123, 2015 | 86 | 2015 |
| A site‐saturated mutagenesis study of pentaerythritol tetranitrate reductase reveals that residues 181 and 184 influence ligand binding, stereochemistry and reactivity HS Toogood, A Fryszkowska, M Hulley, M Sakuma, D Mansell, ... ChemBioChem 12 (5), 738-749, 2011 | 80 | 2011 |
| Focused directed evolution of pentaerythritol tetranitrate reductase by using automated anaerobic kinetic screening of site‐saturated libraries ME Hulley, HS Toogood, A Fryszkowska, D Mansell, GM Stephens, ... ChemBioChem 11 (17), 2433-2447, 2010 | 70 | 2010 |
| The use of a thermostable signature amidase in the resolution of the bicyclic synthon (rac)-γ-lactam HS Toogood, RC Brown, K Line, PA Keene, SJC Taylor, R McCague, ... Tetrahedron 60 (3), 711-716, 2004 | 69 | 2004 |
| Biocatalytic Asymmetric Alkene Reduction: Crystal Structure and Characterization of a Double Bond Reductase from Nicotiana tabacum DJ Mansell, HS Toogood, J Waller, JMX Hughes, CW Levy, JM Gardiner, ... ACS catalysis 3 (3), 370-379, 2013 | 68 | 2013 |
| Light-driven biocatalytic reduction of α, β-unsaturated compounds by ene reductases employing transition metal complexes as photosensitizers MK Peers, HS Toogood, DJ Heyes, D Mansell, BJ Coe, NS Scrutton Catalysis science & technology 6 (1), 169-177, 2016 | 57 | 2016 |
