| Receptor-tyrosine-kinase-and Gβγ-mediated MAP kinase activation by a common signalling pathway T Blesen, BE Hawes, DK Luttrell, KM Krueger, K Touhara, E Porfflri, ... Nature 376 (6543), 781-784, 1995 | 703 | 1995 |
| Role of c-Src tyrosine kinase in G protein-coupled receptorand Gβγ subunit-mediated activation of mitogen-activated protein kinases LM Luttrell, BE Hawes, T van Biesen, DK Luttrell, TJ Lansing, ... Journal of Biological Chemistry 271 (32), 19443-19450, 1996 | 677 | 1996 |
| Gβγ subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor: a scaffold for G protein-coupled receptor-mediated Ras activation LM Luttrell, GJ Della Rocca, T van Biesen, DK Luttrell, RJ Lefkowitz Journal of Biological Chemistry 272 (7), 4637-4644, 1997 | 595 | 1997 |
| Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors: convergence of Gi-and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase GJ Della Rocca, T van Biesen, Y Daaka, DK Luttrell, LM Luttrell, ... Journal of Biological Chemistry 272 (31), 19125-19132, 1997 | 564 | 1997 |
| A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat MF Jarvis, EC Burgard, S McGaraughty, P Honore, K Lynch, TJ Brennan, ... Proceedings of the National Academy of Sciences 99 (26), 17179-17184, 2002 | 558 | 2002 |
| Distinct Pathways of Gi-and Gq-mediated Mitogen-activated Protein Kinase Activation (∗) BE Hawes, T van Biesen, WJ Koch, LM Luttrell, RJ Lefkowitz Journal of Biological Chemistry 270 (29), 17148-17153, 1995 | 542 | 1995 |
| Mitogenic signaling via G protein-coupled receptors T van Biesen, LM Luttrell, BE Hawes, RJ Lefkowitz Endocrine reviews 17 (6), 698-714, 1996 | 533 | 1996 |
| Phosphatidylinositol 3-Kinase Is an Early Intermediate in the Gβγ-mediated Mitogen-activated Protein Kinase Signaling Pathway (∗) BE Hawes, LM Luttrell, T van Biesen, RJ Lefkowitz Journal of Biological Chemistry 271 (21), 12133-12136, 1996 | 443 | 1996 |
| Pharmacological characterization of recombinant human and rat P2X receptor subtypes BR Bianchi, KJ Lynch, E Touma, W Niforatos, EC Burgard, KM Alexander, ... European journal of pharmacology 376 (1-2), 127-138, 1999 | 402 | 1999 |
| Go-protein α-Subunits Activate Mitogen-activated Protein Kinase via a Novel Protein Kinase C-dependent Mechanism (∗) T van Biesen, BE Hawes, JR Raymond, LM Luttrell, WJ Koch, ... Journal of Biological Chemistry 271 (3), 1266-1269, 1996 | 271 | 1996 |
| Gβγ subunits mediate mitogen-activated protein kinase activation by the tyrosine kinase insulin-like growth factor 1 receptor LM Luttrell, T van Biesen, BE Hawes, WJ Koch, K Touhara, RJ Lefkowitz Journal of Biological Chemistry 270 (28), 16495-16498, 1995 | 252 | 1995 |
| Interaction of biofilm bacteria with antibiotics in a novel in vitro chemostat system H Anwar, T van Biesen, M Dasgupta, K Lam, JW Costerton Antimicrobial agents and chemotherapy 33 (10), 1824-1826, 1989 | 245 | 1989 |
| P2X receptor–mediated ionic currents in dorsal root ganglion neurons EC Burgard, W Niforatos, T van Biesen, KJ Lynch, E Touma, RE Metzger, ... Journal of Neurophysiology 82 (3), 1590-1598, 1999 | 186 | 1999 |
| G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein. K Touhara, BE Hawes, T van Biesen, RJ Lefkowitz Proceedings of the National Academy of Sciences 92 (20), 9284-9287, 1995 | 166 | 1995 |
| G-protein-coupled receptors and their regulation: activation of the MAP kinase signaling pathway by G-protein-coupled receptors. LM Luttrell, T van Biesen, BE Hawes, WJ Koch, KM Krueger, K Touhara, ... Advances in second messenger and phosphoprotein research 31, 263-277, 1997 | 144 | 1997 |
| Ras-Dependent Activation of Fibroblast Mitogen-Activated Protein Kinase by 5-HT1A Receptor via a G Protein βγ-Subunit-Initiated Pathway MN Garnovskaya, T van Biesen, B Hawes, S Casañas Ramos, ... Biochemistry 35 (43), 13716-13722, 1996 | 133 | 1996 |
| Modulation of BzATP and formalin induced nociception: attenuation by the P2X receptor antagonist, TNP‐ATP and enhancement by the P2X3 allosteric modulator … MF Jarvis, CT Wismer, E Schweitzer, H Yu, T Van Biesen, KJ Lynch, ... British journal of pharmacology 132 (1), 259-269, 2001 | 126 | 2001 |
| Activation of Ras and mitogen-activated protein kinase pathway by terminal complement complexes is G protein dependent. F Niculescu, H Rus, T Van Biesen, ML Shin Journal of immunology (Baltimore, Md.: 1950) 158 (9), 4405-4412, 1997 | 126 | 1997 |
| Molecular and functional characterization of human P2X2 receptors KJ Lynch, E Touma, W Niforatos, KL Kage, EC Burgard, T van Biesen, ... Molecular pharmacology 56 (6), 1171-1181, 1999 | 125 | 1999 |
| Degradation of FinP antisense RNA from F-like plasmids: the RNA-binding protein, FinO, protects FinP from ribonuclease E LJ Jerome, T van Biesen, LS Frost Journal of molecular biology 285 (4), 1457-1473, 1999 | 102 | 1999 |
Robert J. LefkowitzJames B. Duke Professor of Medicine, Biochemistry, Chemistry; HHMI, Duke University在 receptor-biol.duke.edu 的电子邮件经过验证
Robert J. LefkowitzJames B. Duke Professor of Medicine, Biochemistry, Chemistry; HHMI, Duke University在 receptor-biol.duke.edu 的电子邮件经过验证