Single-cell transcriptomics of regulatory T cells reveals trajectories of tissue adaptation RJ Miragaia, T Gomes, A Chomka, L Jardine, A Riedel, AN Hegazy, ... Immunity 50 (2), 493-504. e7, 2019 | 451 | 2019 |
Single-cell RNA sequencing reveals a dynamic stromal niche that supports tumor growth S Davidson, M Efremova, A Riedel, B Mahata, J Pramanik, J Huuhtanen, ... Cell reports 31 (7), 2020 | 225 | 2020 |
Tumor-induced stromal reprogramming drives lymph node transformation A Riedel, D Shorthouse, L Haas, BA Hall, J Shields Nature immunology 17 (9), 1118-1127, 2016 | 164 | 2016 |
ILC2-driven innate immune checkpoint mechanism antagonizes NK cell antimetastatic function in the lung MJ Schuijs, S Png, AC Richard, A Tsyben, G Hamm, J Stockis, C Garcia, ... Nature immunology 21 (9), 998-1009, 2020 | 142 | 2020 |
Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs M Pein, J Insua-Rodríguez, T Hongu, A Riedel, J Meier, L Wiedmann, ... Nature communications 11 (1), 1494, 2020 | 137 | 2020 |
Tumors induce de novo steroid biosynthesis in T cells to evade immunity B Mahata, J Pramanik, L van der Weyden, K Polanski, G Kar, A Riedel, ... Nature communications 11 (1), 3588, 2020 | 71 | 2020 |
Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs T Hongu, M Pein, J Insua-Rodriguez, E Gutjahr, G Mattavelli, J Meier, ... Nature cancer 3 (4), 486-504, 2022 | 62 | 2022 |
Single-and double-hit events in genes encoding immune targets before and after T cell–engaging antibody therapy in MM MS Truger, J Duell, X Zhou, L Heimeshoff, A Ruckdeschel, M John, ... Blood advances 5 (19), 3794-3798, 2021 | 44 | 2021 |
ECM1 secreted by HER2-overexpressing breast cancer cells promotes formation of a vascular niche accelerating cancer cell migration and invasion SS Steinhaeuser, E Morera, Z Budkova, A Schepsky, Q Wang, O Rolfsson, ... Laboratory Investigation 100 (7), 928-944, 2020 | 42 | 2020 |
CFP suppresses breast cancer cell growth by TES-mediated upregulation of the transcription factor DDIT3 I Block, C Müller, D Sdogati, H Pedersen, M List, AM Jaskot, SD Syse, ... Oncogene 38 (23), 4560-4573, 2019 | 30 | 2019 |
Identification of a DMBT1 polymorphism associated with increased breast cancer risk and decreased promoter activity S Tchatchou, A Riedel, S Lyer, J Schmutzhard, O Strobel‐Freidekind, ... Human mutation 31 (1), 60-66, 2010 | 24 | 2010 |
Exploring the role of stromal osmoregulation in cancer and disease using executable modelling D Shorthouse, A Riedel, E Kerr, L Pedro, D Bihary, S Samarajiwa, ... Nature Communications 9 (1), 3011, 2018 | 23 | 2018 |
Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment M Haake, B Haack, T Schäfer, PN Harter, G Mattavelli, P Eiring, N Vashist, ... Nature Communications 14 (1), 4253, 2023 | 18 | 2023 |
Single-cell RNA sequencing reveals a dynamic stromal niche within the evolving tumour microenvironment S Davidson, M Efremova, A Riedel, B Mahata, J Pramanik, J Huuhtanen, ... bioRxiv, 467225, 2018 | 16 | 2018 |
Tumor-derived lactic acid modulates activation and metabolic status of draining lymph node stroma A Riedel, M Helal, L Pedro, JJ Swietlik, D Shorthouse, W Schmitz, L Haas, ... Cancer immunology research 10 (4), 482-497, 2022 | 14 | 2022 |
CD52 and OXPHOS—potential targets in ibrutinib-treated mantle cell lymphoma V Fuhr, S Heidenreich, M Srivastava, A Riedel, J Düll, ... Cell Death Discovery 8 (1), 505, 2022 | 7 | 2022 |
Time-resolved scRNA-seq tracks the adaptation of a sensitive MCL cell line to ibrutinib treatment V Fuhr, E Vafadarnejad, O Dietrich, P Arampatzi, A Riedel, AE Saliba, ... International Journal of Molecular Sciences 22 (5), 2276, 2021 | 6 | 2021 |
Fibroblastic reticular cells mitigate acute GvHD via MHCII-dependent maintenance of regulatory T cells H Shaikh, J Pezoldt, Z Mokhtari, JG Vargas, DD Le, JP Mosca, EA Viera, ... JCI insight 7 (22), 2022 | 4 | 2022 |
PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma A Gaballa, A Gebhardt-Wolf, B Krenz, G Mattavelli, M John, G Cossa, ... Nature Communications 15 (1), 1446, 2024 | 2 | 2024 |
High-dose carfilzomib achieves superior anti-tumor activity over low-dose and recaptures response in relapsed/refractory multiple myeloma resistant to low-dose carfilzomib by … X Zhou, A Besse, J Peter, MJ Steinhardt, C Vogt, S Nerreter, E Teufel, ... Haematologica 108 (6), 1628, 2023 | 2 | 2023 |