X-ray structure of a tetranucleosome and its implications for the chromatin fibre T Schalch, S Duda, DF Sargent, TJ Richmond Nature 436 (7047), 138-141, 2005 | 1035 | 2005 |
Nucleosome arrays reveal the two-start organization of the chromatin fiber B Dorigo, T Schalch, A Kulangara, S Duda, RR Schroeder, TJ Richmond Science 306 (5701), 1571-1573, 2004 | 738 | 2004 |
Chromatin fiber folding: requirement for the histone H4 N-terminal tail B Dorigo, T Schalch, K Bystricky, TJ Richmond Journal of molecular biology 327 (1), 85-96, 2003 | 678 | 2003 |
The molecular architecture of the metalloprotease FtsH C Bieniossek, T Schalch, M Bumann, M Meister, R Meier, U Baumann Proceedings of the National Academy of Sciences 103 (9), 3066-3071, 2006 | 192 | 2006 |
High-affinity binding of Chp1 chromodomain to K9 methylated histone H3 is required to establish centromeric heterochromatin T Schalch, G Job, VJ Noffsinger, S Shanker, C Kuscu, L Joshua-Tor, ... Molecular cell 34 (1), 36-46, 2009 | 135 | 2009 |
Capturing structural heterogeneity in chromatin fibers B Ekundayo, TJ Richmond, T Schalch Journal of molecular biology 429 (20), 3031-3042, 2017 | 67 | 2017 |
Structure of centromere chromatin: from nucleosome to chromosomal architecture T Schalch, FA Steiner Chromosoma 126, 443-455, 2017 | 67 | 2017 |
Chd5 requires PHD-mediated histone 3 binding for tumor suppression S Paul, A Kuo, T Schalch, H Vogel, L Joshua-Tor, WR McCombie, ... Cell reports 3 (1), 92-102, 2013 | 58 | 2013 |
The Chp1–Tas3 core is a multifunctional platform critical for gene silencing by RITS T Schalch, G Job, S Shanker, JF Partridge, L Joshua-Tor Nature structural & molecular biology 18 (12), 1351-1357, 2011 | 55 | 2011 |
SHREC silences heterochromatin via distinct remodeling and deacetylation modules G Job, C Brugger, T Xu, BR Lowe, Y Pfister, C Qu, S Shanker, JIB Sanz, ... Molecular cell 62 (2), 207-221, 2016 | 53 | 2016 |
Revisiting chromatin binding of the Arabidopsis UV-B photoreceptor UVR8 M Binkert, CD Crocco, B Ekundayo, K Lau, S Raffelberg, K Tilbrook, R Yin, ... BMC plant biology 16, 1-11, 2016 | 41 | 2016 |
CRL4-like Clr4 complex in Schizosaccharomyces pombe depends on an exposed surface of Dos1 for heterochromatin silencing C Kuscu, M Zaratiegui, HS Kim, DA Wah, RA Martienssen, T Schalch, ... Proceedings of the National Academy of Sciences 111 (5), 1795-1800, 2014 | 28 | 2014 |
Structural insights into p300 regulation and acetylation-dependent genome organisation Z Ibrahim, T Wang, O Destaing, N Salvi, N Hoghoughi, C Chabert, A Rusu, ... Nature communications 13 (1), 7759, 2022 | 26 | 2022 |
Transcriptional gene silencing requires dedicated interaction between HP1 protein Chp2 and chromatin remodeler Mit1 K Leopold, A Stirpe, T Schalch Genes & development 33 (9-10), 565-577, 2019 | 22 | 2019 |
SUV39 SET domains mediate crosstalk of heterochromatic histone marks A Stirpe, N Guidotti, SJ Northall, S Kilic, A Hainard, O Vadas, B Fierz, ... Elife 10, e62682, 2021 | 21 | 2021 |
Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia M Grimaldi, M Karaca, L Latini, E Brioudes, T Schalch, P Maechler Human molecular genetics 26 (18), 3453-3465, 2017 | 21 | 2017 |
Chromatin fiber structural motifs as regulatory hubs of genome function? M Moraru, T Schalch Essays in biochemistry 63 (1), 123-132, 2019 | 15 | 2019 |
The histone H3K9M mutation synergizes with H3K14 ubiquitylation to selectively sequester histone H3K9 methyltransferase Clr4 at heterochromatin CM Shan, JK Kim, J Wang, K Bao, Y Sun, H Chen, JX Yue, A Stirpe, ... Cell reports 35 (7), 2021 | 9 | 2021 |
The 30-nm chromatin fiber: in vitro reconstitution and structural analysis T Schalch Diss., Naturwissenschaften, Eidgenössische Technische Hochschule ETH Zürich …, 2004 | 8 | 2004 |
Panspecies small-molecule disruptors of heterochromatin-mediated transcriptional gene silencing E Castonguay, SA White, A Kagansky, DJ St-Cyr, AG Castillo, C Brugger, ... Molecular and cellular biology 35 (4), 662-674, 2015 | 6 | 2015 |