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Nicole Wyttenbach
Nicole Wyttenbach
Scientist
在 roche.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Glass-forming ability of compounds in marketed amorphous drug products
N Wyttenbach, M Kuentz
European Journal of Pharmaceutics and Biopharmaceutics 112, 204-208, 2017
1162017
Compositions and uses thereof
D Desai, R Diodone, Z Go, PN Ibrahim, R Iyer, HJ Mair, HK Sandhu, ...
US Patent 9,447,089, 2016
802016
Miniaturized screening of polymers for amorphous drug stabilization (SPADS): rapid assessment of solid dispersion systems
N Wyttenbach, C Janas, M Siam, ME Lauer, L Jacob, E Scheubel, S Page
European Journal of Pharmaceutics and Biopharmaceutics 84 (3), 583-598, 2013
762013
Miniaturized assay for solubility and residual solid screening (SORESOS) in early drug development
N Wyttenbach, J Alsenz, O Grassmann
Pharmaceutical research 24, 888-898, 2007
712007
Drug-excipient compatibility testing using a high-throughput approach and statistical design
N Wyttenbach, C Birringer, J Alsenz, M Kuentz
Pharmaceutical development and technology 10 (4), 499-505, 2005
512005
A systematic study of molecular interactions of anionic drugs with a dimethylaminoethyl methacrylate copolymer regarding solubility enhancement
W Saal, A Ross, N Wyttenbach, J Alsenz, M Kuentz
Molecular pharmaceutics 14 (4), 1243-1250, 2017
492017
Theoretical considerations of the prigogine–defay ratio with regard to the glass-forming ability of drugs from undercooled melts
N Wyttenbach, W Kirchmeyer, J Alsenz, M Kuentz
Molecular pharmaceutics 13 (1), 241-250, 2016
432016
New prediction methods for solubility parameters based on molecular sigma profiles using pharmaceutical materials
A Niederquell, N Wyttenbach, M Kuentz
International journal of pharmaceutics 546 (1-2), 137-144, 2018
422018
Compositions and uses thereof
D Desai, R Diodone, Z Go, PN Ibrahim, R Iyer, HJ Mair, HK Sandhu, ...
US Patent 9,663,517, 2017
392017
Structured development approach for amorphous systems
N Shah, H Sandhu, DS Choi, O Kalb, S Page, N Wyttenbach
Formulating poorly water soluble drugs, 267-310, 2012
382012
Unexpected solubility enhancement of drug bases in the presence of a dimethylaminoethyl methacrylate copolymer
W Saal, A Ross, N Wyttenbach, J Alsenz, M Kuentz
Molecular pharmaceutics 15 (1), 186-192, 2018
282018
Influence of excipients on solvent-mediated hydrate formation of piroxicam studied by dynamic imaging and fractal analysis
W Kirchmeyer, N Wyttenbach, J Alsenz, M Kuentz
Crystal Growth & Design 15 (10), 5002-5010, 2015
252015
Formulating poorly water soluble drugs
N Shah, H Sandhu, DS Choi, O Kalb, S Page, N Wyttenbach
Springer: New York, NY, USA, 2012
222012
Machine estimation of drug melting properties and influence on solubility prediction
N Wyttenbach, A Niederquell, M Kuentz
Molecular pharmaceutics 17 (7), 2660-2671, 2020
212020
Compositions and uses thereof
D Desai, R Diodone, Z Go, PN Ibrahim, R Iyer, HJ Mair, HK Sandhu, ...
US Patent App. 15/606,682, 2018
212018
Application of a statistical method to the absorption of a new model drug from micellar and lipid formulations—evaluation of qualitative excipient effects
M Kuentz, N Wyttenbach, O Kuhlmann
Pharmaceutical development and technology 12 (3), 275-283, 2007
162007
Interactions of dimethylaminoethyl methacrylate copolymer with non-acidic drugs demonstrated high solubilization in vitro and pronounced sustained release in vivo
W Saal, N Wyttenbach, J Alsenz, M Kuentz
European Journal of Pharmaceutics and Biopharmaceutics 125, 68-75, 2018
152018
Miniaturized X-ray powder diffraction assay (MixRay) for quantitative kinetic analysis of solvent-mediated phase transformations in pharmaceutics
W Kirchmeyer, O Grassmann, N Wyttenbach, J Alsenz, M Kuentz
Journal of pharmaceutical and biomedical analysis 131, 195-201, 2016
142016
High-performance liquid chromatography of polyethylene glycols as their α, ω-bis (1-naphthylurethane) derivatives and signal monitoring by fluorescence detection
K Rissler, N Wyttenbach, KO Börnsen
Journal of Chromatography A 822 (2), 189-206, 1998
141998
Partial solvation parameters of drugs as a new thermodynamic tool for pharmaceutics
A Niederquell, N Wyttenbach, M Kuentz, C Panayiotou
Pharmaceutics 11 (1), 17, 2019
122019
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