| Phosphorylation-deficient G-protein-biased μ-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects A Kliewer, F Schmiedel, S Sianati, A Bailey, JT Bateman, ES Levitt, ... Nature communications 10 (1), 367, 2019 | 301 | 2019 |
| μ opioid receptor activation hyperpolarizes respiratory‐controlling Kölliker–Fuse neurons and suppresses post‐inspiratory drive ES Levitt, AP Abdala, JFR Paton, JM Bissonnette, JT Williams The Journal of physiology 593 (19), 4453-4469, 2015 | 131 | 2015 |
| Differential impact of two critical respiratory centres in opioid‐induced respiratory depression in awake mice AG Varga, BT Reid, BL Kieffer, ES Levitt The Journal of physiology 598 (1), 189-205, 2020 | 114 | 2020 |
| Differential effect of membrane cholesterol removal on mu and delta opioid receptors: A parallel comparison of acute and chronic signaling to adenylyl cyclase ES Levitt, MJ Clark, PM Jenkins, JR Martens, JR Traynor J Biol Chem 284, 22108-22, 2009 | 81 | 2009 |
| Neuronal mechanisms underlying opioid-induced respiratory depression: our current understanding JM Ramirez, NJ Burgraff, AD Wei, NA Baertsch, AG Varga, ... Journal of neurophysiology, 2021 | 75 | 2021 |
| Understanding and countering opioid‐induced respiratory depression JT Bateman, SE Saunders, ES Levitt British journal of pharmacology 180 (7), 813-828, 2023 | 65 | 2023 |
| Morphine desensitization and cellular tolerance are distinguished in rat locus coeruleus neurons ES Levitt, JT Williams Mol Pharmacol 82, 983-92, 2012 | 63 | 2012 |
| Gi/o-coupled receptors compete for signaling to adenylyl cyclase in SH-SY5Y cells and reduce opioid withdrawal-mediated cAMP overshoot ES Levitt, LC Purington, JR Traynor Mol Pharmacol 79 (3), 461-71, 2011 | 59 | 2011 |
| A selective 5-HT1A receptor agonist improves respiration in a mouse model of Rett syndrome ES Levitt, BJ Hunnicutt, SJ Knopp, JT Williams, JM Bissonnette J Appl Physiol 115, 1626-33, 2013 | 56 | 2013 |
| Kölliker-Fuse/Parabrachial complex mu opioid receptors contribute to fentanyl-induced apnea and respiratory rate depression SE Saunders, ES Levitt Respiratory Physiology & Neurobiology 275, 103388, 2020 | 52 | 2020 |
| Depression of serotonin synaptic transmission by the dopamine precursor L-DOPA SC Gantz, ES Levitt, N Llamosas, KA Neve, JT Williams Cell reports 12 (6), 944-954, 2015 | 42 | 2015 |
| Neurochemistry of the Kölliker‐Fuse nucleus from a respiratory perspective AG Varga, SN Maletz, JT Bateman, BT Reid, ES Levitt Journal of Neurochemistry 156 (1), 16-37, 2021 | 40 | 2021 |
| Desensitization and tolerance of mu opioid receptors on pontine Kölliker-Fuse neurons ES Levitt, JT Williams Molecular pharmacology 93 (1), 8-13, 2018 | 29 | 2018 |
| Design of high affinity cyclic pentapeptide ligands for kappa-opioid receptors MJ Przydzial, ID Pogozheva, JC Ho, KE Bosse, E Sawyer, JR Traynor, ... J Pept Res 66, 255-262, 2005 | 24 | 2005 |
| Evaluation of G protein bias and β-arrestin 2 signaling in opioid-induced respiratory depression JT Bateman, ES Levitt American Journal of Physiology-Cell Physiology 321 (4), C681-C683, 2021 | 15 | 2021 |
| Fentanyl effects on respiratory neuron activity in the dorsolateral pons SE Saunders, DM Baekey, ES Levitt Journal of Neurophysiology 128 (5), 1117-1132, 2022 | 14 | 2022 |
| Opioid suppression of an excitatory pontomedullary respiratory circuit by convergent mechanisms JT Bateman, ES Levitt Elife 12, e81119, 2023 | 12 | 2023 |
| Nucleus tractus solitarius neurons activated by hypercapnia and hypoxia lack mu opioid receptor expression SN Maletz, BT Reid, AG Varga, ES Levitt Frontiers in Molecular Neuroscience 15, 932189, 2022 | 9 | 2022 |
| Acute morphine blocks spinal respiratory motor plasticity via long‐latency mechanisms that require toll‐like receptor 4 signalling A Tadjalli, YB Seven, A Sharma, CR McCurdy, DC Bolser, ES Levitt, ... The Journal of physiology 599 (15), 3771-3797, 2021 | 5 | 2021 |
| Activation of orexin-2 receptors in the Kӧlliker-Fuse nucleus of anesthetized mice leads to transient slowing of respiratory rate AG Varga, JR Whitaker-Fornek, SN Maletz, ES Levitt Frontiers in Physiology 13, 977569, 2022 | 4 | 2022 |
