| Antisense oligonucleotides: modifications and clinical trials VK Sharma, RK Sharma, SK Singh MedChemComm 5 (10), 1454-1471, 2014 | 234 | 2014 |
| Synthesis, utility and medicinal importance of 1, 2-& 1, 4-dihydropyridines VK Sharma, SK Singh RSC advances 7 (5), 2682-2732, 2017 | 157 | 2017 |
| Oligonucleotide therapeutics: chemistry, delivery and clinical progress VK Sharma, JK Watts Future medicinal chemistry 7 (16), 2221-2242, 2015 | 114 | 2015 |
| Nucleic acid therapeutics: basic concepts and recent developments VK Sharma, P Rungta, AK Prasad RSC Advances 4 (32), 16618-16631, 2014 | 93 | 2014 |
| Oligonucleotides targeting TCF4 triplet repeat expansion inhibit RNA foci and mis-splicing in Fuchs’ dystrophy J Hu, Z Rong, X Gong, Z Zhou, VK Sharma, C Xing, JK Watts, DR Corey, ... Human molecular genetics 27 (6), 1015-1026, 2018 | 67 | 2018 |
| Novel cluster and monomer-based GalNAc structures induce effective uptake of siRNAs in vitro and in vivo VK Sharma, MF Osborn, MR Hassler, D Echeverria, S Ly, EA Ulashchik, ... Bioconjugate chemistry 29 (7), 2478-2488, 2018 | 38 | 2018 |
| Synthesis and biological properties of triazole-linked locked nucleic acid VK Sharma, SK Singh, PM Krishnamurthy, JF Alterman, RA Haraszti, ... Chemical Communications 53 (63), 8906-8909, 2017 | 37 | 2017 |
| Activation of frataxin protein expression by antisense oligonucleotides targeting the mutant expanded repeat L Li, X Shen, Z Liu, M Norrbom, TP Prakash, D O'Reilly, VK Sharma, ... nucleic acid therapeutics 28 (1), 23-33, 2018 | 36 | 2018 |
| Chemoenzymatic Convergent Synthesis of 2′-O,4′-C-Methyleneribonucleosides VK Sharma, M Kumar, CE Olsen, AK Prasad The Journal of organic chemistry 79 (13), 6336-6341, 2014 | 29 | 2014 |
| Locked nucleic acid gapmers and conjugates potently silence ADAM33, an asthma-associated metalloprotease with nuclear-localized mRNA HM Pendergraff, PM Krishnamurthy, AJ Debacker, MP Moazami, ... Molecular Therapy-Nucleic Acids 8, 158-168, 2017 | 24 | 2017 |
| Biocatalytic Deacylation Studies on Tetra-O-acyl-β-d-xylofuranosyl Nucleosides: Synthesis of xylo-LNA Monomers SK Singh, VK Sharma, K Bohra, CE Olsen, AK Prasad The Journal of Organic Chemistry 76 (18), 7556-7562, 2011 | 20 | 2011 |
| Chemoenzymatic Synthesis of C-4′-Spiro-oxetanoribonucleosides VK Sharma, M Kumar, D Sharma, CE Olsen, AK Prasad The Journal of Organic Chemistry 79 (18), 8516-8521, 2014 | 17 | 2014 |
| Reactions of 1,2- & 1,4-dihydropyridines SK Singh, VK Sharma Curr Org Chem 18 (9), 1159-1207, 2014 | 17 | 2014 |
| Biocatalytic Separation of N-7/N-9 Guanine Nucleosides SK Singh, VK Sharma, CE Olsen, J Wengel, VS Parmar, AK Prasad The Journal of Organic Chemistry 75 (22), 7932-7935, 2010 | 15 | 2010 |
| Design and synthesis of LNA-based mercaptoacetamido-linked nucleoside dimers VK Sharma, SK Singh, K Bohra, V Khatri, CE Olsen, AK Prasad Nucleosides, Nucleotides and Nucleic Acids 32 (5), 256-272, 2013 | 14 | 2013 |
| Next-Generation Peptide Nucleic Acid Chimeras Exhibit High Affinity and Potent Gene Silencing AJ Debacker, VK Sharma, P Meda Krishnamurthy, D O’Reilly, R Greenhill, ... Biochemistry 58 (6), 582-589, 2019 | 12 | 2019 |
| Chemo-enzymatic synthesis of bicyclic 3′-azido-and 3′-amino-nucleosides M Kumar, VK Sharma, CE Olsen, AK Prasad RSC Advances 4 (70), 37231-37235, 2014 | 12 | 2014 |
| Synthesis of triazole-linked LNA-based non-ionic nucleoside dimers using Cu(I)-catalyzed ‘Click’ reaction SK Singh, VK Sharma, K Bohra, CE Olsen, AK Prasad Curr. Org. Synth. 11 (5), 757-766, 2014 | 8 | 2014 |
| Biocatalytic route to C-3′-azido/-hydroxy-C-4′-spiro-oxetanoribonucleosides M Kumar, VK Sharma, R Kumar, AK Prasad Carbohydrate research 417, 19-26, 2015 | 7 | 2015 |
| Design and Synthesis of Triazole-Linked xylo-Nucleoside Dimers S Srivastava, SK Singh, VK Sharma, P Mangla, CE Olsen, AK Prasad Nucleosides, Nucleotides and Nucleic Acids 34 (6), 388-399, 2015 | 7 | 2015 |
Jonathan K. WattsProfessor, RNA Therapeutics Institute, UMass Chan Medical School在 umassmed.edu 的电子邮件经过验证
Jonathan K. WattsProfessor, RNA Therapeutics Institute, UMass Chan Medical School在 umassmed.edu 的电子邮件经过验证
Pranathi Meda KrishnamurthyBristol Myers Squibb在 umassmed.edu 的电子邮件经过验证