Inflammation and joint destruction may be linked to the generation of cartilage metabolites of ADAMTS-5 through activation of toll-like receptors N Sharma, P Drobinski, A Kayed, Z Chen, CF Kjelgaard-Petersen, ... Osteoarthritis and Cartilage 28 (5), 658-668, 2020 | 36 | 2020 |
The prototypical proton-coupled oligopeptide transporter YdgR from Escherichia coli facilitates chloramphenicol uptake into bacterial cells BK Prabhala, NG Aduri, N Sharma, A Shaheen, A Sharma, M Iqbal, ... Journal of Biological Chemistry 293 (3), 1007-1017, 2018 | 25 | 2018 |
Tofacitinib and TPCA-1 exert chondroprotective effects on extracellular matrix turnover in bovine articular cartilage ex vivo CF Kjelgaard-Petersen, N Sharma, A Kayed, MA Karsdal, A Mobasheri, ... Biochemical pharmacology 165, 91-98, 2019 | 19 | 2019 |
Peptide selectivity of the proton-coupled oligopeptide transporter from Neisseria meningitidis N Sharma, NG Aduri, A Iqbal, BK Prabhala, O Mirza Journal of Molecular Microbiology and Biotechnology 26 (5), 312-319, 2016 | 10 | 2016 |
Blood and urinary collagen markers in osteoarthritis: markers of tissue turnover and disease activity AC Bay-Jensen, A Engstroem, N Sharma, MA Karsdal Expert Review of Molecular Diagnostics 20 (1), 57-68, 2020 | 7 | 2020 |
Functional Heterogeneity Within Osteoclast Populations—a Critical Review of Four Key Publications that May Change the Paradigm of Osteoclasts N Sharma, MM Weivoda, K Søe Current osteoporosis reports 20 (5), 344-355, 2022 | 2 | 2022 |
ADAMTS-5 degraded cartilage increases tissue turnover in synovial membrane explants and stimulation is inhibited by the anti ADAMTS-5 nanobody, M6495 N Sharma, AC Bay-Jensen, HS Hector, T Gantzel, M Michaelis, C Ladel, ... Osteoarthritis and Cartilage 28, S118-S119, 2020 | 1 | 2020 |
The anti-ADAMTS-5 nanobody®, M6495, inhibits the activation of TLR by ADAMTS-5-mediated degradation fragments in cartilage explants N Sharma, P Drobinski, M Karsdal, AC Bay-Jensen, C Thudium, ... Osteoarthritis and Cartilage 27, S89, 2019 | 1 | 2019 |
A perspective on muscle phenotyping in musculoskeletal research I Foessl, CL Ackert-Bicknell, E Kague, F Laskou, F Jakob, D Karasik, ... Trends in Endocrinology & Metabolism, 2024 | | 2024 |
Human osteoclasts in vitro are dose dependently both inhibited and stimulated by cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) SSR Nielsen, JAZ Pedersen, N Sharma, PK Wasehuus, MS Hansen, ... Bone, 117035, 2024 | | 2024 |
Functional Characterization of the Putative POT from Clostridium perfringens H Gharabli, M Rafiq, A Iqbal, R Yan, NG Aduri, N Sharma, BK Prabhala, ... Biology 12 (5), 651, 2023 | | 2023 |
Human osteoclasts in vitro are both inhibited and stimulated dose dependently by cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) SSR Nielsen, JAZ Pedersen, N Sharma, PK Wasehuus, AMJ Møller, ... Bone Reports 16 (Suppl.), 40-41, 2022 | | 2022 |
Biomarker of type I collagen remodeling C1M is associated with erosive hand osteoarthritis in a hospital-based observational cohort-the nor-hand study CS Thudium, N Sharma, P Frederiksen, AC Bay-Jensen, IK Haugen Osteoarthritis and Cartilage 28, S322, 2020 | | 2020 |
AB0047 ACTIVATION OF TLR2 BY ADAMTS-5-MEDIATED DEGRADATION FRAGMENTS OF CARTILAGE EXPLANTS IS INHIBITED BY THE ANTI-ADAMTS-5 NANOBODY®, M6495 N Sharma, C Thudium, M Karsdal, AC Bay-Jensen, T Gantzel, ... Annals of the Rheumatic Diseases 78 (Suppl 2), 1489-1489, 2019 | | 2019 |
SAT0013 Il-1Α and adamts5 mediated tissue damage in human cartilage explants leads to generation of tlr2 activating damps N Sharma, TG Christiansen, M Karsdal, AC Bay-Jensen, CS Thudium Annals of the Rheumatic Diseases 77 (Suppl 2), 875-875, 2018 | | 2018 |
Ex vivo inhibition of JAK and IKK preserves cartilage formation in catabolically stimulated bovine articular cartilage CS Thudium, CF Kjelgaard-Petersen, N Sharma, A Mobasheri, ... Osteoarthritis and Cartilage 26, S132, 2018 | | 2018 |
Modulation of Cartilage Degradation Biomarkers Reflect the Activation and Inhibition of Pro-Inflammatory Cytokine Signaling in an Ex Vivo Model of Bovine Cartilage CF Kjelgaard-Petersen, N Sharma, A Kayed, B Christensen, M Karsdal, ... Arthritis and Rheumatology 69 (Suppl. 10), 969, 2017 | | 2017 |
Activation of Toll-like Receptor 2 in Human Synovium Explants Increase Tissue Turnover and Secretion of Interleukin-6 N Sharma, A Kayed, CF Kjelgaard-Petersen, TG Christiansen, M Karsdal, ... Arthritis and Rheumatology 69, 1063, 2017 | | 2017 |