Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist HE Broxmeyer, CM Orschell, DW Clapp, G Hangoc, S Cooper, PA Plett, ... The Journal of experimental medicine 201 (8), 1307-1318, 2005 | 1380 | 2005 |
Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells G Bollag, DW Clapp, S Shih, F Adler, YY Zhang, P Thompson, BJ Lange, ... Nature genetics 12 (2), 144-148, 1996 | 693 | 1996 |
Selumetinib in children with inoperable plexiform neurofibromas AM Gross, PL Wolters, E Dombi, A Baldwin, P Whitcomb, MJ Fisher, ... New England Journal of Medicine 382 (15), 1430-1442, 2020 | 511 | 2020 |
Nf1-dependent tumors require a microenvironment containing Nf1+/−-and c-kit-dependent bone marrow FC Yang, DA Ingram, S Chen, Y Zhu, J Yuan, X Li, X Yang, S Knowles, ... Cell 135 (3), 437-448, 2008 | 397 | 2008 |
Fanconi anaemia and cancer: an intricate relationship G Nalepa, DW Clapp Nature Reviews Cancer 18 (3), 168-185, 2018 | 377 | 2018 |
Cell Cycle-Related Changes in Repopulating Capacity of Human Mobilized Peripheral Blood CD34+ Cells in Non-Obese Diabetic/Severe Combined Immune … A Gothot, JCM Van der Loo, DW Clapp, EF Srour Blood, The Journal of the American Society of Hematology 92 (8), 2641-2649, 1998 | 373 | 1998 |
Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial KA Robertson, G Nalepa, FC Yang, DC Bowers, CY Ho, GD Hutchins, ... The lancet oncology 13 (12), 1218-1224, 2012 | 253 | 2012 |
Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/– mast cells Y Feng-Chun, DA Ingram, S Chen, CM Hingtgen, N Ratner, KR Monk, ... The Journal of clinical investigation 112 (12), 1851-1861, 2003 | 252 | 2003 |
Stromal cell-derived factor-1/CXCL12 directly enhances survival/antiapoptosis of myeloid progenitor cells through CXCR4 and Gαi proteins and enhances engraftment of competitive … HE Broxmeyer, L Kohli, CH Kim, Y Lee, C Mantel, S Cooper, G Hangoc, ... Journal of Leucocyte Biology 73 (5), 630-638, 2003 | 245 | 2003 |
Fanconi anemia proteins function in mitophagy and immunity R Sumpter, S Sirasanagandla, ÁF Fernández, Y Wei, X Dong, L Franco, ... Cell 165 (4), 867-881, 2016 | 234 | 2016 |
LacZ and Interleukin-3 Expression In Vivo after Retroviral Transduction of Marrow-Derived Human Osteogenic Mesenchymal Progenitors JA Allay, JE Dennis, SE Haynesworth, MK Majumdar, DW Clapp, ... Human gene therapy 8 (12), 1417-1427, 1997 | 228 | 1997 |
Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo DA Ingram, FC Yang, JB Travers, MJ Wenning, K Hiatt, S New, A Hood, ... The Journal of experimental medicine 191 (1), 181-188, 2000 | 219 | 2000 |
Multiple Inhibitory Cytokines Induce Deregulated Progenitor Growth and Apoptosis in Hematopoietic Cells From Fac−/− Mice LS Haneline, HE Broxmeyer, S Cooper, G Hangoc, M Carreau, ... Blood, The Journal of the American Society of Hematology 91 (11), 4092-4098, 1998 | 214 | 1998 |
High efficiency retroviral mediated gene transduction into single isolated immature and replatable CD34 (3+) hematopoietic stem/progenitor cells from human umbilical cord blood. L Lu, M Xiao, DW Clapp, ZH Li, HE Broxmeyer The Journal of experimental medicine 178 (6), 2089-2096, 1993 | 209 | 1993 |
Transgenic expression of stromal cell-derived factor-1/CXC chemokine ligand 12 enhances myeloid progenitor cell survival/antiapoptosis in vitro in response to growth factor … HE Broxmeyer, S Cooper, L Kohli, G Hangoc, Y Lee, C Mantel, DW Clapp, ... The Journal of Immunology 170 (1), 421-429, 2003 | 202 | 2003 |
Nf1 Regulates Hematopoietic Progenitor Cell Growth and Ras Signaling in Response to Multiple Cytokines YY Zhang, TA Vik, JW Ryder, EF Srour, T Jacks, K Shannon, ... The Journal of experimental medicine 187 (11), 1893-1902, 1998 | 181 | 1998 |
Nf1+/− mast cells induce neurofibroma like phenotypes through secreted TGF-β signaling FC Yang, S Chen, T Clegg, X Li, T Morgan, SA Estwick, J Yuan, W Khalaf, ... Human molecular genetics 15 (16), 2421-2437, 2006 | 166 | 2006 |
Loss of FancC Function Results in Decreased Hematopoietic Stem Cell Repopulating Ability LS Haneline, TA Gobbett, R Ramani, M Carreau, M Buchwald, MC Yoder, ... Blood, The Journal of the American Society of Hematology 94 (1), 1-8, 1999 | 166 | 1999 |
Functional analysis of leukemia-associated PTPN11 mutations in primary hematopoietic cells S Schubbert, K Lieuw, SL Rowe, CM Lee, XX Li, ML Loh, DW Clapp, ... Blood 106 (1), 311-317, 2005 | 164 | 2005 |
Hyperactivation of P21ras and the Hematopoietic-Specific Rho Gtpase, Rac2, Cooperate to Alter the Proliferation of Neurofibromin-Deficient Mast Cells in Vivo and … DA Ingram, K Hiatt, AJ King, L Fisher, R Shivakumar, C Derstine, ... The Journal of experimental medicine 194 (1), 57-70, 2001 | 159 | 2001 |