Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia K Brennand, JN Savas, Y Kim, N Tran, A Simone, K Hashimoto-Torii, ... Molecular psychiatry 20 (3), 361-368, 2015 | 426 | 2015 |
NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer B Salomé, JP Sfakianos, D Ranti, J Daza, C Bieber, A Charap, C Hammer, ... Cancer Cell 40 (9), 1027-1043. e9, 2022 | 59 | 2022 |
Myeloid cell–associated resistance to PD-1/PD-L1 blockade in urothelial cancer revealed through bulk and single-cell RNA sequencing L Wang, JP Sfakianos, KG Beaumont, G Akturk, A Horowitz, RP Sebra, ... Clinical Cancer Research 27 (15), 4287-4300, 2021 | 58 | 2021 |
Microfluidic cell culture RD Lowe, K Beaumont, A Karunakaran, N Marks, JM McEwen, MP White, ... US Patent 10,723,988, 2020 | 58 | 2020 |
PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes NM Wickramasinghe, D Sachs, B Shewale, DM Gonzalez, ... Cell Stem Cell 29 (4), 559-576. e7, 2022 | 50 | 2022 |
Hypoxic niches attract and sequester tumor-associated macrophages and cytotoxic T cells and reprogram them for immunosuppression A Sattiraju, S Kang, B Giotti, Z Chen, VJ Marallano, C Brusco, ... Immunity 56 (8), 1825-1843. e6, 2023 | 42 | 2023 |
Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection TWF Lung, D Charytonowicz, KG Beaumont, SS Shah, SH Sridhar, ... Cell metabolism 34 (5), 761-774. e9, 2022 | 41 | 2022 |
Genomic signature of Fanconi anaemia DNA repair pathway deficiency in cancer ALH Webster, MA Sanders, K Patel, R Dietrich, RJ Noonan, FP Lach, ... Nature 612 (7940), 495-502, 2022 | 39 | 2022 |
Plectin-containing, centrally localized focal adhesions exert traction forces in primary lung epithelial cells JL Eisenberg, KG Beaumont, D Takawira, SB Hopkinson, M Mrksich, ... Journal of cell science 126 (16), 3746-3755, 2013 | 25 | 2013 |
A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals C Schaniel, P Dhanan, B Hu, Y Xiong, T Raghunandan, DM Gonzalez, ... Stem cell reports 16 (12), 3036-3049, 2021 | 21 | 2021 |
Micropatterning facilitates the long‐term growth and analysis of iPSC‐derived individual human neurons and neuronal networks LF Burbulla, KG Beaumont, M Mrksich, D Krainc Advanced healthcare materials 5 (15), 1894-1903, 2016 | 21 | 2016 |
High-resolution transcriptomics informs glial pathology in human temporal lobe epilepsy B Pai, J Tome-Garcia, WS Cheng, G Nudelman, KG Beaumont, S Ghatan, ... Acta neuropathologica communications 10 (1), 149, 2022 | 19 | 2022 |
Covalently modified surfaces, kits, and methods of preparation and use RD Lowe, AJ Mastroianni, MP White, GG Lavieu, KG Beaumont US Patent 11,007,520, 2021 | 19 | 2021 |
Functional effects of cardiomyocyte injury in COVID-19 MM Siddiq, AT Chan, L Miorin, AS Yadaw, KG Beaumont, T Kehrer, ... Journal of Virology 96 (2), e01063-21, 2022 | 18 | 2022 |
Molecular profiling of coronavirus disease 2019 (COVID-19) autopsies uncovers novel disease mechanisms E Pujadas, M Beaumont, H Shah, N Schrode, N Francoeur, S Shroff, ... The American Journal of Pathology 191 (12), 2064-2071, 2021 | 17 | 2021 |
An atlas of late prenatal human neurodevelopment resolved by single-nucleus transcriptomics SI Ramos, ZM Mussa, EN Falk, B Pai, B Giotti, K Allette, P Cai, F Dekio, ... Nature communications 13 (1), 7671, 2022 | 14 | 2022 |
Single-cell transcriptomic atlas of the human substantia nigra in Parkinson’s disease Q Wang, M Wang, I Choi, L Ho, K Farrell, KG Beaumont, R Sebra, ... Biorxiv, 2022.03. 25.485846, 2022 | 14 | 2022 |
The mechanostability of isolated focal adhesions is strongly dependent on pH KG Beaumont, M Mrksich Chemistry & biology 19 (6), 711-720, 2012 | 14 | 2012 |
A distal lung organoid model to study interstitial lung disease, viral infection and human lung development I Matkovic Leko, RT Schneider, TA Thimraj, N Schrode, D Beitler, HY Liu, ... Nature Protocols 18 (7), 2283-2312, 2023 | 12 | 2023 |
Limited Mitochondrial Activity Coupled With Strong Expression of CD34, CD90 and EPCR Determines the Functional Fitness of ex vivo Expanded Human … L Papa, M Djedaini, TC Martin, M Zangui, KG Beaumont, R Sebra, ... Frontiers in Cell and Developmental Biology 8, 592348, 2020 | 11 | 2020 |