Mitochondrial quality control as a key determinant of cell survival L Sedlackova, VI Korolchuk Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1866 (4), 575-587, 2019 | 127 | 2019 |
mTORC1 activity is supported by spatial association with focal adhesions Y Rabanal-Ruiz, A Byron, A Wirth, R Madsen, L Sedlackova, G Hewitt, ... The Journal of cell biology 220 (5), 2021 | 52 | 2021 |
Alpha-synuclein post-translational modifications: implications for pathogenesis of lewy body disorders NO Manzanza, L Sedlackova, RN Kalaria Frontiers in aging neuroscience 13, 690293, 2021 | 51 | 2021 |
Autophagy promotes cell survival by maintaining NAD levels T Kataura, L Sedlackova, EG Otten, R Kumari, D Shapira, F Scialo, ... Developmental cell 57 (22), 2584-2598. e11, 2022 | 44 | 2022 |
The crosstalk of NAD, ROS and autophagy in cellular health and ageing L Sedlackova, VI Korolchuk Biogerontology 21 (3), 381-397, 2020 | 33 | 2020 |
The pROS of autophagy in neuronal health L Sedlackova, G Kelly, VI Korolchuk Journal of molecular biology 432 (8), 2546-2559, 2020 | 23 | 2020 |
NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency C Sun, E Seranova, MA Cohen, M Chipara, J Roberts, D Astuti, ... Cell reports 42 (5), 2023 | 16 | 2023 |
Autophagy promotes cell and organismal survival by maintaining NAD (H) pools L Sedlackova, EG Otten, F Scialo, D Shapira, T Kataura, B Carroll, ... Biorxiv, 2020.01. 31.928424, 2020 | 6 | 2020 |
Metabolic function of autophagy is essential for cell survival L Sedlackova, T Kataura, S Sarkar, VI Korolchuk Autophagy 19 (8), 2395-2397, 2023 | 3 | 2023 |
Systematic mapping of organism-scale gene-regulatory networks in aging using population asynchrony M Eder, OMF Martin, N Oswal, L Sedlackova, C Moutinho, ... Cell, 2024 | | 2024 |
Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models T Kataura, L Sedlackova, C Sun, G Kocak, N Wilson, P Banks, F Hayat, ... Cell death & disease 15 (5), 382, 2024 | | 2024 |
High-Throughput Behavioral Aging and Lifespan Assays Using the Lifespan Machine. L Sedlackova, N Oswal, N Stroustrup Journal of Visualized Experiments: Jove, 2024 | | 2024 |
Author Spotlight: Automated Lifespan Monitoring–Discovering Aging Dynamics with the Lifespan Machine A Del Carmen-Fabregat, L Sedlackova, N Oswal, N Stroustrup JoVE (Journal of Visualized Experiments), e65462, 2024 | | 2024 |
Autophagy promotes cell survival by maintaining NAD (H) levels L Sedlackova, T Kataura, E Seranova, C Sun, E Otten, M Cohen, ... | | 2021 |
Study of the effects of macroautophagy deficiency on mitochondrial function, energy metabolism and cell fate L Sedlackova Newcastle University, 2020 | | 2020 |
Autophagy is Required for the Maintenance of NAD T Kataura, L Sedlackova, EG Otten, D Shapira, F Scialo, R Stefanatos, ... | | |