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Philip Schmiege
Philip Schmiege
在 utsouthwestern.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Structures of human Patched and its complex with native palmitoylated sonic hedgehog
X Qi, P Schmiege, E Coutavas, J Wang, X Li
Nature 560 (7716), 128-132, 2018
1772018
Human TRPML1 channel structures in open and closed conformations
P Schmiege, M Fine, G Blobel, X Li
Nature 550, 366-370, 2017
1462017
Two Patched molecules engage distinct sites on Hedgehog yielding a signaling-competent complex
X Qi, P Schmiege, E Coutavas, X Li
Science 362 (6410), eaas8843, 2018
1242018
3.3 Å structure of Niemann–Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport
X Li, F Lu, MN Trinh, P Schmiege, J Seemann, J Wang, G Blobel
Proceedings of the National Academy of Sciences 114 (34), 9116-9121, 2017
1052017
Structural basis for PtdInsP2-mediated human TRPML1 regulation
M Fine, P Schmiege, X Li
Nature Communications 9 (1), 4192, 2018
752018
Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1
Y Ren, P Schmiege, G Blobel
Elife 6, e20070, 2017
372017
Anemonefish personalities influence the strength of mutualistic interactions with host sea anemones
PFP Schmiege, CC D’Aloia, PM Buston
Marine Biology 164, 1-9, 2017
302017
Marked structural rearrangement of mannose 6-phosphate/IGF2 receptor at different pH environments
R Wang, X Qi, P Schmiege, E Coutavas, X Li
Science Advances 6 (7), eaaz1466, 2020
252020
Atomic insights into ML-SI3 mediated human TRPML1 inhibition
P Schmiege, M Fine, X Li
Structure 29 (11), 1295-1302. e3, 2021
192021
Structure and mechanism of human cystine exporter cystinosin
X Guo, P Schmiege, TE Assafa, R Wang, Y Xu, L Donnelly, M Fine, X Ni, ...
Cell 185 (20), 3739-3752. e18, 2022
172022
The regulatory mechanism of mammalian TRPML s revealed by cryo‐EM
P Schmiege, M Fine, X Li
The FEBS journal 285 (14), 2579-2585, 2018
82018
Expression, Purification, and Structure Determination of Human PTCH1–HH-N Complexes
X Qi, P Schmiege, L Esparza, X Li
Hedgehog Signaling: Methods and Protocols, 107-120, 2022
22022
Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake
T Long, D Li, G Vale, Y Jiang, P Schmiege, ZJ Yang, JG McDonald, X Li
Cell, 2024
2024
Structure and inhibition of the human lysosomal transporter Sialin
P Schmiege, L Donnelly, N Elghobashi-Meinhardt, CH Lee, X Li
Nature Communications 15 (1), 4386, 2024
2024
Anti-human cystinosin antibodies and methods of use thereof
P Schmiege, L Donnelly, X Li
US Patent App. 18/340,608, 2024
2024
Behavioral traits of anemonefish affect the anemone-anemonefish mutualism
PFP Schmiege, PM Buston
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