Structures of human Patched and its complex with native palmitoylated sonic hedgehog X Qi, P Schmiege, E Coutavas, J Wang, X Li Nature 560 (7716), 128-132, 2018 | 177 | 2018 |
Human TRPML1 channel structures in open and closed conformations P Schmiege, M Fine, G Blobel, X Li Nature 550, 366-370, 2017 | 146 | 2017 |
Two Patched molecules engage distinct sites on Hedgehog yielding a signaling-competent complex X Qi, P Schmiege, E Coutavas, X Li Science 362 (6410), eaas8843, 2018 | 124 | 2018 |
3.3 Å structure of Niemann–Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport X Li, F Lu, MN Trinh, P Schmiege, J Seemann, J Wang, G Blobel Proceedings of the National Academy of Sciences 114 (34), 9116-9121, 2017 | 105 | 2017 |
Structural basis for PtdInsP2-mediated human TRPML1 regulation M Fine, P Schmiege, X Li Nature Communications 9 (1), 4192, 2018 | 75 | 2018 |
Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1 Y Ren, P Schmiege, G Blobel Elife 6, e20070, 2017 | 37 | 2017 |
Anemonefish personalities influence the strength of mutualistic interactions with host sea anemones PFP Schmiege, CC D’Aloia, PM Buston Marine Biology 164, 1-9, 2017 | 30 | 2017 |
Marked structural rearrangement of mannose 6-phosphate/IGF2 receptor at different pH environments R Wang, X Qi, P Schmiege, E Coutavas, X Li Science Advances 6 (7), eaaz1466, 2020 | 25 | 2020 |
Atomic insights into ML-SI3 mediated human TRPML1 inhibition P Schmiege, M Fine, X Li Structure 29 (11), 1295-1302. e3, 2021 | 19 | 2021 |
Structure and mechanism of human cystine exporter cystinosin X Guo, P Schmiege, TE Assafa, R Wang, Y Xu, L Donnelly, M Fine, X Ni, ... Cell 185 (20), 3739-3752. e18, 2022 | 17 | 2022 |
The regulatory mechanism of mammalian TRPML s revealed by cryo‐EM P Schmiege, M Fine, X Li The FEBS journal 285 (14), 2579-2585, 2018 | 8 | 2018 |
Expression, Purification, and Structure Determination of Human PTCH1–HH-N Complexes X Qi, P Schmiege, L Esparza, X Li Hedgehog Signaling: Methods and Protocols, 107-120, 2022 | 2 | 2022 |
Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake T Long, D Li, G Vale, Y Jiang, P Schmiege, ZJ Yang, JG McDonald, X Li Cell, 2024 | | 2024 |
Structure and inhibition of the human lysosomal transporter Sialin P Schmiege, L Donnelly, N Elghobashi-Meinhardt, CH Lee, X Li Nature Communications 15 (1), 4386, 2024 | | 2024 |
Anti-human cystinosin antibodies and methods of use thereof P Schmiege, L Donnelly, X Li US Patent App. 18/340,608, 2024 | | 2024 |
Behavioral traits of anemonefish affect the anemone-anemonefish mutualism PFP Schmiege, PM Buston | | |