Interleukin-1β induces mtDNA release to activate innate immune signaling via cGAS-STING LD Aarreberg, K Esser-Nobis, C Driscoll, A Shuvarikov, JA Roby, M Gale Molecular cell 74 (4), 801-815. e6, 2019 | 281 | 2019 |
Noncoding subgenomic flavivirus RNA: multiple functions in West Nile virus pathogenesis and modulation of host responses JA Roby, GP Pijlman, J Wilusz, AA Khromykh Viruses 6 (2), 404-427, 2014 | 168 | 2014 |
Congenital Zika virus infection as a silent pathology with loss of neurogenic output in the fetal brain KM Adams Waldorf, BR Nelson, JE Stencel-Baerenwald, C Studholme, ... Nature medicine 24 (3), 368-374, 2018 | 151 | 2018 |
Post-translational regulation and modifications of flavivirus structural proteins JA Roby, YX Setoh, RA Hall, AA Khromykh Journal of General Virology 96 (Pt_7), 1551-1569, 2015 | 138 | 2015 |
Functional non-coding RNAs derived from the flavivirus 3′ untranslated region BD Clarke, JA Roby, A Slonchak, AA Khromykh Virus research 206, 53-61, 2015 | 133 | 2015 |
RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions J Schwerk, FW Soveg, AP Ryan, KR Thomas, LD Hatfield, S Ozarkar, ... Nature immunology 20 (12), 1610-1620, 2019 | 94 | 2019 |
Comparative analysis of African and Asian lineage-derived Zika virus strains reveals differences in activation of and sensitivity to antiviral innate immunity K Esser-Nobis, LD Aarreberg, JA Roby, MR Fairgrieve, R Green, ... Journal of virology 93 (13), 10.1128/jvi. 00640-19, 2019 | 78 | 2019 |
Zika virus and the nonmicrocephalic fetus: why we should still worry CL Walker, MTE Little, JA Roby, B Armistead, M Gale Jr, L Rajagopal, ... American journal of obstetrics and gynecology 220 (1), 45-56, 2019 | 67 | 2019 |
Endomembrane targeting of human OAS1 p46 augments antiviral activity FW Soveg, J Schwerk, NS Gokhale, K Cerosaletti, JR Smith, ... Elife 10, e71047, 2021 | 53 | 2021 |
Rapid reversal of innate immune dysregulation in blood of patients and livers of humanized mice with HCV following DAA therapy MA Burchill, JA Roby, N Crochet, M Wind-Rotolo, AE Stone, MG Edwards, ... PloS one 12 (10), e0186213, 2017 | 45 | 2017 |
Flavivirus nonstructural protein NS5 dysregulates HSP90 to broadly inhibit JAK/STAT signaling JA Roby, K Esser-Nobis, EC Dewey-Verstelle, MR Fairgrieve, J Schwerk, ... Cells 9 (4), 899, 2020 | 39 | 2020 |
Immune evasion strategies used by zika virus to infect the fetal eye and brain BR Nelson, JA Roby, WB Dobyns, L Rajagopal, M Gale Jr, ... Viral immunology 33 (1), 22-37, 2020 | 26 | 2020 |
Flavivirus replication and assembly JA Roby, A Funk, AA Khromykh Caister Academic Press, 2012 | 24* | 2012 |
A scoping review of African swine fever virus spread between domestic and free‐living pigs VJ Brookes, TE Barrett, MP Ward, JA Roby, M Hernandez‐Jover, ... Transboundary and Emerging Diseases 68 (5), 2643-2656, 2021 | 22 | 2021 |
The intrinsically disordered W protein is multifunctional during Henipavirus infection, disrupting host signalling pathways and nuclear import S Tsimbalyuk, EM Cross, M Hoad, CM Donnelly, JA Roby, JK Forwood Cells 9 (8), 1913, 2020 | 19 | 2020 |
MERS-CoV ORF4b employs an unusual binding mechanism to target IMPα and block innate immunity TS Munasinghe, MR Edwards, S Tsimbalyuk, OA Vogel, KM Smith, ... Nature Communications 13 (1), 1604, 2022 | 17 | 2022 |
Structural perspectives of beak and feather disease virus and porcine circovirus proteins BK Nath, S Das, JA Roby, S Sarker, D Luque, SR Raidal, JK Forwood Viral Immunology 34 (1), 49-59, 2021 | 17 | 2021 |
Increased expression of capsid protein in trans enhances production of single-round infectious particles by West Nile virus DNA vaccine candidate JA Roby, H Bielefeldt-Ohmann, NA Prow, DC Chang, RA Hall, ... Journal of General Virology 95 (10), 2176-2191, 2014 | 17 | 2014 |
Structural characterization of porcine adeno-associated virus capsid protein with nuclear trafficking protein importin alpha reveals a bipartite nuclear localization signal M Hoad, EM Cross, CM Donnelly, S Sarker, JA Roby, JK Forwood Viruses 15 (2), 315, 2023 | 10 | 2023 |
West Nile virus genome with glycosylated envelope protein and deletion of alpha helices 1, 2, and 4 in the capsid protein is noninfectious and efficiently secretes subviral … JA Roby, RA Hall, AA Khromykh Journal of Virology 87 (23), 13063-13069, 2013 | 10 | 2013 |