HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients W Guo, M Naujock, L Fumagalli, T Vandoorne, P Baatsen, R Boon, ... Nature communications 8 (1), 861, 2017 | 364 | 2017 |
Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines R Boon, M Kumar, T Tricot, I Elia, L Ordovas, F Jacobs, J One, J De Smedt, ... Nature communications 11 (1), 1393, 2020 | 109 | 2020 |
Comparing in vitro human liver models to in vivo human liver using RNA-Seq R Gupta, Y Schrooders, D Hauser, M van Herwijnen, W Albrecht, ... Archives of toxicology 95, 573-589, 2021 | 73 | 2021 |
Therapeutic modalities and novel approaches in regenerative medicine for COVID-19 R Ramezankhani, R Solhi, A Memarnejadian, F Nami, SMR Hashemian, ... International journal of antimicrobial agents 56 (6), 106208, 2020 | 42 | 2020 |
A fully defined matrix to support a pluripotent stem cell derived multi-cell-liver steatohepatitis and fibrosis model M Kumar, B Toprakhisar, M Van Haele, A Antoranz, R Boon, F Chesnais, ... Biomaterials 276, 121006, 2021 | 26 | 2021 |
Current status and challenges of human induced pluripotent stem cell-derived liver models in drug discovery T Tricot, CM Verfaillie, M Kumar Cells 11 (3), 442, 2022 | 24 | 2022 |
Human stem cell-derived hepatocyte-like cells support Zika virus replication and provide a relevant model to assess the efficacy of potential antivirals T Tricot, N Helsen, SJF Kaptein, J Neyts, CM Verfaillie PloS one 13 (12), e0209097, 2018 | 24 | 2018 |
Recent advances in lineage differentiation from stem cells: hurdles and opportunities? J Terryn, T Tricot, M Gajjar, C Verfaillie F1000Research 7, 2018 | 24 | 2018 |
Dystrophin deficiency leads to dysfunctional glutamate clearance in iPSC derived astrocytes AM Patel, K Wierda, L Thorrez, M van Putten, J De Smedt, L Ribeiro, ... Translational psychiatry 9 (1), 200, 2019 | 21 | 2019 |
Alternative cell sources for liver parenchyma repopulation: where do we stand? T Tricot, J De Boeck, C Verfaillie Cells 9 (3), 566, 2020 | 17 | 2020 |
CRISPR/Cas9 screen in human iPSC‐derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity W Guo, H Wang, A Kumar Tharkeshwar, J Couthouis, E Braems, ... Alzheimer's & Dementia 19 (4), 1245-1259, 2023 | 15 | 2023 |
HiPSC-derived hepatocyte-like cells can be used as a model for Transcriptomics-based study of chemical toxicity S Ghosh, J De Smedt, T Tricot, S Proença, M Kumar, F Nami, ... Toxics 10 (1), 1, 2021 | 7 | 2021 |
Patient-specific induced pluripotent stem cell-derived hepatocyte-like cells as a model to study autosomal recessive hypercholesterolemia P Nikasa, T Tricot, N Mahdieh, H Baharvand, M Totonchi, MS Hejazi, ... Stem Cells and Development 30 (14), 714-724, 2021 | 7 | 2021 |
A Novel UPLC-MS metabolomic analysis-based strategy to monitor the course and extent of iPSC differentiation to hepatocytes M Moreno-Torres, M Kumar, G Garcia-Llorens, G Quintas, T Tricot, ... Journal of Proteome Research 21 (3), 702-712, 2022 | 4 | 2022 |
Metabolically improved stem cell derived hepatocyte-like cells support HBV life cycle and are a promising tool for HBV studies and antiviral drug screenings T Tricot, HJ Thibaut, K Abbasi, R Boon, N Helsen, M Kumar, J Neyts, ... Biomedicines 10 (2), 268, 2022 | 3 | 2022 |