| The journey of DDR1 and DDR2 kinase inhibitors as rising stars in the fight against cancer A Elkamhawy, Q Lu, H Nada, J Woo, G Quan, K Lee International journal of molecular sciences 22 (12), 6535, 2021 | 58 | 2021 |
| Emerging therapeutic strategies for Parkinson’s disease and future prospects: A 2021 update NA Gouda, A Elkamhawy, J Cho Biomedicines 10 (2), 371, 2022 | 45 | 2022 |
| Identification of novel discoidin domain receptor 1 (DDR1) inhibitors using E-pharmacophore modeling, structure-based virtual screening, molecular dynamics simulation and MM … H Nada, K Lee, L Gotina, AN Pae, A Elkamhawy Computers in Biology and Medicine 142, 105217, 2022 | 42 | 2022 |
| Novel quinazoline-urea analogues as modulators for Aβ-induced mitochondrial dysfunction: Design, synthesis, and molecular docking study A Elkamhawy, J Lee, BG Park, I Park, AN Pae, EJ Roh European journal of medicinal chemistry 84, 466-475, 2014 | 41 | 2014 |
| Targeting EGFR/HER2 tyrosine kinases with a new potent series of 6-substituted 4-anilinoquinazoline hybrids: Design, synthesis, kinase assay, cell-based assay, and molecular … A Elkamhawy, AK Farag, ANI Viswanath, TM Bedair, DG Leem, KT Lee, ... Bioorganic & Medicinal Chemistry Letters 25 (22), 5147-5154, 2015 | 40 | 2015 |
| EGFR inhibitors from cancer to inflammation: Discovery of 4-fluoro-N-(4-(3-(trifluoromethyl) phenoxy) pyrimidin-5-yl) benzamide as a novel anti-inflammatory EGFR inhibitor A Elkamhawy, AHE Hassan, S Paik, YS Lee, HH Lee, JS Shin, KT Lee, ... Bioorganic chemistry 86, 112-118, 2019 | 38 | 2019 |
| Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents S Kang, JM Lee, B Jeon, A Elkamhawy, S Paik, J Hong, SJ Oh, SH Paek, ... European Journal of Medicinal Chemistry 151, 186-198, 2018 | 34 | 2018 |
| Diabetes mellitus: Classification, mediators, and complications; A gate to identify potential targets for the development of new effective treatments SA Antar, NA Ashour, M Sharaky, M Khattab, NA Ashour, RT Zaid, EJ Roh, ... Biomedicine & Pharmacotherapy 168, 115734, 2023 | 32 | 2023 |
| Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insights MM Al-Sanea, A Elkamhawy, S Paik, K Lee, AM El Kerdawy, BSN Abbas, ... Bioorganic & medicinal chemistry 28 (13), 115525, 2020 | 32 | 2020 |
| Novel LCK/FMS inhibitors based on phenoxypyrimidine scaffold as potential treatment for inflammatory disorders AK Farag, A Elkamhawy, AM Londhe, KT Lee, AN Pae, EJ Roh European Journal of Medicinal Chemistry 141, 657-675, 2017 | 31 | 2017 |
| Ligand-based design on the dog-bone-shaped BIBR1532 pharmacophoric features and synthesis of novel analogues as promising telomerase inhibitors with in vitro and in vivo … AA Al-Karmalawy, MS Nafie, MA Shaldam, AA Elmaaty, SA Antar, ... Journal of Medicinal Chemistry 66 (1), 777-792, 2022 | 30 | 2022 |
| Thiazolidine-2, 4-dione-based irreversible allosteric IKK-β kinase inhibitors: Optimization into in vivo active anti-inflammatory agents A Elkamhawy, N youn Kim, AHE Hassan, J Park, S Paik, JE Yang, KS Oh, ... European Journal of Medicinal Chemistry 188, 111955, 2020 | 29 | 2020 |
| Synthesis and evaluation of 2-(3-arylureido) pyridines and 2-(3-arylureido) pyrazines as potential modulators of Aβ-induced mitochondrial dysfunction in Alzheimer's disease A Elkamhawy, J Park, AHE Hassan, AN Pae, J Lee, BG Park, EJ Roh European Journal of Medicinal Chemistry 144, 529-543, 2018 | 29 | 2018 |
| Discovery of a broad spectrum antiproliferative agent with selectivity for DDR1 kinase: Cell line-based assay, kinase panel, molecular docking, and toxicity studies A Elkamhawy, J Park, NC Cho, T Sim, AN Pae, EJ Roh Journal of Enzyme Inhibition and Medicinal Chemistry 31 (1), 158-166, 2016 | 27 | 2016 |
| Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino) benzenesulfonamides as carbonic anhydrase isoforms I and II inhibitors MM Al-Sanea, A Elkamhawy, S Paik, S Bua, S Ha Lee, MA Abdelgawad, ... Journal of enzyme inhibition and medicinal chemistry 34 (1), 1457-1464, 2019 | 26 | 2019 |
| Hit discovery of 4-amino-N-(4-(3-(trifluoromethyl) phenoxy) pyrimidin-5-yl) benzamide: A novel EGFR inhibitor from a designed small library A Elkamhawy, S Paik, AHE Hassan, YS Lee, EJ Roh Bioorganic Chemistry 75, 393-405, 2017 | 26 | 2017 |
| Design, synthesis, biological evaluation and molecular modelling of 2-(2-aryloxyphenyl)-1, 4-dihydroisoquinolin-3 (2H)-ones: A novel class of TSPO ligands modulating amyloid-β … A Elkamhawy, J Park, AHE Hassan, AN Pae, J Lee, BG Park, S Paik, J Do, ... European journal of pharmaceutical sciences 104, 366-381, 2017 | 26 | 2017 |
| Discovery of 1-(3-(benzyloxy) pyridin-2-yl)-3-(2-(piperazin-1-yl) ethyl) urea: A new modulator for amyloid beta-induced mitochondrial dysfunction A Elkamhawy, J Park, AHE Hassan, H Ra, AN Pae, J Lee, BG Park, ... European journal of medicinal chemistry 128, 56-69, 2017 | 25 | 2017 |
| Discovery of potent and selective cytotoxic activity of new quinazoline-ureas against TMZ-resistant glioblastoma multiforme (GBM) A Elkamhawy, ANI Viswanath, AN Pae, HY Kim, JC Heo, WK Park, ... European journal of medicinal chemistry 103, 210-222, 2015 | 25 | 2015 |
| Design, synthesis and biological evaluation of novel thiazolidinedione derivatives as irreversible allosteric IKK-β modulators A Elkamhawy, N youn Kim, AHE Hassan, J Park, JE Yang, KS Oh, BH Lee, ... European Journal of Medicinal Chemistry 157, 691-704, 2018 | 23 | 2018 |
