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Peter J. Chen
Peter J. Chen
在 alumni.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Search-and-replace genome editing without double-strand breaks or donor DNA
AV Anzalone, PB Randolph, JR Davis, AA Sousa, LW Koblan, JM Levy, ...
Nature 576 (7785), 149-157, 2019
35402019
Enhanced prime editing systems by manipulating cellular determinants of editing outcomes
PJ Chen, JA Hussmann, J Yan, F Knipping, P Ravisankar, PF Chen, ...
Cell 184 (22), 5635-5652. e29, 2021
4362021
Engineered pegRNAs improve prime editing efficiency
JW Nelson, PB Randolph, SP Shen, KA Everette, PJ Chen, AV Anzalone, ...
Nature biotechnology 40 (3), 402-410, 2022
3842022
Programmable m6A modification of cellular RNAs with a Cas13-directed methyltransferase
C Wilson, PJ Chen, Z Miao, DR Liu
Nature biotechnology 38 (12), 1431-1440, 2020
2082020
Prime editing for precise and highly versatile genome manipulation
PJ Chen, DR Liu
Nature Reviews Genetics 24 (3), 161-177, 2023
1812023
Designing and executing prime editing experiments in mammalian cells
JL Doman, AA Sousa, PB Randolph, PJ Chen, DR Liu
Nature protocols 17 (11), 2431-2468, 2022
542022
Efficient prime editing in mouse brain, liver and heart with dual AAVs
JR Davis, S Banskota, JM Levy, GA Newby, X Wang, AV Anzalone, ...
Nature biotechnology 42 (2), 253-264, 2024
532024
Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice
KA Everette, GA Newby, RM Levine, K Mayberry, Y Jang, T Mayuranathan, ...
Nature biomedical engineering 7 (5), 616-628, 2023
462023
In vivo HSC prime editing rescues sickle cell disease in a mouse model
C Li, A Georgakopoulou, GA Newby, PJ Chen, KA Everette, K Paschoudi, ...
Blood, The Journal of the American Society of Hematology 141 (17), 2085-2099, 2023
462023
Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus
Q Ji, PJ Chen, G Qin, X Deng, Z Hao, Z Wawrzak, WS Yeo, JW Quang, ...
Nature communications 7 (1), 11000, 2016
372016
Rna programmable epigenetic rna modifiers and uses thereof
DR Liu, CG Wilson, PJ Chen
US Patent App. 17/259,147, 2022
142022
Continuous evolution of compact protein degradation tags regulated by selective molecular glues
JAM Mercer, SJ DeCarlo, SS Roy Burman, V Sreekanth, AT Nelson, ...
Science 383 (6688), eadk4422, 2024
42024
Author Correction: Engineered pegRNAs improve prime editing efficiency
JW Nelson, PB Randolph, SP Shen, KA Everette, PJ Chen, AV Anzalone, ...
Nature biotechnology 40 (3), 432, 2022
42022
Efficient prime editing in two-cell mouse embryos using PEmbryo
RP Kim-Yip, R McNulty, B Joyce, A Mollica, PJ Chen, P Ravisankar, ...
Nature biotechnology, 1-9, 2024
32024
Prime editing guide rnas, compositions thereof, and methods of using the same
DR Liu, JW Nelson, PB Randolph, AV Anzalone, S Shen, K Everette, ...
US Patent App. 18/028,183, 2023
2023
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