| The major risk factors for Alzheimer’s disease: age, sex, and genes modulate the microglia response to Aβ plaques CS Frigerio, L Wolfs, N Fattorelli, N Thrupp, I Voytyuk, I Schmidt, ... Cell reports 27 (4), 1293-1306. e6, 2019 | 646 | 2019 |
| Spatial transcriptomics and in situ sequencing to study Alzheimer’s disease WT Chen, A Lu, K Craessaerts, B Pavie, CS Frigerio, N Corthout, X Qian, ... Cell 182 (4), 976-991. e19, 2020 | 616 | 2020 |
| Alteration of the micro RNA network during the progression of Alzheimer's disease P Lau, K Bossers, R Janky, E Salta, CS Frigerio, S Barbash, R Rothman, ... EMBO molecular medicine 5 (10), 1613-1634, 2013 | 498 | 2013 |
| Single-nucleus RNA-seq is not suitable for detection of microglial activation genes in humans N Thrupp, CS Frigerio, L Wolfs, NG Skene, N Fattorelli, S Poovathingal, ... Cell reports 32 (13), 2020 | 236 | 2020 |
| Stem-cell-derived human microglia transplanted in mouse brain to study human disease R Mancuso, J Van Den Daele, N Fattorelli, L Wolfs, S Balusu, O Burton, ... Nature neuroscience 22 (12), 2111-2116, 2019 | 218 | 2019 |
| The APP family of proteins: similarities and differences DM Walsh, AM Minogue, C Sala Frigerio, JV Fadeeva, W Wasco, ... Biochemical Society Transactions 35 (2), 416-420, 2007 | 176 | 2007 |
| Reduced expression of hsa-miR-27a-3p in CSF of patients with Alzheimer disease C Sala Frigerio, P Lau, E Salta, J Tournoy, K Bossers, R Vandenberghe, ... Neurology 81 (24), 2103-2106, 2013 | 171 | 2013 |
| Alzheimer's disease mechanisms and emerging roads to novel therapeutics C Sala Frigerio, B De Strooper Annual review of neuroscience 39 (1), 57-79, 2016 | 128 | 2016 |
| Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer’s disease S De Schepper, JZ Ge, G Crowley, LSS Ferreira, D Garceau, CE Toomey, ... Nature neuroscience 26 (3), 406-415, 2023 | 99 | 2023 |
| Restoring miR-132 expression rescues adult hippocampal neurogenesis and memory deficits in Alzheimer’s disease H Walgrave, S Balusu, S Snoeck, EV Eynden, K Craessaerts, N Thrupp, ... Cell Stem Cell 28 (10), 1805-1821. e8, 2021 | 98 | 2021 |
| Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation GG Borlikova, M Trejo, AJ Mably, JM Mc Donald, CS Frigerio, CM Regan, ... Neurobiology of aging 34 (5), 1315-1327, 2013 | 89 | 2013 |
| A genetic link between risk for Alzheimer's disease and severe COVID-19 outcomes via the OAS1 gene N Magusali, AC Graham, TM Piers, P Panichnantakul, U Yaman, M Shoai, ... Brain 144 (12), 3727-3741, 2021 | 87 | 2021 |
| On the identification of low allele frequency mosaic mutations in the brains of Alzheimer's disease patients CS Frigerio, P Lau, C Troakes, V Deramecourt, P Gele, P Van Loo, T Voet, ... Alzheimer's & Dementia 11 (11), 1265-1276, 2015 | 82 | 2015 |
| N-terminal extensions retard Aβ42 fibril formation but allow cross-seeding and coaggregation with Aβ42 O Szczepankiewicz, B Linse, G Meisl, E Thulin, B Frohm, C Sala Frigerio, ... Journal of the American Chemical Society 137 (46), 14673-14685, 2015 | 74 | 2015 |
| Variance in the identification of microRNAs deregulated in Alzheimer's disease and possible role of lincRNAs in the pathology: the need of larger datasets P Lau, CS Frigerio, B De Strooper Ageing research reviews 17, 43-53, 2014 | 61 | 2014 |
| PLD3 gene and processing of APP P Fazzari, K Horre, AM Arranz, CS Frigerio, T Saito, TC Saido, ... Nature 541 (7638), E1-E2, 2017 | 50 | 2017 |
| Single-cell quantification of mRNA expression in the human brain S Jolly, V Lang, VH Koelzer, C Sala Frigerio, L Magno, PC Salinas, ... Scientific reports 9 (1), 12353, 2019 | 49 | 2019 |
| PEN–2 gene mutation in a familial Alzheimer’s disease case C Sala Frigerio, P Piscopo, E Calabrese, A Crestini, L Malvezzi Campeggi, ... Journal of neurology 252 (9), 1033-1036, 2005 | 45 | 2005 |
| A self-organizing miR-132/Ctbp2 circuit regulates bimodal notch signals and glial progenitor fate choice during spinal cord maturation E Salta, P Lau, CS Frigerio, M Coolen, L Bally-Cuif, B De Strooper Developmental cell 30 (4), 423-436, 2014 | 37 | 2014 |
| β‐Secretase cleavage is not required for generation of the intracellular C‐terminal domain of the amyloid precursor family of proteins C Sala Frigerio, JV Fadeeva, AM Minogue, M Citron, F Van Leuven, ... The FEBS journal 277 (6), 1503-1518, 2010 | 29 | 2010 |
