| Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets EZ Macosko, A Basu, R Satija, J Nemesh, K Shekhar, M Goldman, I Tirosh, ... Cell 161 (5), 1202-1214, 2015 | 6972 | 2015 |
| Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma AP Patel, I Tirosh, JJ Trombetta, AK Shalek, SM Gillespie, H Wakimoto, ... Science 344 (6190), 1396-1401, 2014 | 4439 | 2014 |
| Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq I Tirosh, B Izar, SM Prakadan, MH Wadsworth, D Treacy, JJ Trombetta, ... Science 352 (6282), 189-196, 2016 | 3983 | 2016 |
| Single-cell transcriptomic analysis of primary and metastatic tumor ecosystems in head and neck cancer SV Puram, I Tirosh, AS Parikh, AP Patel, K Yizhak, S Gillespie, C Rodman, ... Cell 171 (7), 1611-1624. e24, 2017 | 1923 | 2017 |
| An integrative model of cellular states, plasticity, and genetics for glioblastoma C Neftel, J Laffy, MG Filbin, T Hara, ME Shore, GJ Rahme, AR Richman, ... Cell 178 (4), 835-849. e21, 2019 | 1764 | 2019 |
| A single-cell survey of the small intestinal epithelium AL Haber, M Biton, N Rogel, RH Herbst, K Shekhar, C Smillie, G Burgin, ... Nature 551 (7680), 333-339, 2017 | 1412 | 2017 |
| Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial DB Keskin, AJ Anandappa, J Sun, I Tirosh, ND Mathewson, S Li, ... Nature 565 (7738), 234-239, 2019 | 1158 | 2019 |
| A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ... Cell 175 (4), 984-997. e24, 2018 | 1061 | 2018 |
| Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma I Tirosh, AS Venteicher, C Hebert, LE Escalante, AP Patel, K Yizhak, ... Nature 539 (7628), 309-313, 2016 | 1002 | 2016 |
| Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells ML Suvà, E Rheinbay, SM Gillespie, AP Patel, H Wakimoto, SD Rabkin, ... Cell 157 (3), 580-594, 2014 | 930 | 2014 |
| Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq AS Venteicher, I Tirosh, C Hebert, K Yizhak, C Neftel, MG Filbin, ... Science 355 (6332), eaai8478, 2017 | 870 | 2017 |
| Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells MS Kowalczyk, I Tirosh, D Heckl, TN Rao, A Dixit, BJ Haas, RK Schneider, ... Genome research 25 (12), 1860-1872, 2015 | 694 | 2015 |
| Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq MG Filbin, I Tirosh, V Hovestadt, MKL Shaw, LE Escalante, ... Science 360 (6386), 331-335, 2018 | 562 | 2018 |
| A genome-wide CRISPR screen in primary immune cells to dissect regulatory networks O Parnas, M Jovanovic, TM Eisenhaure, RH Herbst, A Dixit, CJ Ye, ... Cell 162 (3), 675-686, 2015 | 520 | 2015 |
| T helper cell cytokines modulate intestinal stem cell renewal and differentiation M Biton, AL Haber, N Rogel, G Burgin, S Beyaz, A Schnell, O Ashenberg, ... Cell 175 (5), 1307-1320. e22, 2018 | 474 | 2018 |
| Two strategies for gene regulation by promoter nucleosomes I Tirosh, N Barkai Genome research 18 (7), 1084-1091, 2008 | 459 | 2008 |
| A yeast hybrid provides insight into the evolution of gene expression regulation I Tirosh, S Reikhav, AA Levy, N Barkai Science 324 (5927), 659-662, 2009 | 441 | 2009 |
| Single-cell RNA sequencing in cancer: lessons learned and emerging challenges ML Suvà, I Tirosh Molecular cell 75 (1), 7-12, 2019 | 363 | 2019 |
| A single-cell landscape of high-grade serous ovarian cancer B Izar, I Tirosh, EH Stover, I Wakiro, MS Cuoco, I Alter, C Rodman, ... Nature medicine 26 (8), 1271-1279, 2020 | 334 | 2020 |
| Challenges and emerging directions in single-cell analysis GC Yuan, L Cai, M Elowitz, T Enver, G Fan, G Guo, R Irizarry, ... Genome biology 18, 1-8, 2017 | 332 | 2017 |
