Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells CX Liu, QQ Yin, HC Zhou, YL Wu, JX Pu, L Xia, W Liu, X Huang, T Jiang, ... Nature chemical biology 8 (5), 486-493, 2012 | 223 | 2012 |
Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors JH Kalin, M Wu, AV Gomez, Y Song, J Das, D Hayward, N Adejola, M Wu, ... Nature communications 9 (1), 53, 2018 | 206 | 2018 |
Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2 F Rao, J Cha, J Xu, R Xu, MS Vandiver, R Tyagi, R Tokhunts, ... Molecular cell 54 (1), 119-132, 2014 | 120 | 2014 |
Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex Y Song, L Dagil, L Fairall, N Robertson, M Wu, TJ Ragan, CG Savva, ... Cell Reports 30 (8), 2699-2711. e8, 2020 | 107 | 2020 |
Characterization of the polyoxin biosynthetic gene cluster from Streptomyces cacaoi and engineered production of polyoxin H W Chen, T Huang, X He, Q Meng, D You, L Bai, J Li, M Wu, R Li, Z Xie, ... Journal of Biological Chemistry 284 (16), 10627-10638, 2009 | 101 | 2009 |
Inositol polyphosphates intersect with signaling and metabolic networks via two distinct mechanisms M Wu, LS Chong, DH Perlman, AC Resnick, D Fiedler Proceedings of the National Academy of Sciences 113 (44), E6757-E6765, 2016 | 93 | 2016 |
Synthesis and characterization of non-hydrolysable diphosphoinositol polyphosphate messengers M Wu, BE Dul, AJ Trevisan, D Fiedler Chemical Science 4 (1), 405-410, 2013 | 80 | 2013 |
Inositol hexakisphosphate kinase 1 (IP6K1) activity is required for cytoplasmic dynein-driven transport M Chanduri, A Rai, AB Malla, M Wu, D Fiedler, R Mallik, R Bhandari Biochemical Journal 473 (19), 3031-3047, 2016 | 71 | 2016 |
Elucidating diphosphoinositol polyphosphate function with nonhydrolyzable analogues M Wu, LS Chong, S Capolicchio, HJ Jessen, AC Resnick, D Fiedler Angewandte Chemie International Edition 53 (28), 7192-7197, 2014 | 64 | 2014 |
A Novel Inositol Pyrophosphate Phosphatase in Saccharomyces cerevisiae Siw14 PROTEIN SELECTIVELY CLEAVES THE β-PHOSPHATE FROM 5-DIPHOSPHOINOSITOL PENTAKISPHOSPHATE (5PP-IP5) EA Steidle, LS Chong, M Wu, E Crooke, D Fiedler, AC Resnick, RJ Rolfes Journal of Biological Chemistry 291 (13), 6772-6783, 2016 | 60 | 2016 |
Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex M Wu, D Hayward, JH Kalin, Y Song, JWR Schwabe, PA Cole eLife 7, e37231, 2018 | 50 | 2018 |
Diverse nucleosome Site-Selectivity among histone deacetylase complexes ZA Wang, CJ Millard, CL Lin, JE Gurnett, M Wu, K Lee, L Fairall, ... Elife 9, e57663, 2020 | 48 | 2020 |
Combination targeting of the bromodomain and acetyltransferase active site of p300/CBP BE Zucconi, JL Makofske, DJ Meyers, Y Hwang, M Wu, MI Kuroda, ... Biochemistry 58 (16), 2133-2143, 2019 | 45 | 2019 |
Histone H2B Deacylation Selectivity: Exploring Chromatin’s Dark Matter with an Engineered Sortase ZA Wang, SD Whedon, M Wu, S Wang, EA Brown, A Anmangandla, ... Journal of the American Chemical Society 144 (8), 3360-3364, 2022 | 25 | 2022 |
Cellular cations control conformational switching of inositol pyrophosphate analogues A Hager, M Wu, H Wang, NW Brown Jr, SB Shears, N Veiga, D Fiedler Chemistry–A European Journal 22 (35), 12406-12414, 2016 | 23 | 2016 |
Structure of the yeast Swi/Snf complex in a nucleosome free state C Wang, Z Guo, X Zhan, F Yang, M Wu, X Zhang Nature communications 11 (1), 3398, 2020 | 17 | 2020 |
Structure of a SIN3–HDAC complex from budding yeast Z Guo, C Chu, Y Lu, X Zhang, Y Xiao, M Wu, S Gao, CCL Wong, X Zhan, ... Nature Structural & Molecular Biology 30 (6), 753-760, 2023 | 12 | 2023 |
2, 3, 6-Trideoxy sugar nucleotides: synthesis and stability M Wu, Q Meng, M Ge, L Bai, H Zhou Tetrahedron Letters 52 (44), 5799-5801, 2011 | 12 | 2011 |
Site‐Specific 5‐Formyl Cytosine Mediated DNA‐Histone Cross‐Links: Synthesis and Polymerase Bypass by Human DNA Polymerase η SS Pujari, M Wu, J Thomforde, ZA Wang, C Chao, NM Olson, L Erber, ... Angewandte Chemie International Edition 60 (51), 26489-26494, 2021 | 9 | 2021 |
A General Method to Edit Histone H3 Modifications on Chromatin Via Sortase‐Mediated Metathesis Q Yang, Y Gao, X Liu, Y Xiao, M Wu Angewandte Chemie International Edition 61 (52), e202209945, 2022 | 8 | 2022 |