Mitochondrial complex II is a source of the reserve respiratory capacity that is regulated by metabolic sensors and promotes cell survival J Pfleger, M He, M Abdellatif Cell death & disease 6 (7), e1835-e1835, 2015 | 243 | 2015 |
G protein-coupled receptor kinases as therapeutic targets in the heart J Pfleger, K Gresham, WJ Koch Nature Reviews Cardiology 16 (10), 612-622, 2019 | 135 | 2019 |
HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction M Wallner, DM Eaton, RM Berretta, L Liesinger, M Schittmayer, ... Science translational medicine 12 (525), eaay7205, 2020 | 92 | 2020 |
Acute targeting of general transcription factor IIB restricts cardiac hypertrophy via selective inhibition of gene transcription D Sayed, Z Yang, M He, JM Pfleger, M Abdellatif Circulation: Heart Failure 8 (1), 138-148, 2015 | 26 | 2015 |
G protein-coupled receptor kinase 2 contributes to impaired fatty acid metabolism in the failing heart J Pfleger, P Gross, J Johnson, RL Carter, E Gao, DG Tilley, SR Houser, ... Journal of molecular and cellular cardiology 123, 108-117, 2018 | 23 | 2018 |
Alteration of myocardial GRK2 produces a global metabolic phenotype BP Woodall, KS Gresham, MA Woodall, MC Valenti, A Cannavo, J Pfleger, ... JCI insight 4 (10), 2019 | 20 | 2019 |
Histone H3K9 butyrylation is regulated by dietary fat and stress via an Acyl-CoA dehydrogenase short chain-dependent mechanism Z Yang, M He, J Austin, J Pfleger, M Abdellatif Molecular metabolism 53, 101249, 2021 | 18 | 2021 |
Oxoglutarate dehydrogenase and acetyl-CoA acyltransferase 2 selectively associate with H2A. Z-occupied promoters and are required for histone modifications S Choi, J Pfleger, YH Jeon, Z Yang, M He, H Shin, D Sayed, S Astrof, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1862 (10), 194436, 2019 | 18 | 2019 |
Genomic binding patterns of forkhead box protein o1 reveal its unique role in cardiac hypertrophy J Pfleger, RC Coleman, J Ibetti, R Roy, ID Kyriazis, E Gao, K Drosatos, ... Circulation 142 (9), 882-898, 2020 | 13 | 2020 |
Transcriptional regulation mediated by H2A. Z via ANP32e-dependent inhibition of protein phosphatase 2A H Shin, M He, Z Yang, YH Jeon, J Pfleger, D Sayed, M Abdellatif Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1861 (5), 481-496, 2018 | 13 | 2018 |
Loss of dynamic regulation of G protein-coupled receptor kinase 2 by nitric oxide leads to cardiovascular dysfunction with aging M Lieu, CJ Traynham, C de Lucia, J Pfleger, M Piedepalumbo, R Roy, ... American Journal of Physiology-Heart and Circulatory Physiology 318 (5 …, 2020 | 10 | 2020 |
A peptide of the amino-terminus of GRK2 induces hypertrophy and yet elicits cardioprotection after pressure overload KM Bledzka, IH Manaserh, J Grondolsky, J Pfleger, R Roy, E Gao, ... Journal of Molecular and Cellular Cardiology 154, 137-153, 2021 | 9 | 2021 |
Adiponectin enhances the bioenergetics of cardiac myocytes via an AMPK-and succinate dehydrogenase-dependent mechanism YH Jeon, M He, J Austin, H Shin, J Pfleger, M Abdellatif Cellular signalling 78, 109866, 2021 | 9 | 2021 |
Measurements of Mitochondrial Respiration in Intact Cells, Permeabilized Cells, and Isolated Tissue Mitochondria Using the Seahorse XF Analyzer J Pfleger Mitochondria, 185-206, 2022 | 5 | 2022 |
Mitochondria: Methods and Protocols N Tomar Springer Nature, 2022 | 2 | 2022 |
Mitochondrial GRK2 is a Novel Regulator of Cardiac Energetics KM Ferrero, K Chuprun, J Pfleger, D Tilley, E Gao, WJ Koch The FASEB Journal 36, 2022 | 1 | 2022 |
Abstract MP247: Mitochondrial Complex V Is Regulated By GRK2 In The Heart K Ferrero, JM Pfleger, K Chuprun, E Barr, E Gao, WJ Koch Circulation Research 129 (Suppl_1), AMP247-AMP247, 2021 | 1 | 2021 |
Basic cardiovascular sciences scientific sessions 2019: integrative approaches to complex cardiovascular diseases RJ Vagnozzi, J Pfleger, S Sadayappan Circulation research 125 (10), 924-931, 2019 | 1 | 2019 |
G Protein-coupled receptor kinase 2 impairs fatty acid metabolism in the failing heart through novel mechanisms JM Pfleger, P Gross, J Johnson, E Gao, SR Houser, WJ Koch Circulation Research 123 (Suppl_1), A109-A109, 2018 | 1 | 2018 |
GRK2 is a Novel Regulator of Cardiac Mitochondrial Bioenergetics K Ferrero, JM Pfleger, K Chuprun, E Gao, WJ Koch Circulation 144 (Suppl_1), A12594-A12594, 2021 | | 2021 |