A holistic approach to targeting disease with polymeric nanoparticles CJ Cheng, GT Tietjen, JK Saucier-Sawyer, WM Saltzman Nature reviews Drug discovery 14 (4), 239-247, 2015 | 477 | 2015 |
Nanoparticle targeting to the endothelium during normothermic machine perfusion of human kidneys GT Tietjen, SA Hosgood, J DiRito, J Cui, D Deep, E Song, JR Kraehling, ... Science translational medicine 9 (418), eaam6764, 2017 | 137 | 2017 |
Focus on fundamentals: achieving effective nanoparticle targeting GT Tietjen, LG Bracaglia, WM Saltzman, JS Pober Trends in molecular medicine 24 (7), 598-606, 2018 | 107 | 2018 |
Surface chemistry governs cellular tropism of nanoparticles in the brain E Song, A Gaudin, AR King, YE Seo, HW Suh, Y Deng, J Cui, GT Tietjen, ... Nature communications 8 (1), 15322, 2017 | 99 | 2017 |
Ex vivo pretreatment of human vessels with siRNA nanoparticles provides protein silencing in endothelial cells J Cui, L Qin, J Zhang, P Abrahimi, H Li, G Li, GT Tietjen, G Tellides, ... Nature Communications 8 (1), 191, 2017 | 93 | 2017 |
A Molecular Mechanism for Differential Recognition of Membrane Phosphatidylserine by the Immune Regulatory Receptor Tim4 GT Tietjen, Z Gong, CH Chen, E Vargas, JE Crooks, KD Cao, CTR Heffern, ... Biophysical Journal 106 (2), 17a, 2014 | 92 | 2014 |
Quantitating endosomal escape of a library of polymers for mRNA delivery Y Jiang, Q Lu, Y Wang, E Xu, A Ho, P Singh, Y Wang, Z Jiang, F Yang, ... Nano letters 20 (2), 1117-1123, 2020 | 83 | 2020 |
The future of marginal kidney repair in the context of normothermic machine perfusion JR DiRito, SA Hosgood, GT Tietjen, ML Nicholson American Journal of Transplantation 18 (10), 2400-2408, 2018 | 77 | 2018 |
Lysis of cold-storage-induced microvascular obstructions for ex vivo revitalization of marginal human kidneys JR DiRito, SA Hosgood, M Reschke, C Albert, LG Bracaglia, ... American Journal of Transplantation 21 (1), 161-173, 2021 | 59 | 2021 |
A “top-down” approach to actuate poly (amine-co-ester) terpolymers for potent and safe mRNA delivery Y Jiang, A Gaudin, J Zhang, T Agarwal, E Song, AC Kauffman, GT Tietjen, ... Biomaterials 176, 122-130, 2018 | 57 | 2018 |
Cellular recovery after prolonged warm ischaemia of the whole body D Andrijevic, Z Vrselja, T Lysyy, S Zhang, M Skarica, A Spajic, D Dellal, ... Nature 608 (7922), 405-412, 2022 | 51 | 2022 |
Differential functional roles of fibroblasts and pericytes in the formation of tissue-engineered microvascular networks in vitro N Kosyakova, DD Kao, M Figetakis, F López-Giráldez, S Spindler, ... NPJ Regenerative medicine 5 (1), 1, 2020 | 51 | 2020 |
Nanomedicine gets personal GT Tietjen, WM Saltzman Science translational medicine 7 (314), 314fs47-314fs47, 2015 | 37 | 2015 |
ZFYVE21 is a complement-induced Rab5 effector that activates non-canonical NF-κB via phosphoinosotide remodeling of endosomes C Fang, TD Manes, L Liu, K Liu, L Qin, G Li, Z Tobiasova, ... Nature communications 10 (1), 2247, 2019 | 33 | 2019 |
Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression J Merola, M Reschke, RW Pierce, L Qin, S Spindler, T Baltazar, TD Manes, ... JCI insight 4 (20), 2019 | 30 | 2019 |
Poly (amine-co-ester) nanoparticles for effective Nogo-B knockdown in the liver J Cui, AS Piotrowski-Daspit, J Zhang, M Shao, LG Bracaglia, T Utsumi, ... Journal of Controlled Release 304, 259-267, 2019 | 28 | 2019 |
Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2, 3-dioxygenase 1 R Liu, J Merola, TD Manes, L Qin, GT Tietjen, F López-Giráldez, ... JCI insight 3 (5), 2018 | 19 | 2018 |
Coupling X-ray reflectivity and in silico binding to yield dynamics of membrane recognition by Tim1 GT Tietjen, JL Baylon, D Kerr, Z Gong, JM Henderson, CTR Heffern, ... Biophysical journal 113 (7), 1505-1519, 2017 | 18 | 2017 |
Sensitivity of peripheral membrane proteins to the membrane context: A case study of phosphatidylserine and the TIM proteins D Kerr, GT Tietjen, Z Gong, E Tajkhorshid, EJ Adams, KYC Lee Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (10), 2126-2133, 2018 | 16 | 2018 |
Enhancing potency of siRNA targeting fusion genes by optimization outside of target sequence K Gavrilov, YE Seo, GT Tietjen, J Cui, CJ Cheng, WM Saltzman Proceedings of the National Academy of Sciences 112 (48), E6597-E6605, 2015 | 16 | 2015 |