The somatic genomic landscape of glioblastoma CW Brennan, RGW Verhaak, A McKenna, B Campos, H Noushmehr, ... cell 155 (2), 462-477, 2013 | 5045 | 2013 |
The immune landscape of cancer V Thorsson, DL Gibbs, SD Brown, D Wolf, DS Bortone, THO Yang, ... Immunity 48 (4), 812-830. e14, 2018 | 4627 | 2018 |
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma R Galli, E Binda, U Orfanelli, B Cipelletti, A Gritti, S De Vitis, R Fiocco, ... Cancer research 64 (19), 7011-7021, 2004 | 3203 | 2004 |
Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas Cancer Genome Atlas Research Network New England Journal of Medicine 372 (26), 2481-2498, 2015 | 2961 | 2015 |
An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics J Liu, T Lichtenberg, KA Hoadley, LM Poisson, AJ Lazar, AD Cherniack, ... Cell 173 (2), 400-416. e11, 2018 | 2757 | 2018 |
Oncogenic signaling pathways in the cancer genome atlas F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ... Cell 173 (2), 321-337. e10, 2018 | 2581 | 2018 |
Comprehensive characterization of cancer driver genes and mutations MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ... Cell 173 (2), 371-385. e18, 2018 | 2247 | 2018 |
Effect of tumor-treating fields plus maintenance temozolomide vs maintenance temozolomide alone on survival in patients with glioblastoma: a randomized clinical trial R Stupp, S Taillibert, A Kanner, W Read, DM Steinberg, B Lhermitte, ... Jama 318 (23), 2306-2316, 2017 | 2208 | 2017 |
Cell-of-origin patterns dominate the molecular classification of 10,000 tumors from 33 types of cancer KA Hoadley, C Yau, T Hinoue, DM Wolf, AJ Lazar, E Drill, R Shen, ... Cell 173 (2), 291-304. e6, 2018 | 2104 | 2018 |
Machine learning identifies stemness features associated with oncogenic dedifferentiation TM Malta, A Sokolov, AJ Gentles, T Burzykowski, L Poisson, JN Weinstein, ... Cell 173 (2), 338-354. e15, 2018 | 1671 | 2018 |
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells SGM Piccirillo, BA Reynolds, N Zanetti, G Lamorte, E Binda, G Broggi, ... Nature 444 (7120), 761-765, 2006 | 1464 | 2006 |
Genomic and molecular landscape of DNA damage repair deficiency across the cancer genome atlas TA Knijnenburg, L Wang, MT Zimmermann, N Chambwe, GF Gao, ... Cell reports 23 (1), 239-254. e6, 2018 | 942 | 2018 |
Genomic and functional approaches to understanding cancer aneuploidy AM Taylor, J Shih, G Ha, GF Gao, X Zhang, AC Berger, SE Schumacher, ... Cancer cell 33 (4), 676-689. e3, 2018 | 913 | 2018 |
Spatial organization and molecular correlation of tumor-infiltrating lymphocytes using deep learning on pathology images J Saltz, R Gupta, L Hou, T Kurc, P Singh, V Nguyen, D Samaras, ... Cell reports 23 (1), 181-193. e7, 2018 | 877 | 2018 |
The cancer genome atlas comprehensive molecular characterization of renal cell carcinoma CJ Ricketts, AA De Cubas, H Fan, CC Smith, M Lang, E Reznik, R Bowlby, ... Cell reports 23 (1), 313-326. e5, 2018 | 858 | 2018 |
NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts X Fan, L Khaki, TS Zhu, ME Soules, CE Talsma, N Gul, C Koh, J Zhang, ... Stem cells 28 (1), 5-16, 2010 | 788 | 2010 |
Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma EE Bar, A Chaudhry, A Lin, X Fan, K Schreck, W Matsui, S Piccirillo, ... Stem cells 25 (10), 2524-2533, 2007 | 771 | 2007 |
Comprehensive analysis of alternative splicing across tumors from 8,705 patients A Kahles, KV Lehmann, NC Toussaint, M Hüser, SG Stark, ... Cancer cell 34 (2), 211-224. e6, 2018 | 743 | 2018 |
Pathogenic germline variants in 10,389 adult cancers K Huang, RJ Mashl, Y Wu, DI Ritter, J Wang, C Oh, M Paczkowska, ... Cell 173 (2), 355-370. e14, 2018 | 737 | 2018 |
Scalable open science approach for mutation calling of tumor exomes using multiple genomic pipelines K Ellrott, MH Bailey, G Saksena, KR Covington, C Kandoth, C Stewart, ... Cell systems 6 (3), 271-281. e7, 2018 | 656 | 2018 |