| Rho-kinase/myosin light chain kinase pathway plays a key role in the impairment of bile canaliculi dynamics induced by cholestatic drugs A Sharanek, A Burban, M Burbank, R Le Guevel, R Li, A Guillouzo, ... Scientific reports 6 (1), 24709, 2016 | 83 | 2016 |
| Comparative localization and functional activity of the main hepatobiliary transporters in HepaRG cells and primary human hepatocytes P Bachour-El Azzi, A Sharanek, A Burban, R Li, RL Guével, ... Toxicological Sciences 145 (1), 157-168, 2015 | 81 | 2015 |
| Different dose-dependent mechanisms are involved in early cyclosporine a-induced cholestatic effects in hepaRG cells A Sharanek, PBE Azzi, H Al-Attrache, CC Savary, L Humbert, D Rainteau, ... Toxicological Sciences 141 (1), 244-253, 2014 | 69 | 2014 |
| OSMR controls glioma stem cell respiration and confers resistance of glioblastoma to ionizing radiation A Sharanek, A Burban, M Laaper, E Heckel, JS Joyal, VD Soleimani, ... Nature communications 11 (1), 4116, 2020 | 59 | 2020 |
| Myf6/MRF4 is a myogenic niche regulator required for the maintenance of the muscle stem cell pool F Lazure, DM Blackburn, AH Corchado, K Sahinyan, N Karam, ... EMBO reports 21 (12), e49499, 2020 | 57 | 2020 |
| Cellular accumulation and toxic effects of bile acids in cyclosporine A-treated HepaRG hepatocytes A Sharanek, A Burban, L Humbert, P Bachour-El Azzi, N Felix-Gomes, ... Toxicological Sciences 147 (2), 573-587, 2015 | 57 | 2015 |
| Early alterations of bile canaliculi dynamics and the rho kinase/myosin light chain kinase pathway are characteristics of drug-induced intrahepatic cholestasis MG Burbank, A Burban, A Sharanek, RJ Weaver, C Guguen-Guillouzo, ... Drug Metabolism and Disposition 44 (11), 1780-1793, 2016 | 54 | 2016 |
| Endoplasmic reticulum stress precedes oxidative stress in antibiotic-induced cholestasis and cytotoxicity in human hepatocytes A Burban, A Sharanek, C Guguen-Guillouzo, A Guillouzo Free Radical Biology and Medicine 115, 166-178, 2018 | 49 | 2018 |
| Impact of inflammation on chlorpromazine-induced cytotoxicity and cholestatic features in HepaRG cells P Bachour-El Azzi, A Sharanek, Z Abdel-Razzak, S Antherieu, ... Drug Metabolism and Disposition 42 (9), 1556-1566, 2014 | 43 | 2014 |
| Penicillinase-resistant antibiotics induce non-immune-mediated cholestasis through HSP27 activation associated with PKC/P38 and PI3K/AKT signaling pathways A Burban, A Sharanek, R Hüe, M Gay, S Routier, A Guillouzo, ... Scientific reports 7 (1), 1815, 2017 | 32 | 2017 |
| Differential sensitivity of metabolically competent and non-competent HepaRG cells to apoptosis induced by diclofenac combined or not with TNF-α H Al-Attrache, A Sharanek, A Burban, M Burbank, T Gicquel, ... Toxicology Letters 258, 71-86, 2016 | 31 | 2016 |
| Impact of isomalathion on malathion cytotoxicity and genotoxicity in human HepaRG cells R Josse, A Sharanek, CC Savary, A Guillouzo Chemico-Biological Interactions 209, 68-76, 2014 | 31 | 2014 |
| Progressive and preferential cellular accumulation of hydrophobic bile acids induced by cholestatic drugs is associated with inhibition of their amidation and sulfation A Sharanek, A Burban, L Humbert, C Guguen-Guillouzo, D Rainteau, ... Drug Metabolism and Disposition 45 (12), 1292-1303, 2017 | 27 | 2017 |
| Transcriptional control of brain tumor stem cells by a carbohydrate binding protein A Sharanek, A Burban, A Hernandez-Corchado, A Madrigal, ... Cell reports 36 (9), 2021 | 22 | 2021 |
| From the cover: mechanisticInsights in cytotoxic and cholestatic potential of the endothelial receptor antagonists using hepaRG cells MG Burbank, A Sharanek, A Burban, H Mialanne, H Aerts, ... Toxicological Sciences 157 (2), 451-464, 2017 | 17 | 2017 |
| Pro-inflammatory cytokines enhance dilatation of bile canaliculi caused by cholestatic antibiotics A Sharanek, A Burban, N Ciriaci, A Guillouzo Toxicology in Vitro 58, 51-59, 2019 | 12 | 2019 |
| Predictive value of cellular accumulation of hydrophobic bile acids as a marker of cholestatic drug potential A Burban, A Sharanek, L Humbert, T Eguether, C Guguen-Guillouzo, ... Toxicological Sciences 168 (2), 474-485, 2019 | 8 | 2019 |
| Endotoxin regulates matrix genes increasing reactive oxygen species generation by intercellular communication between palmitate‐treated hepatocyte and stellate cell W Dornas, D Glaise, A Bodin, A Sharanek, A Burban, D Le Guillou, ... Journal of cellular physiology 234 (1), 122-133, 2019 | 6 | 2019 |
| A dynamic mathematical model of bile acid clearance in HepaRG cells D Kaschek, A Sharanek, A Guillouzo, J Timmer, RJ Weaver Toxicological Sciences 161 (1), 48-57, 2018 | 6 | 2018 |
| Hepatic 3D spheroid models for the detection and study of compounds with cholestatic liability. Sci. Rep. 6, 35434 DFG Hendriks, L Fredriksson Puigvert, S Messner, W Mortiz, ... | 6 | 2016 |
