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Simon Ng
Simon Ng
Covant Therapeutics
在 covanttx.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Diversity of phage-displayed libraries of peptides during panning and amplification
R Derda, SKY Tang, SC Li, S Ng, W Matochko, MR Jafari
Molecules 16 (2), 1776-1803, 2011
2622011
Interfacing glycosylated carbon‐nanotube‐network devices with living cells to detect dynamic secretion of biomolecules
HG Sudibya, J Ma, X Dong, S Ng, LJ Li, XW Liu, P Chen
Angewandte Chemie International Edition 48 (15), 2723-2726, 2009
2022009
bioPROTACs as versatile modulators of intracellular therapeutic targets including proliferating cell nuclear antigen (PCNA)
S Lim, R Khoo, KM Peh, J Teo, SC Chang, S Ng, GL Beilhartz, RA Melnyk, ...
Proceedings of the National Academy of Sciences 117 (11), 5791-5800, 2020
1062020
Quantitative synthesis of genetically encoded glycopeptide libraries displayed on M13 phage
S Ng, MR Jafari, WL Matochko, R Derda
ACS chemical biology 7 (9), 1482-1487, 2012
992012
Discovery of light-responsive ligands through screening of a light-responsive genetically encoded library
MR Jafari, L Deng, PI Kitov, S Ng, WL Matochko, KF Tjhung, A Zeberoff, ...
ACS chemical biology 9 (2), 443-450, 2014
942014
Rapid, hydrolytically stable modification of aldehyde-terminated proteins and phage libraries
PI Kitov, DF Vinals, S Ng, KF Tjhung, R Derda
Journal of the American Chemical Society 136 (23), 8149-8152, 2014
842014
Genetically encoded fragment-based discovery of glycopeptide ligands for carbohydrate-binding proteins
S Ng, E Lin, PI Kitov, KF Tjhung, OO Gerlits, L Deng, B Kasper, A Sood, ...
Journal of the American Chemical Society 137 (16), 5248-5251, 2015
822015
Bacteriophages and viruses as a support for organic synthesis and combinatorial chemistry
S Ng, MR Jafari, R Derda
ACS chemical biology 7 (1), 123-138, 2012
792012
Silent encoding of chemical post-translational modifications in phage-displayed libraries
KF Tjhung, PI Kitov, S Ng, EN Kitova, L Deng, JS Klassen, R Derda
Journal of the American Chemical Society 138 (1), 32-35, 2016
642016
Phage-displayed macrocyclic glycopeptide libraries
S Ng, R Derda
Organic & Biomolecular Chemistry 14 (24), 5539-5545, 2016
632016
Macrocyclic α helical peptide therapeutic modality: A perspective of learnings and challenges
TK Sawyer, AW Partridge, HYK Kaan, YC Juang, S Lim, C Johannes, ...
Bioorganic & Medicinal Chemistry 26 (10), 2807-2815, 2018
622018
Exquisitely specific anti-KRAS biodegraders inform on the cellular prevalence of nucleotide-loaded states
S Lim, R Khoo, YC Juang, P Gopal, H Zhang, C Yeo, KM Peh, J Teo, S Ng, ...
ACS central science 7 (2), 274-291, 2020
612020
Uniform amplification of phage display libraries in monodisperse emulsions
WL Matochko, S Ng, MR Jafari, J Romaniuk, SKY Tang, R Derda
Methods 58 (1), 18-27, 2012
612012
Sugar‐based synthesis of Tamiflu and its inhibitory effects on cell secretion
J Ma, Y Zhao, S Ng, J Zhang, J Zeng, A Than, P Chen, XW Liu
Chemistry–A European Journal 16 (15), 4533-4540, 2010
582010
Incorporation of putative helix-breaking amino acids in the design of novel stapled peptides: Exploring biophysical and cellular permeability properties
AW Partridge, HYK Kaan, YC Juang, A Sadruddin, S Lim, CJ Brown, S Ng, ...
Molecules 24 (12), 2292, 2019
552019
Macrocyclization of an all-d linear α-helical peptide imparts cellular permeability
S Kannan, PGA Aronica, S Ng, DTG Lian, Y Frosi, S Chee, J Shimin, ...
Chemical Science 11 (21), 5577-5591, 2020
412020
De-risking drug discovery of intracellular targeting peptides: screening strategies to eliminate false-positive hits
S Ng, YC Juang, A Chandramohan, HYK Kaan, A Sadruddin, TY Yuen, ...
ACS Medicinal Chemistry Letters 11 (10), 1993-2001, 2020
292020
Genetically encoded fragment-based discovery
R Derda, S Ng
Current Opinion in Chemical Biology 50, 128-137, 2019
252019
Genetically-encoded fragment-based discovery of glycopeptide ligands for DC-SIGN
S Ng, NJ Bennett, J Schulze, N Gao, C Rademacher, R Derda
Bioorganic & Medicinal Chemistry 26 (19), 5368-5377, 2018
252018
Chemical posttranslational modification of phage-displayed peptides
S Ng, KF Tjhung, BM Paschal, CJ Noren, R Derda
Peptide Libraries: Methods and Protocols, 155-172, 2015
242015
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