Advanced applications of RNA sequencing and challenges Y Han, S Gao, K Muegge, W Zhang, B Zhou Bioinformatics and biology insights 9, BBI. S28991, 2015 | 361 | 2015 |
Suboptimization of developmental enhancers EK Farley, KM Olson, W Zhang, AJ Brandt, DS Rokhsar, MS Levine Science 350 (6258), 325-328, 2015 | 324 | 2015 |
Systematic evaluation of molecular networks for discovery of disease genes JK Huang, DE Carlin, MK Yu, W Zhang, JF Kreisberg, P Tamayo, T Ideker Cell systems 6 (4), 484-495. e5, 2018 | 239 | 2018 |
mTORC2 regulates amino acid metabolism in cancer by phosphorylation of the cystine-glutamate antiporter xCT Y Gu, CP Albuquerque, D Braas, W Zhang, GR Villa, J Bi, S Ikegami, ... Molecular cell 67 (1), 128-138. e7, 2017 | 174 | 2017 |
Syntax compensates for poor binding sites to encode tissue specificity of developmental enhancers EK Farley, KM Olson, W Zhang, DS Rokhsar, MS Levine Proceedings of the National Academy of Sciences 113 (23), 6508-6513, 2016 | 167 | 2016 |
Oncogene amplification in growth factor signaling pathways renders cancers dependent on membrane lipid remodeling J Bi, TA Ichu, C Zanca, H Yang, W Zhang, Y Gu, S Chowdhry, A Reed, ... Cell metabolism 30 (3), 525-538. e8, 2019 | 160 | 2019 |
A global transcriptional network connecting noncoding mutations to changes in tumor gene expression W Zhang, A Bojorquez-Gomez, DO Velez, G Xu, KS Sanchez, JP Shen, ... Nature genetics 50 (4), 613-620, 2018 | 148 | 2018 |
Loss-of-function mutations in co-chaperone BAG3 destabilize small HSPs and cause cardiomyopathy X Fang, J Bogomolovas, T Wu, W Zhang, C Liu, J Veevers, MJ Stroud, ... The Journal of clinical investigation 127 (8), 3189-3200, 2017 | 146 | 2017 |
ELAV links paused Pol II to alternative polyadenylation in the Drosophila nervous system K Oktaba, W Zhang, TS Lotz, DJ Jun, SB Lemke, SP Ng, E Esposito, ... Molecular cell 57 (2), 341-348, 2015 | 107 | 2015 |
Dynamic interactions between Bombyx mori nucleopolyhedrovirus and its host cells revealed by transcriptome analysis J Xue, N Qiao, W Zhang, RL Cheng, XQ Zhang, YY Bao, YP Xu, LZ Gu, ... Journal of virology 86 (13), 7345-7359, 2012 | 106 | 2012 |
Integrating genomic, epigenomic, and transcriptomic features reveals modular signatures underlying poor prognosis in ovarian cancer W Zhang, Y Liu, N Sun, D Wang, J Boyd-Kirkup, X Dou, JDJ Han Cell reports 4 (3), 542-553, 2013 | 99 | 2013 |
Multiple routes to oncogenesis are promoted by the human papillomavirus–host protein network M Eckhardt, W Zhang, AM Gross, J Von Dollen, JR Johnson, ... Cancer discovery 8 (11), 1474-1489, 2018 | 80 | 2018 |
Correlation of SRSF1 and PRMT1 expression with clinical status of pediatric acute lymphoblastic leukemia L Zou, H Zhang, C Du, X Liu, S Zhu, W Zhang, Z Li, C Gao, X Zhao, M Mei, ... Journal of hematology & oncology 5 (1), 1-11, 2012 | 72 | 2012 |
eIF5A-PEAK1 signaling regulates YAP1/TAZ protein expression and pancreatic cancer cell growth J Strnadel, S Choi, K Fujimura, H Wang, W Zhang, M Wyse, T Wright, ... Cancer research 77 (8), 1997-2007, 2017 | 68 | 2017 |
Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug J Bi, A Khan, J Tang, AM Armando, S Wu, W Zhang, RC Gimple, A Reed, ... Cell reports 37 (5), 109957, 2021 | 55 | 2021 |
Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription H Lu, Z Li, W Zhang, U Schulze-Gahmen, Y Xue, Q Zhou Nucleic acids research 43 (12), 5868-5879, 2015 | 55 | 2015 |
Disruption of NSD1 in head and neck cancer promotes favorable chemotherapeutic responses linked to hypomethylation N Bui, JK Huang, A Bojorquez-Gomez, K Licon, KS Sanchez, SN Tang, ... Molecular cancer therapeutics 17 (7), 1585-1594, 2018 | 54 | 2018 |
Gene expression–based classification and regulatory networks of pediatric acute lymphoblastic leukemia Z Li, W Zhang, M Wu, S Zhu, C Gao, L Sun, R Zhang, N Qiao, H Xue, Y Hu, ... Blood, The Journal of the American Society of Hematology 114 (20), 4486-4493, 2009 | 53 | 2009 |
Classifying tumors by supervised network propagation W Zhang, J Ma, T Ideker Bioinformatics 34 (13), i484-i493, 2018 | 45 | 2018 |
Systems biology in aging: linking the old and the young L Hou, J Huang, C D Green, J Boyd-Kirkup, W Zhang, X Yu, W Gong, ... Current genomics 13 (7), 558-565, 2012 | 30 | 2012 |