Synthesis of Helix 69 of Escherichia coli 23S rRNA Containing Its Natural Modified Nucleosides, m3Ψ and Ψ HMP Chui, JP Desaulniers, SA Scaringe, CS Chow The Journal of organic chemistry 67 (25), 8847-8854, 2002 | 95 | 2002 |
Effects of nucleotide substitution and modification on the stability and structure of helix 69 from 28S rRNA M Sumita, JP Desaulniers, YC Chang, HMP Chui, L CLOS, CS Chow Rna 11 (9), 1420-1429, 2005 | 74 | 2005 |
Synthesis of 15N-Enriched Pseudouridine Derivatives JP Desaulniers, B Ksebati, CS Chow Organic Letters 5 (22), 4093-4096, 2003 | 60 | 2003 |
Chemical architecture and applications of nucleic acid derivatives containing 1, 2, 3-triazole functionalities synthesized via click chemistry T Efthymiou, W Gong, JP Desaulniers Molecules 17 (11), 12665-12703, 2012 | 59 | 2012 |
Pseudouridines in rRNA helix 69 play a role in loop stacking interactions JP Desaulniers, YC Chang, R Aduri, SC Abeysirigunawardena, ... Organic & biomolecular chemistry 6 (21), 3892-3895, 2008 | 50 | 2008 |
Inter-year repeatability study of volatile organic compounds from surface decomposition of human analogues S Stadler, JP Desaulniers, SL Forbes International journal of legal medicine 129, 641-650, 2015 | 44 | 2015 |
Targeted delivery and enhanced gene-silencing activity of centrally modified folic acid–siRNA conjugates L Salim, G Islam, JP Desaulniers Nucleic acids research 48 (1), 75-85, 2020 | 41 | 2020 |
Efficient synthesis and cell-based silencing activity of siRNAS that contain triazole backbone linkages TC Efthymiou, V Huynh, J Oentoro, B Peel, JP Desaulniers Bioorganic & medicinal chemistry letters 22 (4), 1722-1726, 2012 | 41 | 2012 |
Gene-silencing properties of siRNAs that contain internal amide-bond linkages W Gong, JP Desaulniers Bioorganic & medicinal chemistry letters 22 (22), 6934-6937, 2012 | 30 | 2012 |
Synthesis, Derivatization and Photochemical Control of ortho‐Functionalized Tetrachlorinated Azobenzene‐Modified siRNAs ML Hammill, G Islam, JP Desaulniers ChemBioChem 21 (16), 2367-2372, 2020 | 29 | 2020 |
siRNAzos: A new class of azobenzene‐containing siRNAs that can photochemically regulate gene expression ML Hammill, C Isaacs‐Trépanier, JP Desaulniers ChemistrySelect 2 (30), 9810-9814, 2017 | 29 | 2017 |
Evaluation of siRNAs that contain internal variable-length spacer linkages TC Efthymiou, B Peel, V Huynh, JP Desaulniers Bioorganic & medicinal chemistry letters 22 (17), 5590-5594, 2012 | 29 | 2012 |
Pasteurization, storage conditions and viral concentration methods influence RT-qPCR detection of SARS-CoV-2 RNA in wastewater G Islam, A Gedge, L Lara-Jacobo, A Kirkwood, D Simmons, ... Science of the Total Environment 821, 153228, 2022 | 26 | 2022 |
New decomposition stages to describe scenarios involving the partial and complete exclusion of insects JL Comstock, JP Desaulniers, HN LeBlanc, SL Forbes Canadian Society of Forensic Science Journal 48 (1), 1-19, 2015 | 26 | 2015 |
Sheep red blood cells armed with anti-CD20 single-chain variable fragments (scFvs) fused to a glycosylphosphatidylinositol (GPI) anchor: a strategy to target CD20-positive … N Hamdy, AS Goustin, JP Desaulniers, M Li, CS Chow, A Al-Katib Journal of immunological methods 297 (1-2), 109-124, 2005 | 24 | 2005 |
Reversible control of RNA interference by siRNAzos ML Hammill, G Islam, JP Desaulniers Organic & Biomolecular Chemistry 18 (1), 41-46, 2020 | 22 | 2020 |
Inhibition of ErbB2 (Her2) expression with small molecule transcription factor mimics LW Lee, CEC Taylor, JP Desaulniers, M Zhang, JW Højfeldt, Q Pan, ... Bioorganic & medicinal chemistry letters 19 (21), 6233-6236, 2009 | 22 | 2009 |
Solution conformations of two naturally occurring RNA nucleosides: 3-Methyluridine and 3-methylpseudouridine JP Desaulniers, HMP Chui, CS Chow Bioorganic & medicinal chemistry 13 (24), 6777-6781, 2005 | 17 | 2005 |
Detection of SARS-CoV-2 proteins in wastewater samples by mass spectrometry LR Lara-Jacobo, G Islam, JP Desaulniers, AE Kirkwood, DBD Simmons Environmental science & technology 56 (8), 5062-5070, 2022 | 16 | 2022 |
Expanding the repertoire of small molecule transcriptional activation domains RJ Casey, JP Desaulniers, JW Hojfeldt, AK Mapp Bioorganic & medicinal chemistry 17 (3), 1034-1043, 2009 | 16 | 2009 |