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Jeremy M. Simon
Jeremy M. Simon
Dana-Farber Cancer Institute, Harvard T.H. Chan School of Public Health
在 ds.dfci.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
An integrated encyclopedia of DNA elements in the human genome
ENCODE Project Consortium
Nature 489 (7414), 57-74, 2012
168202012
The accessible chromatin landscape of the human genome
RE Thurman, E Rynes, R Humbert, J Vierstra, MT Maurano, E Haugen, ...
Nature 489 (7414), 75-82, 2012
30932012
A map of open chromatin in human pancreatic islets
KJ Gaulton, T Nammo, L Pasquali, JM Simon, PG Giresi, MP Fogarty, ...
Nature genetics 42 (3), 255-259, 2010
6482010
Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity
L Song, Z Zhang, LL Grasfeder, AP Boyle, PG Giresi, BK Lee, ...
Genome research 21 (10), 1757-1767, 2011
6282011
Using formaldehyde-assisted isolation of regulatory elements (FAIRE) to isolate active regulatory DNA
JM Simon, PG Giresi, IJ Davis, JD Lieb
Nature protocols 7 (2), 256-267, 2012
4142012
Single-cell transcriptomic analysis of mouse neocortical development
L Loo, JM Simon, L Xing, ES McCoy, JK Niehaus, J Guo, ES Anton, ...
Nature communications 10 (1), 134, 2019
2612019
An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation
GP Souroullas, WR Jeck, JS Parker, JM Simon, JY Liu, J Paulk, J Xiong, ...
Nature medicine 22 (6), 632-640, 2016
2152016
Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects
JM Simon, KE Hacker, D Singh, AR Brannon, JS Parker, M Weiser, TH Ho, ...
Genome research 24 (2), 241-250, 2014
2062014
VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma
J Zhang, T Wu, J Simon, M Takada, R Saito, C Fan, XD Liu, E Jonasch, ...
Science 361 (6399), 290-295, 2018
1452018
BRG1/SMARCA4 inactivation promotes non–small cell lung cancer aggressiveness by altering chromatin organization
T Orvis, A Hepperla, V Walter, S Song, J Simon, J Parker, MD Wilkerson, ...
Cancer research 74 (22), 6486-6498, 2014
1392014
Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration
BL Pearson, JM Simon, ES McCoy, G Salazar, G Fragola, MJ Zylka
Nature communications 7 (1), 11173, 2016
1292016
Tumor-specific retargeting of an oncogenic transcription factor chimera results in dysregulation of chromatin and transcription
M Patel, JM Simon, MD Iglesia, SB Wu, AW McFadden, JD Lieb, IJ Davis
Genome research 22 (2), 259-270, 2012
1282012
Gene length matters in neurons
MJ Zylka, JM Simon, BD Philpot
Neuron 86 (2), 353-355, 2015
1242015
Cas9 gene therapy for Angelman syndrome traps Ube3a-ATS long non-coding RNA
JM Wolter, H Mao, G Fragola, JM Simon, JL Krantz, HO Bazick, B Oztemiz, ...
Nature 587 (7833), 281-284, 2020
1192020
Molecular classification of Crohn's disease reveals two clinically relevant subtypes
M Weiser, JM Simon, B Kochar, A Tovar, JW Israel, A Robinson, ...
Gut, gutjnl-2016-312518, 2016
1192016
scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy
JK Ocasio, B Babcock, D Malawsky, SJ Weir, L Loo, JM Simon, MJ Zylka, ...
Nature communications 10 (1), 5829, 2019
962019
A myelin-related transcriptomic profile is shared by Pitt–Hopkins syndrome models and human autism spectrum disorder
BDN Phan, JF Bohlen, BA Davis, Z Ye, HY Chen, B Mayfield, SR Sripathy, ...
Nature neuroscience 23 (3), 375-385, 2020
952020
Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models
J Guo, JM Otis, SK Suciu, C Catalano, L Xing, S Constable, D Wachten, ...
Developmental Cell 51 (6), 759-774. e5, 2019
872019
Spinal macrophages resolve nociceptive hypersensitivity after peripheral injury
JK Niehaus, B Taylor-Blake, L Loo, JM Simon, MJ Zylka
Neuron 109 (8), 1274-1282. e6, 2021
822021
Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma
RS McNeill, DA Canoutas, TJ Stuhlmiller, HD Dhruv, DM Irvin, RE Bash, ...
Neuro-oncology 19 (11), 1469-1480, 2017
582017
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