Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice H Zaher, JTM Buters, JM Ward, MK Bruno, AM Lucas, ST Stern, ... Toxicology and applied pharmacology 152 (1), 193-199, 1998 | 385 | 1998 |
Oxidative and electrophilic stress induces multidrug resistance–associated protein transporters via the nuclear factor‐E2–related factor‐2 transcriptional pathway JM Maher, MZ Dieter, LM Aleksunes, AL Slitt, G Guo, Y Tanaka, ... Hepatology 46 (5), 1597-1610, 2007 | 374 | 2007 |
Induction of the multidrug resistance-associated protein family of transporters by chemical activators of receptor-mediated pathways in mouse liver JM Maher, X Cheng, AL Slitt, MZ Dieter, CD Klaassen Drug metabolism and disposition 33 (7), 956-962, 2005 | 322 | 2005 |
Tissue distribution and hormonal regulation of the breast cancer resistance protein (Bcrp/Abcg2) in rats and mice Y Tanaka, AL Slitt, TM Leazer, JM Maher, CD Klaassen Biochemical and biophysical research communications 326 (1), 181-187, 2004 | 252 | 2004 |
Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice JM Maher, AL Slitt, NJ Cherrington, X Cheng, CD Klaassen Drug Metabolism and Disposition 33 (7), 947-955, 2005 | 249 | 2005 |
Tissue distribution and renal developmental changes in rat organic cation transporter mRNA levels AL Slitt, NJ Cherrington, DP Hartley, TM Leazer, CD Klaassen Drug Metabolism and Disposition 30 (2), 212-219, 2002 | 225 | 2002 |
Regulation of hepatic transporters by xenobiotic receptors CD Klaassen, AL Slitt Current drug metabolism 6 (4), 309-328, 2005 | 210 | 2005 |
Lipopolysaccharide-mediated regulation of hepatic transporter mRNA levels in rats NJ Cherrington, AL Slitt, N Li, CD Klaassen Drug Metabolism and Disposition 32 (7), 734-741, 2004 | 207 | 2004 |
Enhanced Nrf2 activity worsens insulin resistance, impairs lipid accumulation in adipose tissue, and increases hepatic steatosis in leptin-deficient mice J Xu, SR Kulkarni, AC Donepudi, VR More, AL Slitt Diabetes 61 (12), 3208-3218, 2012 | 192 | 2012 |
Induction of Mrp3 and Mrp4 transporters during acetaminophen hepatotoxicity is dependent on Nrf2 LM Aleksunes, AL Slitt, JM Maher, LM Augustine, MJ Goedken, JY Chan, ... Toxicology and applied pharmacology 226 (1), 74-83, 2008 | 182 | 2008 |
Differential expression of mouse hepatic transporter genes in response to acetaminophen and carbon tetrachloride LM Aleksunes, AM Slitt, NJ Cherrington, MS Thibodeau, CD Klaassen, ... Toxicological Sciences 83 (1), 44-52, 2005 | 152 | 2005 |
Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2 CD Fisher, LM Augustine, JM Maher, DM Nelson, AL Slitt, CD Klaassen, ... Drug Metabolism and Disposition 35 (6), 995-1000, 2007 | 148 | 2007 |
Drug-metabolizing enzyme and transporter expression in a mouse model of diabetes and obesity Q Cheng, LM Aleksunes, JE Manautou, NJ Cherrington, GL Scheffer, ... Molecular pharmaceutics 5 (1), 77-91, 2008 | 142 | 2008 |
Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease RN Hardwick, DW Ferreira, VR More, AD Lake, Z Lu, JE Manautou, ... Drug metabolism and disposition 41 (3), 554-561, 2013 | 135 | 2013 |
Enhanced acetaminophen toxicity by activation of the pregnane X receptor GL Guo, JS Moffit, CJ Nicol, JM Ward, LA Aleksunes, AL Slitt, SA Kliewer, ... Toxicological sciences 82 (2), 374-380, 2004 | 130 | 2004 |
Early growth response factor-1 is critical for cholestatic liver injury ND Kim, JOK Moon, AL Slitt, BL Copple Toxicological sciences 90 (2), 586-595, 2006 | 127 | 2006 |
Metallothionein-I/II knockout mice are sensitive to acetaminophen-induced hepatotoxicity J Liu, Y Liu, D Hartley, CD Klaassen, SE Shehin-Johnson, A Lucas, ... Journal of Pharmacology and Experimental Therapeutics 289 (1), 580-586, 1999 | 118 | 1999 |
Bromobenzene-induced hepatotoxicity at the transcriptome level WHM Heijne, AL Slitt, PJ van Bladeren, JP Groten, CD Klaassen, ... Toxicological Sciences 79 (2), 411-422, 2004 | 117 | 2004 |
THIOACETAMIDE-INDUCED HEPATIC NECROSIS. II: PHARMACOKINETICS OF THIOACETAMIDE AND THIOACETAMIDE-S-OXIDE IN THE RAT WR Porter, P WR, G MJ, N RA | 117 | 1979 |
Alterations in transporter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1α JM Maher, AL Slitt, TN Callaghan, X Cheng, C Cheung, FJ Gonzalez, ... Biochemical pharmacology 72 (4), 512-522, 2006 | 113 | 2006 |