Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis R Romero, VI Sayin, SM Davidson, MR Bauer, SX Singh, SE LeBoeuf, ... Nature medicine 23 (11), 1362-1368, 2017 | 566 | 2017 |
Rapid modelling of cooperating genetic events in cancer through somatic genome editing FJ Sánchez-Rivera, T Papagiannakopoulos, R Romero, T Tammela, ... Nature 516 (7531), 428-431, 2014 | 436 | 2014 |
Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers GR Hoffman, R Rahal, F Buxton, K Xiang, G McAllister, E Frias, ... Proceedings of the National Academy of Sciences 111 (8), 3128-3133, 2014 | 424 | 2014 |
Pharmacological and genomic profiling identifies NF-κB–targeted treatment strategies for mantle cell lymphoma R Rahal, M Frick, R Romero, JM Korn, R Kridel, F Chun Chan, B Meissner, ... Nature medicine 20 (1), 87-92, 2014 | 404 | 2014 |
Identification of DHODH as a therapeutic target in small cell lung cancer L Li, SR Ng, CI Colón, BJ Drapkin, PP Hsu, Z Li, CS Nabel, CA Lewis, ... Science translational medicine 11 (517), eaaw7852, 2019 | 105 | 2019 |
Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1 R Romero, FJ Sánchez-Rivera, PMK Westcott, KL Mercer, A Bhutkar, ... Nature Cancer 1 (6), 589-602, 2020 | 47 | 2020 |
Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform S Naranjo, CM Cabana, LM LaFave, R Romero, SL Shanahan, A Bhutkar, ... Genes & Development 36 (15-16), 936-949, 2022 | 19 | 2022 |
Rapid interrogation of cancer cell of origin through CRISPR editing W Feng, Z Cao, PX Lim, H Zhao, H Luo, N Mao, YS Lee, AA Rivera, ... Proceedings of the National Academy of Sciences 118 (32), e2110344118, 2021 | 17 | 2021 |
A GATA4-regulated secretory program suppresses tumors through recruitment of cytotoxic CD8 T cells RS Patel, R Romero, EV Watson, AC Liang, M Burger, PMK Westcott, ... Nature communications 13 (1), 256, 2022 | 10 | 2022 |
Ramirez, J. PE Rodriguez, R Rodriguez, VMPLI De, VDA De Emergencia, ... | 3 | 2005 |
The neuroendocrine transition in prostate cancer is dynamic and dependent on ASCL1 R Romero, T Chu, TJ González-Robles, P Smith, Y Xie, H Kaur, S Yoder, ... bioRxiv, 2024 | 1 | 2024 |
Methods of treating cancers having a deregulated nrf2/keap1 pathway T Papagiannakopoulos, T Jacks, R Romero US Patent App. 18/530,612, 2024 | | 2024 |
Abstract IA17: The role of the senescence-associated secretory phenotype in cancer RS Patel, R Romero, AC Liang, EV Watson, M Burger, PMK Westcott, ... Cancer Immunology Research 9 (2_Supplement), IA17-IA17, 2021 | | 2021 |
Publisher Correction: Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1 R Romero, FJ Sánchez-Rivera, PMK Westcott, KL Mercer, A Bhutkar, ... Nature Cancer 1 (9), 935-935, 2020 | | 2020 |
Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1 (vol 1, pg 589, 2020) R Romero, FJ Sanchez-Rivera, PMK Westcott, KL Mercer, A Bhutkar, ... NATURE CANCER 1 (9), 935-935, 2020 | | 2020 |
Identification of genotype-specific dependencies in Keap1-deficient lung adenocarcinoma R Romero Massachusetts Institute of Technology, 2019 | | 2019 |
Methods of treating cancers having a deregulated nrf2/keap1 pathway T Papagiannakopoulos, T Jacks, R Romero | | 2018 |
Abstract A43: Loss of Keap1 promotes KRAS-driven lung cancer and results in genotype-specific vulnerabilities R Romero, VI Sayin, DM Shawn, M Bauer, SX Singh, S LeBoeuf, ... Cancer Research 78 (10_Supplement), A43-A43, 2018 | | 2018 |
Loss of Keap1 promotes KRAS-driven lung cancer and results in genotype-specific vulnerabilities. R Romero, VI Sayin, DM Shawn, M Bauer, SX Singh, S LeBoeuf, ... CANCER RESEARCH 78 (10), 50-50, 2018 | | 2018 |
Abstract PR06: A functional screen of the epigenome identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers. Z Jagani, G Hoffman, R Rahal, F Buxton, G McAllister, K Xiang, E Frias, ... Molecular Cancer Therapeutics 12 (11_Supplement), PR06-PR06, 2013 | | 2013 |